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Page 1
Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites.
Dirkx L, Van Acker SI, Nicolaes Y, Cunha JLR, Ahmad R, Hendrickx R, Caljon B, Imamura H, Ebo DG, Jeffares DC, Sterckx YG, Maes L, Hendrickx S, Caljon G. Dirkx L, et al. PLoS Pathog. 2024 Apr 24;20(4):e1012181. doi: 10.1371/journal.ppat.1012181. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38656959 Free PMC article.
Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin.
Benramdane S, De Loose J, Filippi N, Espadinha M, Beyens O, Rymenant YV, Dirkx L, Bozdag M, Feijens PB, Augustyns K, Caljon G, De Winter H, De Meester I, Van der Veken P. Benramdane S, et al. Among authors: dirkx l. J Med Chem. 2023 Sep 28;66(18):12717-12738. doi: 10.1021/acs.jmedchem.3c00609. Epub 2023 Sep 18. J Med Chem. 2023. PMID: 37721854
Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model.
Van Breedam E, Buyle-Huybrecht T, Govaerts J, Meysman P, Bours A, Boeren M, Di Stefano J, Caers T, De Reu H, Dirkx L, Schippers J, Bartholomeus E, Lebrun M, Sadzot-Delvaux C, Rybakowska P, Alarcón-Riquelme ME, Marañón C, Laukens K, Delputte P, Ogunjimi B, Ponsaerts P. Van Breedam E, et al. Among authors: dirkx l. Front Immunol. 2023 May 23;14:1177245. doi: 10.3389/fimmu.2023.1177245. eCollection 2023. Front Immunol. 2023. PMID: 37287975 Free PMC article.
Impact of pulmonary African trypanosomes on the immunology and function of the lung.
Mabille D, Dirkx L, Thys S, Vermeersch M, Montenye D, Govaerts M, Hendrickx S, Takac P, Van Weyenbergh J, Pintelon I, Delputte P, Maes L, Pérez-Morga D, Timmermans JP, Caljon G. Mabille D, et al. Among authors: dirkx l. Nat Commun. 2022 Nov 18;13(1):7083. doi: 10.1038/s41467-022-34757-w. Nat Commun. 2022. PMID: 36400767 Free PMC article.
Reprogramming of glucocorticoid receptor function by hypoxia.
Vanderhaeghen T, Timmermans S, Watts D, Paakinaho V, Eggermont M, Vandewalle J, Wallaeys C, Van Wyngene L, Van Looveren K, Nuyttens L, Dewaele S, Vanden Berghe J, Lemeire K, De Backer J, Dirkx L, Vanden Berghe W, Caljon G, Ghesquière B, De Bosscher K, Wielockx B, Palvimo JJ, Beyaert R, Libert C. Vanderhaeghen T, et al. Among authors: dirkx l. EMBO Rep. 2022 Jan 5;23(1):e53083. doi: 10.15252/embr.202153083. Epub 2021 Oct 26. EMBO Rep. 2022. PMID: 34699114 Free PMC article.