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Docosahexaenoic acid enhances the treatment efficacy for castration-resistant prostate cancer by inhibiting autophagy through Atg4B inhibition.
Kudo Y, Nakamura K, Tsuzuki H, Hirota K, Kawai M, Takaya D, Fukuzawa K, Honma T, Yoshino Y, Nakamura M, Shiota M, Fujimoto N, Ikari A, Endo S. Kudo Y, et al. Among authors: honma t. Arch Biochem Biophys. 2024 Oct;760:110135. doi: 10.1016/j.abb.2024.110135. Epub 2024 Aug 23. Arch Biochem Biophys. 2024. PMID: 39181384 Free article.
Structure-based development of novel substrate-type G9a inhibitors as epigenetic modulators for sickle cell disease treatment.
Nishigaya Y, Takase S, Sumiya T, Sato T, Niwa H, Sato S, Nakata A, Matsuoka S, Maemoto Y, Hashimoto N, Namie R, Honma T, Umehara T, Shirouzu M, Koyama H, Yoshida M, Ito A, Shirai F. Nishigaya Y, et al. Among authors: honma t. Bioorg Med Chem Lett. 2024 Sep 15;110:129856. doi: 10.1016/j.bmcl.2024.129856. Epub 2024 Jun 22. Bioorg Med Chem Lett. 2024. PMID: 38914346
Geometry Optimization Using the Frozen Domain and Partial Dimer Approaches in the Fragment Molecular Orbital Method: Implementation, Benchmark, and Applications to Protein Ligand-Binding Sites.
Okuwaki K, Watanabe N, Kato K, Watanabe C, Nakayama N, Kato A, Mochizuki Y, Nakano T, Honma T, Fukuzawa K. Okuwaki K, et al. Among authors: honma t. J Chem Inf Model. 2024 Dec 23;64(24):9449-9458. doi: 10.1021/acs.jcim.4c01280. Epub 2024 Dec 2. J Chem Inf Model. 2024. PMID: 39621552
710 results