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Page 1
GIP receptor antagonism eliminates paradoxical growth hormone secretion in some patients with acromegaly.
Jensen MH, Gasbjerg LS, Skov-Jeppesen K, Jacobsen JCB, Poulsen SS, Zhou C, Jakubauskaite R, Poulsen FR, Bonde C, Albarazi M, Halle B, Christiansen CB, Sanni SJ, Byberg S, Hoe B, Holst JJ, Dela F, Rasmussen AK, Knop FK, Arlien-Søborg MC, Melmed S, Jørgensen JOL, Andersen MS, Hartmann B, Klose MC, Feldt-Rasmussen U, Sparre-Ulrich AH, Rosenkilde MM. Jensen MH, et al. Among authors: sparre ulrich ah. J Clin Endocrinol Metab. 2024 Aug 22:dgae583. doi: 10.1210/clinem/dgae583. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 39172542
Acute concomitant glucose-dependent insulinotropic polypeptide receptor antagonism during glucagon-like peptide 1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity.
Stensen S, Krogh LL, Sparre-Ulrich AH, Dela F, Hartmann B, Vilsbøll T, Holst JJ, Rosenkilde MM, Christensen MB, Gasbjerg LS, Knop FK. Stensen S, et al. Among authors: sparre ulrich ah. Diabetes Obes Metab. 2022 Sep;24(9):1882-1887. doi: 10.1111/dom.14736. Epub 2022 Jun 20. Diabetes Obes Metab. 2022. PMID: 35491518 No abstract available.
Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes.
Kizilkaya HS, Sørensen KV, Kibsgaard CJ, Gasbjerg LS, Hauser AS, Sparre-Ulrich AH, Grarup N, Rosenkilde MM. Kizilkaya HS, et al. Among authors: sparre ulrich ah. Front Cell Dev Biol. 2021 Oct 25;9:749607. doi: 10.3389/fcell.2021.749607. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34760890 Free PMC article.
Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor.
Smit FX, van der Velden WJC, Kizilkaya HS, Nørskov A, Lückmann M, Hansen TN, Sparre-Ulrich AH, Qvotrup K, Frimurer TM, Rosenkilde MM. Smit FX, et al. Among authors: sparre ulrich ah. Structure. 2021 Jul 1;29(7):679-693.e6. doi: 10.1016/j.str.2021.04.001. Epub 2021 Apr 22. Structure. 2021. PMID: 33891864 Free article.
Effects of endogenous GIP in patients with type 2 diabetes.
Stensen S, Gasbjerg LS, Krogh LL, Skov-Jeppesen K, Sparre-Ulrich AH, Jensen MH, Dela F, Hartmann B, Vilsbøll T, Holst JJ, Rosenkilde MM, Christensen MB, Knop FK. Stensen S, et al. Among authors: sparre ulrich ah. Eur J Endocrinol. 2021 May 21;185(1):33-45. doi: 10.1530/EJE-21-0135. Eur J Endocrinol. 2021. PMID: 33886495
GIP and GLP-1 Receptor Antagonism During a Meal in Healthy Individuals.
Gasbjerg LS, Helsted MM, Hartmann B, Sparre-Ulrich AH, Veedfald S, Stensen S, Lanng AR, Bergmann NC, Christensen MB, Vilsbøll T, Holst JJ, Rosenkilde MM, Knop FK. Gasbjerg LS, et al. Among authors: sparre ulrich ah. J Clin Endocrinol Metab. 2020 Mar 1;105(3):dgz175. doi: 10.1210/clinem/dgz175. J Clin Endocrinol Metab. 2020. PMID: 32077470 Clinical Trial.
Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals.
Gasbjerg LS, Helsted MM, Hartmann B, Jensen MH, Gabe MBN, Sparre-Ulrich AH, Veedfald S, Stensen S, Lanng AR, Bergmann NC, Christensen MB, Vilsbøll T, Holst JJ, Rosenkilde MM, Knop FK. Gasbjerg LS, et al. Among authors: sparre ulrich ah. Diabetes. 2019 May;68(5):906-917. doi: 10.2337/db18-1123. Epub 2019 Jan 9. Diabetes. 2019. PMID: 30626611 Clinical Trial.
Human GIP(3-30)NH2 inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors.
Gabe MBN, Sparre-Ulrich AH, Pedersen MF, Gasbjerg LS, Inoue A, Bräuner-Osborne H, Hartmann B, Rosenkilde MM. Gabe MBN, et al. Among authors: sparre ulrich ah. Biochem Pharmacol. 2018 Apr;150:97-107. doi: 10.1016/j.bcp.2018.01.040. Epub 2018 Feb 3. Biochem Pharmacol. 2018. PMID: 29378179
24 results