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A targetable type III immune response with increase of IL-17A expressing CD4+ T cells is associated with immunotherapy-induced toxicity in melanoma.
Dimitriou F, Cheng PF, Saltari A, Schaper-Gerhardt K, Staeger R, Haunerdinger V, Sella F, Tastanova A, Urban C, Dettwiler S, Mihic-Probst D, Matter CM, Michielin O, Gutzmer R, Long GV, Becher B, Levesque MP, Dummer R. Dimitriou F, et al. Among authors: tastanova a. Nat Cancer. 2024 Sep;5(9):1390-1408. doi: 10.1038/s43018-024-00810-4. Epub 2024 Aug 29. Nat Cancer. 2024. PMID: 39210005 Free PMC article.
COL10A1 expression distinguishes a subset of cancer-associated fibroblasts present in the stroma of high-risk basal cell carcinoma.
Esposito M, Yerly L, Shukla P, Hermes V, Sella F, Balazs Z, Lattmann E, Tastanova A, Turko P, Lang R, Kolm I, Staeger R, Kuonen F, Krauthammer M, Hafner J, Levesque MP, Restivo G. Esposito M, et al. Among authors: tastanova a. Br J Dermatol. 2024 Oct 17;191(5):775-790. doi: 10.1093/bjd/ljae258. Br J Dermatol. 2024. PMID: 38916477
ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma.
Eichhoff OM, Stoffel CI, Käsler J, Briker L, Turko P, Karsai G, Zila N, Paulitschke V, Cheng PF, Leitner A, Bileck A, Zamboni N, Irmisch A, Balazs Z, Tastanova A, Pascoal S, Johansen P, Wegmann R, Mena J, Othman A, Viswanathan VS, Wenzina J, Aloia A, Saltari A, Dzung A; TuPro Consortium; Krauthammer M, Schreiber SL, Hornemann T, Distel M, Snijder B, Dummer R, Levesque MP. Eichhoff OM, et al. Among authors: tastanova a. Cancer Res. 2023 Apr 4;83(7):1128-1146. doi: 10.1158/0008-5472.CAN-22-1826. Cancer Res. 2023. PMID: 36946761
Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells.
Amaro A, Reggiani F, Fenoglio D, Gangemi R, Tosi A, Parodi A, Banelli B, Rigo V, Mastracci L, Grillo F, Cereghetti A, Tastanova A, Ghosh A, Sallustio F, Emionite L, Daga A, Altosole T, Filaci G, Rosato A, Levesque M, Maio M, Pfeffer U, Croce M; EPigenetic Immune-oncology Consortium Airc (EPICA) consortium. Amaro A, et al. Among authors: tastanova a. J Exp Clin Cancer Res. 2023 Mar 18;42(1):67. doi: 10.1186/s13046-023-02628-x. J Exp Clin Cancer Res. 2023. PMID: 36934257 Free PMC article.
Live slow-frozen human tumor tissues viable for 2D, 3D, ex vivo cultures and single-cell RNAseq.
Restivo G, Tastanova A, Balázs Z, Panebianco F, Diepenbruck M, Ercan C, Preca BT, Hafner J, Weber WP, Kurzeder C, Vetter M, Soysal SM, Beisel C, Bentires-Alj M, Piscuoglio S, Krauthammer M, Levesque MP. Restivo G, et al. Among authors: tastanova a. Commun Biol. 2022 Oct 28;5(1):1144. doi: 10.1038/s42003-022-04025-0. Commun Biol. 2022. PMID: 36307545 Free PMC article.
An Optimized Tissue Dissociation Protocol for Single-Cell RNA Sequencing Analysis of Fresh and Cultured Human Skin Biopsies.
Burja B, Paul D, Tastanova A, Edalat SG, Gerber R, Houtman M, Elhai M, Bürki K, Staeger R, Restivo G, Lang R, Sodin-Semrl S, Lakota K, Tomšič M, Levesque MP, Distler O, Rotar Ž, Robinson MD, Frank-Bertoncelj M. Burja B, et al. Among authors: tastanova a. Front Cell Dev Biol. 2022 Apr 28;10:872688. doi: 10.3389/fcell.2022.872688. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35573685 Free PMC article.
14 results