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Page 1
MAPK/ERK signaling in gliomas modulates interferon responses, T cell recruitment, microglia phenotype, and immune checkpoint blockade efficacy.
Kim KS, Zhang J, Arrieta VA, Dmello C, Grabis E, Habashy K, Duffy J, Zhao J, Gould A, Chen L, Hu J, Balyasnikova I, Chand D, Levey D, Canoll P, Zhao W, Sims PA, Rabadan R, Pandey S, Zhang B, Lee-Chang C, Heiland DH, Sonabend AM. Kim KS, et al. Among authors: lee chang c. bioRxiv [Preprint]. 2024 Sep 18:2024.09.11.612571. doi: 10.1101/2024.09.11.612571. bioRxiv. 2024. PMID: 39345374 Free PMC article. Preprint.
A covalent creatine kinase inhibitor ablates glioblastoma migration and sensitizes tumors to oxidative stress.
Katz JL, Geng Y, Billingham LK, Sadagopan NS, DeLay SL, Subbiah J, Chia TY, McManus G, Wei C, Wang H, Lin H, Silvers C, Boland LK, Wang S, Wan H, Hou D, Vázquez-Cervantes GI, Arjmandi T, Shaikh ZH, Zhang P, Ahmed AU, Tiek DM, Lee-Chang C, Chouchani ET, Miska J. Katz JL, et al. Among authors: lee chang c. Sci Rep. 2024 Sep 20;14(1):21959. doi: 10.1038/s41598-024-73051-1. Sci Rep. 2024. PMID: 39304717 Free PMC article.
B cell-based therapy produces antibodies that inhibit glioblastoma growth.
Wang S, Castro BA, Katz JL, Arrieta V, Najem H, Vazquez-Cervantes GI, Wan H, Olson IE, Hou D, Dapash M, Billingham LK, Chia TY, Wei C, Rashidi A, Platanias LC, McCortney K, Horbinski CM, Stupp R, Zhang P, Ahmed AU, Sonabend AM, Heimberger AB, Lesniak MS, Riviere-Cazaux C, Burns T, Miska J, Fischietti M, Lee-Chang C. Wang S, et al. Among authors: lee chang c. J Clin Invest. 2024 Aug 29;134(20):e177384. doi: 10.1172/JCI177384. J Clin Invest. 2024. PMID: 39207859 Free PMC article.
Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas.
Kim KS, Habashy K, Gould A, Zhao J, Najem H, Amidei C, Saganty R, Arrieta VA, Dmello C, Chen L, Zhang DY, Castro B, Billingham L, Levey D, Huber O, Marques M, Savitsky DA, Morin BM, Muzzio M, Canney M, Horbinski C, Zhang P, Miska J, Padney S, Zhang B, Rabadan R, Phillips JJ, Butowski N, Heimberger AB, Hu J, Stupp R, Chand D, Lee-Chang C, Sonabend AM. Kim KS, et al. Among authors: lee chang c. Neuro Oncol. 2024 Nov 4;26(11):2044-2060. doi: 10.1093/neuonc/noae135. Neuro Oncol. 2024. PMID: 39028616
STING agonist 8803 reprograms the immune microenvironment and increases survival in preclinical models of glioblastoma.
Najem H, Lea ST, Tripathi S, Hurley L, Chen CH, William I, Sooreshjani M, Bowie M, Hartley G, Dussold C, Pacheco S, Dmello C, Lee-Chang C, McCortney K, Steffens A, Walshon J, Ott M, Wei J, Marisetty A, Balyasnikova I, Stupp R, Lukas RV, Hu J, James CD, Horbinski CM, Lesniak MS, Ashley DM, Priebe W, Platanias LC, Curran MA, Heimberger AB. Najem H, et al. Among authors: lee chang c. J Clin Invest. 2024 Jun 17;134(12):e175033. doi: 10.1172/JCI175033. J Clin Invest. 2024. PMID: 38941297 Free PMC article.
Ultrasound-mediated delivery of doxorubicin to the brain results in immune modulation and improved responses to PD-1 blockade in gliomas.
Arrieta VA, Gould A, Kim KS, Habashy KJ, Dmello C, Vázquez-Cervantes GI, Palacín-Aliana I, McManus G, Amidei C, Gomez C, Dhiantravan S, Chen L, Zhang DY, Saganty R, Cholak ME, Pandey S, McCord M, McCortney K, Castro B, Ward R, Muzzio M, Bouchoux G, Desseaux C, Canney M, Carpentier A, Zhang B, Miska JM, Lesniak MS, Horbinski CM, Lukas RV, Stupp R, Lee-Chang C, Sonabend AM. Arrieta VA, et al. Among authors: lee chang c. Nat Commun. 2024 Jun 6;15(1):4698. doi: 10.1038/s41467-024-48326-w. Nat Commun. 2024. PMID: 38844770 Free PMC article.
Prohibitin Expression in Antigen-Presenting Cells: Implications for Inciting Trigger in CNS IgG4-Related Disease.
Najem H, Arrieta VA, Duffy J, Tripathi S, Zannikou M, Dhiantravan S, Miska J, McCortney K, Steffens A, Walshon J, Lee Chang C, Dahdaleh NS, Sonabend AM, Smith Z, Horbinski CM, Chandler J, Heimberger AB, Balyasnikova IV. Najem H, et al. Among authors: lee chang c. Ann Case Rep. 2024;9(1):1607. doi: 10.29011/2574-7754.101607. Epub 2024 Jan 25. Ann Case Rep. 2024. PMID: 38606301 Free PMC article.
The CXCL16-CXCR6 axis in glioblastoma modulates T-cell activity in a spatiotemporal context.
Chia TY, Billingham LK, Boland L, Katz JL, Arrieta VA, Shireman J, Rosas AL, DeLay SL, Zillinger K, Geng Y, Kruger J, Silvers C, Wang H, Vazquez Cervantes GI, Hou D, Wang S, Wan H, Sonabend A, Zhang P, Lee-Chang C, Miska J. Chia TY, et al. Among authors: lee chang c. Front Immunol. 2024 Jan 17;14:1331287. doi: 10.3389/fimmu.2023.1331287. eCollection 2023. Front Immunol. 2024. PMID: 38299146 Free PMC article.
Antigen-presenting B cells promote TCF-1+ PD1- stem-like CD8+ T-cell proliferation in glioblastoma.
Hou D, Wan H, Katz JL, Wang S, Castro BA, Vazquez-Cervantes GI, Arrieta VA, Dhiantravan S, Najem H, Rashidi A, Chia TY, Arjmandi T, Collado J, Billingham L, Lopez-Rosas A, Han Y, Sonabend AM, Heimberger AB, Zhang P, Miska J, Lee-Chang C. Hou D, et al. Among authors: lee chang c. Front Immunol. 2024 Jan 10;14:1295218. doi: 10.3389/fimmu.2023.1295218. eCollection 2023. Front Immunol. 2024. PMID: 38268923 Free PMC article.
60 results