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Page 1
GIP receptor antagonism eliminates paradoxical growth hormone secretion in some patients with acromegaly.
Jensen MH, Gasbjerg LS, Skov-Jeppesen K, Jacobsen JCB, Poulsen SS, Zhou C, Jakubauskaite R, Poulsen FR, Bonde C, Albarazi M, Halle B, Christiansen CB, Sanni SJ, Byberg S, Hoe B, Holst JJ, Dela F, Rasmussen AK, Knop FK, Arlien-Søborg MC, Melmed S, Jørgensen JOL, Andersen MS, Hartmann B, Klose MC, Feldt-Rasmussen U, Sparre-Ulrich AH, Rosenkilde MM. Jensen MH, et al. Among authors: christiansen cb. J Clin Endocrinol Metab. 2024 Aug 22:dgae583. doi: 10.1210/clinem/dgae583. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 39172542
Effects of Exogenous GIP and GLP-2 on Bone Turnover in Individuals With Type 2 Diabetes.
Skov-Jeppesen K, Christiansen CB, Hansen LS, Windeløv JA, Hedbäck N, Gasbjerg LS, Hindsø M, Svane MS, Madsbad S, Holst JJ, Rosenkilde MM, Hartmann B. Skov-Jeppesen K, et al. Among authors: christiansen cb. J Clin Endocrinol Metab. 2024 Jun 17;109(7):1773-1780. doi: 10.1210/clinem/dgae022. J Clin Endocrinol Metab. 2024. PMID: 38217866 Free PMC article. Clinical Trial.
GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release.
Sparre-Ulrich AH, Gabe MN, Gasbjerg LS, Christiansen CB, Svendsen B, Hartmann B, Holst JJ, Rosenkilde MM. Sparre-Ulrich AH, et al. Among authors: christiansen cb. Biochem Pharmacol. 2017 May 1;131:78-88. doi: 10.1016/j.bcp.2017.02.012. Epub 2017 Feb 22. Biochem Pharmacol. 2017. PMID: 28237651 Free article.
GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats.
van der Velden WJC, Smit FX, Christiansen CB, Møller TC, Hjortø GM, Larsen O, Schiellerup SP, Bräuner-Osborne H, Holst JJ, Hartmann B, Frimurer TM, Rosenkilde MM. van der Velden WJC, et al. Among authors: christiansen cb. ACS Pharmacol Transl Sci. 2021 Jan 19;4(1):296-313. doi: 10.1021/acsptsci.0c00193. eCollection 2021 Feb 12. ACS Pharmacol Transl Sci. 2021. PMID: 33615180 Free PMC article.
112 results