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Page 1
TOPORS E3 ligase mediates resistance to hypomethylating agent cytotoxicity in acute myeloid leukemia cells.
Truong P, Shen S, Joshi S, Islam MI, Zhong L, Raftery MJ, Afrasiabi A, Alinejad-Rokny H, Nguyen M, Zou X, Bhuyan GS, Sarowar CH, Ghodousi ES, Stonehouse O, Mohamed S, Toscan CE, Connerty P, Kakadia PM, Bohlander SK, Michie KA, Larsson J, Lock RB, Walkley CR, Thoms JAI, Jolly CJ, Pimanda JE. Truong P, et al. Among authors: stonehouse o. Nat Commun. 2024 Aug 28;15(1):7360. doi: 10.1038/s41467-024-51646-6. Nat Commun. 2024. PMID: 39198401 Free PMC article.
Single-cell analyses reveal the clonal and molecular aetiology of Flt3L-induced emergency dendritic cell development.
Lin DS, Tian L, Tomei S, Amann-Zalcenstein D, Baldwin TM, Weber TS, Schreuder J, Stonehouse OJ, Rautela J, Huntington ND, Taoudi S, Ritchie ME, Hodgkin PD, Ng AP, Nutt SL, Naik SH. Lin DS, et al. Among authors: stonehouse oj. Nat Cell Biol. 2021 Mar;23(3):219-231. doi: 10.1038/s41556-021-00636-7. Epub 2021 Mar 1. Nat Cell Biol. 2021. PMID: 33649477
A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.
Amann-Zalcenstein D, Tian L, Schreuder J, Tomei S, Lin DS, Fairfax KA, Bolden JE, McKenzie MD, Jarratt A, Hilton A, Jackson JT, Di Rago L, McCormack MP, de Graaf CA, Stonehouse O, Taoudi S, Alexander WS, Nutt SL, Ritchie ME, Ng AP, Naik SH. Amann-Zalcenstein D, et al. Among authors: stonehouse o. Nat Immunol. 2020 Dec;21(12):1574-1584. doi: 10.1038/s41590-020-0799-x. Epub 2020 Oct 19. Nat Immunol. 2020. PMID: 33077975
Membrane budding is a major mechanism of in vivo platelet biogenesis.
Potts KS, Farley A, Dawson CA, Rimes J, Biben C, de Graaf C, Potts MA, Stonehouse OJ, Carmagnac A, Gangatirkar P, Josefsson EC, Anttila C, Amann-Zalcenstein D, Naik S, Alexander WS, Hilton DJ, Hawkins ED, Taoudi S. Potts KS, et al. Among authors: stonehouse oj. J Exp Med. 2020 Sep 7;217(9):e20191206. doi: 10.1084/jem.20191206. J Exp Med. 2020. PMID: 32706855 Free PMC article.