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Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization.
Kaito S, Aoyama K, Oshima M, Tsuchiya A, Miyota M, Yamashita M, Koide S, Nakajima-Takagi Y, Kozuka-Hata H, Oyama M, Yogo T, Yabushita T, Ito R, Ueno M, Hirao A, Tohyama K, Li C, Kawabata KC, Yamaguchi K, Furukawa Y, Kosako H, Yoshimi A, Goyama S, Nannya Y, Ogawa S, Agger K, Helin K, Yamazaki S, Koseki H, Doki N, Harada Y, Harada H, Nishiyama A, Nakanishi M, Iwama A. Kaito S, et al. Among authors: iwama a. Nat Commun. 2024 Aug 28;15(1):7359. doi: 10.1038/s41467-024-50498-4. Nat Commun. 2024. PMID: 39198387 Free PMC article.
Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing.
Negishi M, Saraya A, Miyagi S, Nagao K, Inagaki Y, Nishikawa M, Tajima S, Koseki H, Tsuda H, Takasaki Y, Nakauchi H, Iwama A. Negishi M, et al. Among authors: iwama a. Biochem Biophys Res Commun. 2007 Feb 23;353(4):992-8. doi: 10.1016/j.bbrc.2006.12.166. Epub 2006 Dec 29. Biochem Biophys Res Commun. 2007. PMID: 17214966
Cytokine signaling, lipid raft clustering, and HSC hibernation.
Yamazaki S, Iwama A, Morita Y, Eto K, Ema H, Nakauchi H. Yamazaki S, et al. Among authors: iwama a. Ann N Y Acad Sci. 2007 Jun;1106:54-63. doi: 10.1196/annals.1392.017. Epub 2007 Apr 18. Ann N Y Acad Sci. 2007. PMID: 17442772 Review.
324 results