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Page 1
Assessment In vitro and In silico of the Activity of Thiadiazines as NorA Efflux Pump Inhibitors.
de Araújo ACJ, Freitas PR, Araújo IM, de Oliveira Borges JA, Gonçalves SA, Paulo CLR, Almeida RS, de Moraes Oliveira-Tintino CD, de Araújo-Neto JB, Dos Santos Nascimento IJ, de Araújo-Júnior JX, da Silva-Júnior EF, de Aquino TM, Junior FJBM, Marinho ES, Dos Santos HS, de Alencar Menezes IR, Tintino SR, Coutinho HDM, Braga MFBM. de Araújo ACJ, et al. Among authors: paulo clr. Curr Microbiol. 2024 Aug 24;81(10):325. doi: 10.1007/s00284-024-03836-0. Curr Microbiol. 2024. PMID: 39182011
Characterization and Evaluation of Layered Bi2WO6 Nanosheets as a New Antibacterial Agent.
Leandro MKDNS, Moura JVB, Freire PTC, Vega ML, Lima CDL, Hidalgo ÁA, Araújo ACJ, Freitas PR, Paulo CLR, Sousa AK, Rocha JE, Leandro LMG, Silva ROMD, Cruz-Martins N, Coutinho HDM. Leandro MKDNS, et al. Among authors: paulo clr. Antibiotics (Basel). 2021 Sep 3;10(9):1068. doi: 10.3390/antibiotics10091068. Antibiotics (Basel). 2021. PMID: 34572651 Free PMC article.
Terpenes as bacterial efflux pump inhibitors: A systematic review.
Dias KJSO, Miranda GM, Bessa JR, Araújo ACJ, Freitas PR, Almeida RS, Paulo CLR, Neto JBA, Coutinho HDM, Ribeiro-Filho J. Dias KJSO, et al. Among authors: paulo clr. Front Pharmacol. 2022 Oct 13;13:953982. doi: 10.3389/fphar.2022.953982. eCollection 2022. Front Pharmacol. 2022. PMID: 36313340 Free PMC article.
Antibacterial Activity of the Essential Oil of Piper tuberculatum Jacq. Fruits against Multidrug-Resistant Strains: Inhibition of Efflux Pumps and β-Lactamase.
da Silva LYS, Paulo CLR, Moura TF, Alves DS, Pessoa RT, Araújo IM, de Morais Oliveira-Tintino CD, Tintino SR, Nonato CFA, da Costa JGM, Ribeiro-Filho J, Coutinho HDM, Kowalska G, Mitura P, Bar M, Kowalski R, Menezes IRA. da Silva LYS, et al. Among authors: paulo clr. Plants (Basel). 2023 Jun 19;12(12):2377. doi: 10.3390/plants12122377. Plants (Basel). 2023. PMID: 37376002 Free PMC article.
In vitro evaluation of the susceptibility of bacterial biofilms to hecogenin acetate.
Araújo NJS, Costa MDS, da Silva ARP, Paulo CLR, Silva CAP, Felix FJ, Oliveira-Tintino CDM, Filho JMB, de Freitas TS, Braga MFBM, Coutinho HDM, Andrade-Pinheiro JC. Araújo NJS, et al. Among authors: paulo clr. Acta Trop. 2024 May;253:107157. doi: 10.1016/j.actatropica.2024.107157. Epub 2024 Feb 22. Acta Trop. 2024. PMID: 38387772
Molecular Docking and Antibacterial Activity of Campesterol Derivatives Against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa Multiresistant Strains.
de Morais Oliveira-Tintino CD, da Silva FEF, Santiago GMP, das C L Pinto F, Pessoa ODL, da Fonseca AM, Paulo CLR, Dos Santos HS, Marinho MM, Dos Santos JL, Moura TF, Freitas PR, de Araújo ACJ, de Almeida RS, Tintino SR, Coutinho HDM. de Morais Oliveira-Tintino CD, et al. Among authors: paulo clr. Chem Biodivers. 2024 Sep 11:e202401073. doi: 10.1002/cbdv.202401073. Online ahead of print. Chem Biodivers. 2024. PMID: 39258811
Nanoencapsulation of buriti oil (Mauritia flexuosa L.f.) in porcine gelatin enhances the antioxidant potential and improves the effect on the antibiotic activity modulation.
Morais NS, Passos TS, Ramos GR, Ferreira VAF, Moreira SMG, Chaves Filho GP, Barreto APG, Leite PIP, Almeida RS, Paulo CLR, Fernandes R, Silva SÂDD, Nascimento SSDC, de Sousa Júnior FC, de Assis CF. Morais NS, et al. Among authors: paulo clr. PLoS One. 2022 Mar 18;17(3):e0265649. doi: 10.1371/journal.pone.0265649. eCollection 2022. PLoS One. 2022. PMID: 35303021 Free PMC article.
Evaluating Efflux Pump Inhibition in Staphylococcus aureus 1199B Strain Using Thiadiazine-Derived Compounds: In Vitro and In Silico Approaches.
Freitas PR, Araújo ACJ, Araújo IM, Almeida RS, Oliveira Borges JA, Lima CMG, Oliveira-Tintino CDM, Paulo CLR, Miranda GM, Araújo-Neto JB, Almeida-Bezerra JW, Nascimento IJDS, Araújo-Júnior JX, Silva-Júnior EFD, Aquino TM, Mendonca Junior FJB, Marinho ES, Santos HSD, Menezes IRA, Tintino SR, Coutinho HDM. Freitas PR, et al. Among authors: paulo clr. Biochimie. 2024 Dec 19:S0300-9084(24)00313-4. doi: 10.1016/j.biochi.2024.12.009. Online ahead of print. Biochimie. 2024. PMID: 39708974
Evaluation of inhibition and eradication of bacterial biofilm by solasodin.
da Silva ARP, Costa MDS, Araújo NJS, de Freitas TS, Paulo CLR, de Alencar MAS, Barbosa-Filho JM, Andrade-Pinheiro JC, Coutinho HDM. da Silva ARP, et al. Among authors: paulo clr. J Steroid Biochem Mol Biol. 2024 Dec 5;247:106654. doi: 10.1016/j.jsbmb.2024.106654. Online ahead of print. J Steroid Biochem Mol Biol. 2024. PMID: 39645169
Thiazine-derived compounds in inhibiting efflux pump in Staphylococcus aureus K2068, mepA gene expression, and membrane permeability alteration.
Freitas PR, de Araújo ACJ, Araújo IM, de Almeida RS, Borges JAO, Paulo CLR, Oliveira-Tintino CDM, Miranda GM, Araújo-Neto JB, Nascimento IJS, Araújo-Júnior JX, Silva JMA, Balbino TCL, Silva-Júnior EF, Aquino TM, Mendonca-Junior FJB, Marinho ES, Santos HS, Lima CMG, Obaidullah AJ, Bin Emran T, Cunha FAB, Menezes IRA, Tintino SR, Coutinho HDM. Freitas PR, et al. Among authors: paulo clr. Biomed Pharmacother. 2024 Oct;179:117291. doi: 10.1016/j.biopha.2024.117291. Epub 2024 Aug 14. Biomed Pharmacother. 2024. PMID: 39146766 Free article.