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Complement activation by IgM autoantibodies linked to immune-mediated neuropathies depends on C2.
Eur J Neurol. 2025 Jan;32(1):e16541. doi: 10.1111/ene.16541. Epub 2024 Nov 15.
Eur J Neurol. 2025.
PMID: 39545641
Free PMC article.
ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes.
Vieira de Sá R, Sudria-Lopez E, Cañizares Luna M, Harschnitz O, van den Heuvel DMA, Kling S, Vonk D, Westeneng HJ, Karst H, Bloemenkamp L, Varderidou-Minasian S, Schlegel DK, Mars M, Broekhoven MH, van Kronenburg NCH, Adolfs Y, Vangoor VR, de Jongh R, Ljubikj T, Peeters L, Seeler S, Mocholi E, Basak O, Gordon D, Giuliani F, Verhoeff T, Korsten G, Calafat Pla T, Venø MT, Kjems J, Talbot K, van Es MA, Veldink JH, van den Berg LH, Zelina P, Pasterkamp RJ.
Vieira de Sá R, et al. Among authors: bloemenkamp l.
Nat Commun. 2024 Aug 29;15(1):7484. doi: 10.1038/s41467-024-51676-0.
Nat Commun. 2024.
PMID: 39209824
Free PMC article.
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IgM anti-GM2 antibodies in patients with multifocal motor neuropathy target Schwann cells and are associated with early onset.
Budding K, Bos JW, Dijkxhoorn K, de Zeeuw E, Bloemenkamp LM, Zekveld EM, Groen EJN, Jacobs BC, Huizinga R, Goedee HS, Cats EA, Leusen JHW, van den Berg LH, Hack CE, van der Pol WL.
Budding K, et al. Among authors: bloemenkamp lm.
J Neuroinflammation. 2024 Apr 17;21(1):100. doi: 10.1186/s12974-024-03090-y.
J Neuroinflammation. 2024.
PMID: 38632654
Free PMC article.
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Anti-C2 Antibody ARGX-117 Inhibits Complement in a Disease Model for Multifocal Motor Neuropathy.
Budding K, Johansen LE, Van de Walle I, Dijkxhoorn K, de Zeeuw E, Bloemenkamp LM, Bos JW, Jansen MD, Curial CAD, Silence K, de Haard H, Blanchetot C, Van de Ven L, Leusen JHW, Pasterkamp RJ, van den Berg LH, Hack CE, Boross P, van der Pol WL.
Budding K, et al. Among authors: bloemenkamp lm.
Neurol Neuroimmunol Neuroinflamm. 2021 Nov 10;9(1):e1107. doi: 10.1212/NXI.0000000000001107. Print 2022 Jan.
Neurol Neuroimmunol Neuroinflamm. 2021.
PMID: 34759020
Free PMC article.
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