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Nicorandil antiallodynic activity in a model of neuropathic pain is associated with the activation of ATP-dependent potassium channels and opioidergic pathways, and reduced production of cytokines and neutrophils recruitment in paw, sciatic nerve, and dorsal root ganglia.
Braga AV, Morais MÍ, Delfino DGS, Costa SOAM, Barbosa BCM, Rodrigues FF, Melo ISF, Matos RC, Castro BFM, Cunha Júnior AS, Braga TC, de Fátima Â, Coelho MM, Machado RR. Braga AV, et al. Among authors: castro bfm. Pharmacol Rep. 2024 Oct;76(5):1067-1078. doi: 10.1007/s43440-024-00640-2. Epub 2024 Aug 23. Pharmacol Rep. 2024. PMID: 39179890
RI75, a curcumin analogue, inhibits tumor necrosis factor-α and interleukin-6 production and exhibits antiallodynic and antiedematogenic activities in mice.
Costa SOAM, Rodrigues IB, Braga AV, Barbosa BCM, Silva RRL, Rodrigues FF, Melo ISF, Morais MÍ, Castro BFM, Júnior ASC, Maltarollo VG, Oliveira RB, Coelho MM, Machado RR. Costa SOAM, et al. Among authors: castro bfm. Inflammopharmacology. 2022 Apr;30(2):505-515. doi: 10.1007/s10787-021-00913-9. Epub 2022 Jan 30. Inflammopharmacology. 2022. PMID: 35094257
Intravitreal lupeol: A new potential therapeutic strategy for noninfectious uveitis.
Toledo CR, Paiva MRB, Castro BFM, Pereira VV, Cenachi SPF, Vasconcelos-Santos DV, Fialho SL, Silva-Cunha A. Toledo CR, et al. Among authors: castro bfm. Biomed Pharmacother. 2021 Nov;143:112145. doi: 10.1016/j.biopha.2021.112145. Epub 2021 Sep 7. Biomed Pharmacother. 2021. PMID: 34507119 Free article.