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Page 1
ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes.
Vieira de Sá R, Sudria-Lopez E, Cañizares Luna M, Harschnitz O, van den Heuvel DMA, Kling S, Vonk D, Westeneng HJ, Karst H, Bloemenkamp L, Varderidou-Minasian S, Schlegel DK, Mars M, Broekhoven MH, van Kronenburg NCH, Adolfs Y, Vangoor VR, de Jongh R, Ljubikj T, Peeters L, Seeler S, Mocholi E, Basak O, Gordon D, Giuliani F, Verhoeff T, Korsten G, Calafat Pla T, Venø MT, Kjems J, Talbot K, van Es MA, Veldink JH, van den Berg LH, Zelina P, Pasterkamp RJ. Vieira de Sá R, et al. Among authors: pasterkamp rj. Nat Commun. 2024 Aug 29;15(1):7484. doi: 10.1038/s41467-024-51676-0. Nat Commun. 2024. PMID: 39209824 Free PMC article.
Getting connected in the dopamine system.
Van den Heuvel DM, Pasterkamp RJ. Van den Heuvel DM, et al. Among authors: pasterkamp rj. Prog Neurobiol. 2008 May;85(1):75-93. doi: 10.1016/j.pneurobio.2008.01.003. Epub 2008 Jan 20. Prog Neurobiol. 2008. PMID: 18304718 Review.
Axon guidance proteins: novel therapeutic targets for ALS?
Schmidt ER, Pasterkamp RJ, van den Berg LH. Schmidt ER, et al. Among authors: pasterkamp rj. Prog Neurobiol. 2009 Aug;88(4):286-301. doi: 10.1016/j.pneurobio.2009.05.004. Epub 2009 Jun 10. Prog Neurobiol. 2009. PMID: 19523502 Review.
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.
van Es MA, Veldink JH, Saris CG, Blauw HM, van Vught PW, Birve A, Lemmens R, Schelhaas HJ, Groen EJ, Huisman MH, van der Kooi AJ, de Visser M, Dahlberg C, Estrada K, Rivadeneira F, Hofman A, Zwarts MJ, van Doormaal PT, Rujescu D, Strengman E, Giegling I, Muglia P, Tomik B, Slowik A, Uitterlinden AG, Hendrich C, Waibel S, Meyer T, Ludolph AC, Glass JD, Purcell S, Cichon S, Nöthen MM, Wichmann HE, Schreiber S, Vermeulen SH, Kiemeney LA, Wokke JH, Cronin S, McLaughlin RL, Hardiman O, Fumoto K, Pasterkamp RJ, Meininger V, Melki J, Leigh PN, Shaw CE, Landers JE, Al-Chalabi A, Brown RH Jr, Robberecht W, Andersen PM, Ophoff RA, van den Berg LH. van Es MA, et al. Among authors: pasterkamp rj. Nat Genet. 2009 Oct;41(10):1083-7. doi: 10.1038/ng.442. Epub 2009 Sep 6. Nat Genet. 2009. PMID: 19734901
Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting.
Kolk SM, Gunput RA, Tran TS, van den Heuvel DM, Prasad AA, Hellemons AJ, Adolfs Y, Ginty DD, Kolodkin AL, Burbach JP, Smidt MP, Pasterkamp RJ. Kolk SM, et al. Among authors: pasterkamp rj. J Neurosci. 2009 Oct 7;29(40):12542-57. doi: 10.1523/JNEUROSCI.2521-09.2009. J Neurosci. 2009. PMID: 19812329 Free PMC article.
FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands.
Groen EJ, van Es MA, van Vught PW, Spliet WG, van Engelen-Lee J, de Visser M, Wokke JH, Schelhaas HJ, Ophoff RA, Fumoto K, Pasterkamp RJ, Dooijes D, Cuppen E, Veldink JH, van den Berg LH. Groen EJ, et al. Among authors: pasterkamp rj. Arch Neurol. 2010 Feb;67(2):224-30. doi: 10.1001/archneurol.2009.329. Arch Neurol. 2010. PMID: 20142531
MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis.
Zhou Y, Adolfs Y, Pijnappel WW, Fuller SJ, Van der Schors RC, Li KW, Sugden PH, Smit AB, Hergovich A, Pasterkamp RJ. Zhou Y, et al. Among authors: pasterkamp rj. Mol Cell Biol. 2011 Sep;31(17):3603-15. doi: 10.1128/MCB.01389-10. Epub 2011 Jul 5. Mol Cell Biol. 2011. PMID: 21730291 Free PMC article.
MICALs in control of the cytoskeleton, exocytosis, and cell death.
Zhou Y, Gunput RA, Adolfs Y, Pasterkamp RJ. Zhou Y, et al. Among authors: pasterkamp rj. Cell Mol Life Sci. 2011 Dec;68(24):4033-44. doi: 10.1007/s00018-011-0787-2. Epub 2011 Aug 6. Cell Mol Life Sci. 2011. PMID: 21822644 Free PMC article. Review.
Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility.
Messina A, Ferraris N, Wray S, Cagnoni G, Donohue DE, Casoni F, Kramer PR, Derijck AA, Adolfs Y, Fasolo A, Pasterkamp RJ, Giacobini P. Messina A, et al. Among authors: pasterkamp rj. Hum Mol Genet. 2011 Dec 15;20(24):4759-74. doi: 10.1093/hmg/ddr403. Epub 2011 Sep 8. Hum Mol Genet. 2011. PMID: 21903667 Free PMC article.
193 results