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A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors.
Vestuto V, Ciaglia T, Musella S, Di Sarno V, Smaldone G, Di Matteo F, Scala MC, Napolitano V, Miranda MR, Amodio G, Novi S, Pepe G, Basilicata MG, Gazzillo E, Pace S, Gomez-Monterrey IM, Sala M, Bifulco G, Tecce MF, Campiglia P, Ostacolo C, Lauro G, Manfra M, Bertamino A. Vestuto V, et al. Among authors: ciaglia t. J Med Chem. 2024 Aug 8;67(15):12711-12734. doi: 10.1021/acs.jmedchem.4c00718. Epub 2024 Jul 22. J Med Chem. 2024. PMID: 39038808 Free PMC article.
KCNT1 Channel Blockers: A Medicinal Chemistry Perspective.
Di Matteo F, Mancuso F, Turcio R, Ciaglia T, Stagno C, Di Chio C, Campiglia P, Bertamino A, Giofrè SV, Ostacolo C, Iraci N. Di Matteo F, et al. Among authors: ciaglia t. Molecules. 2024 Jun 20;29(12):2940. doi: 10.3390/molecules29122940. Molecules. 2024. PMID: 38931004 Free PMC article. Review.
Anticancer Therapies Based on Oxidative Damage: Lycium barbarum Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress.
Miranda MR, Basilicata MG, Vestuto V, Aquino G, Marino P, Salviati E, Ciaglia T, Domínguez-Rodríguez G, Moltedo O, Campiglia P, Pepe G, Manfra M. Miranda MR, et al. Among authors: ciaglia t. Antioxidants (Basel). 2024 Jun 11;13(6):708. doi: 10.3390/antiox13060708. Antioxidants (Basel). 2024. PMID: 38929147 Free PMC article.
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel.
Iraci N, Carotenuto L, Ciaglia T, Belperio G, Di Matteo F, Mosca I, Carleo G, Giovanna Basilicata M, Ambrosino P, Turcio R, Puzo D, Pepe G, Gomez-Monterrey I, Soldovieri MV, Di Sarno V, Campiglia P, Miceli F, Bertamino A, Ostacolo C, Taglialatela M. Iraci N, et al. Among authors: ciaglia t. J Med Chem. 2024 Jun 13;67(11):9124-9149. doi: 10.1021/acs.jmedchem.4c00268. Epub 2024 May 23. J Med Chem. 2024. PMID: 38782404 Free PMC article.
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone.
Di Micco S, Ciaglia T, Salviati E, Michela P, Kostrzewa M, Musella S, Schiano Moriello A, Di Sarno V, Smaldone G, Di Matteo F, Capolupo I, Infantino R, Bifulco G, Pepe G, Sommella EM, Kumar P, Basilicata MG, Allarà M, Sánchez-Fernández N, Aso E, Gomez-Monterrey IM, Campiglia P, Ostacolo C, Maione S, Ligresti A, Bertamino A. Di Micco S, et al. Among authors: ciaglia t. Eur J Med Chem. 2024 Apr 5;269:116298. doi: 10.1016/j.ejmech.2024.116298. Epub 2024 Mar 11. Eur J Med Chem. 2024. PMID: 38493727 Free article.
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization.
Ciaglia T, Vestuto V, Di Sarno V, Musella S, Smaldone G, Di Matteo F, Napolitano V, Miranda MR, Pepe G, Basilicata MG, Novi S, Capolupo I, Bifulco G, Campiglia P, Gomez-Monterrey I, Snoeck R, Andrei G, Manfra M, Ostacolo C, Lauro G, Bertamino A. Ciaglia T, et al. Eur J Med Chem. 2024 Feb 15;266:116128. doi: 10.1016/j.ejmech.2024.116128. Epub 2024 Jan 9. Eur J Med Chem. 2024. PMID: 38232463 Free article.
30 results