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395 results

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Page 1
Identification of a specific APOE transcript and functional elements associated with Alzheimer's disease.
Chen Q, Aguirre L, Liang G, Zhao H, Dong T, Borrego F, de Rojas I, Hu Q, Reyes C, Su LY, Zhang B, Lechleiter JD, Göring HHH, De Jager PL, Kleinman JE, Hyde TM, Li PP, Ruiz A, Weinberger DR, Seshadri S, Ma L. Chen Q, et al. Among authors: kleinman je. Mol Neurodegener. 2024 Aug 29;19(1):63. doi: 10.1186/s13024-024-00751-7. Mol Neurodegener. 2024. PMID: 39210471 Free PMC article.
Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood.
Daskalakis NP, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, DiPietro CP, Tsatsani I, Chen CY, Pernia CD, Soliva-Estruch M, Arasappan D, Bharadwaj RA, Collado-Torres L, Wuchty S, Alvarez VE, Dammer EB, Deep-Soboslay A, Duong DM, Eagles N, Huber BR, Huuki L, Holstein VL, Logue MW, Lugenbühl JF, Maihofer AX, Miller MW, Nievergelt CM, Pertea G, Ross D, Sendi MSE, Sun BB, Tao R, Tooke J, Wolf EJ, Zeier Z; PTSD Working Group of Psychiatric Genomics Consortium**; Berretta S, Champagne FA, Hyde T, Seyfried NT, Shin JH, Weinberger DR, Nemeroff CB, Kleinman JE, Ressler KJ; PTSD Working Group of Psychiatric Genomics Consortium. Daskalakis NP, et al. Among authors: kleinman je. Science. 2024 May 24;384(6698):eadh3707. doi: 10.1126/science.adh3707. Epub 2024 May 24. Science. 2024. PMID: 38781393
Individual variation in the emergence of anterior-to-posterior neural fates from human pluripotent stem cells.
Kim SK, Seo S, Stein-O'Brien G, Jaishankar A, Ogawa K, Micali N, Luria V, Karger A, Wang Y, Kim H, Hyde TM, Kleinman JE, Voss T, Fertig EJ, Shin JH, Bürli R, Cross AJ, Brandon NJ, Weinberger DR, Chenoweth JG, Hoeppner DJ, Sestan N, Colantuoni C, McKay RD. Kim SK, et al. Among authors: kleinman je. Stem Cell Reports. 2024 Sep 10;19(9):1336-1350. doi: 10.1016/j.stemcr.2024.07.004. Epub 2024 Aug 15. Stem Cell Reports. 2024. PMID: 39151428 Free PMC article.
Influence of Alzheimer's disease related neuropathology on local microenvironment gene expression in the human inferior temporal cortex.
Kwon SH, Parthiban S, Tippani M, Divecha HR, Eagles NJ, Lobana JS, Williams SR, Mak M, Bharadwaj RA, Kleinman JE, Hyde TM, Page SC, Hicks SC, Martinowich K, Maynard KR, Collado-Torres L. Kwon SH, et al. Among authors: kleinman je. GEN Biotechnol. 2023 Oct;2(5):399-417. doi: 10.1089/genbio.2023.0019. Epub 2023 Oct 16. GEN Biotechnol. 2023. PMID: 39329069 Free PMC article.
Alcohol Use Disorder-Associated DNA Methylation in the Nucleus Accumbens and Dorsolateral Prefrontal Cortex.
White JD, Minto MS, Willis C, Quach BC, Han S, Tao R, Deep-Soboslay A, Zillich L, Witt SH, Spanagel R, Hansson AC, Clark SL, van den Oord EJCG, Hyde TM, Mayfield RD, Webb BT, Johnson EO, Kleinman JE, Bierut LJ, Hancock DB. White JD, et al. Among authors: kleinman je. Biol Psychiatry Glob Open Sci. 2024 Aug 13;4(6):100375. doi: 10.1016/j.bpsgos.2024.100375. eCollection 2024 Nov. Biol Psychiatry Glob Open Sci. 2024. PMID: 39399155 Free PMC article.
Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts.
Katrinli S, Wani AH, Maihofer AX, Ratanatharathorn A, Daskalakis NP, Montalvo-Ortiz J, Núñez-Ríos DL, Zannas AS, Zhao X, Aiello AE, Ashley-Koch AE, Avetyan D, Baker DG, Beckham JC, Boks MP, Brick LA, Bromet E, Champagne FA, Chen CY, Dalvie S, Dennis MF, Fatumo S, Fortier C, Galea S, Garrett ME, Geuze E, Grant G, Michael A Hauser, Hayes JP, Hemmings SM, Huber BR, Jajoo A, Jansen S, Kessler RC, Kimbrel NA, King AP, Kleinman JE, Koen N, Koenen KC, Kuan PF, Liberzon I, Linnstaedt SD, Lori A, Luft BJ, Luykx JJ, Marx CE, McLean SA, Mehta D, Milberg W, Miller MW, Mufford MS, Musanabaganwa C, Mutabaruka J, Mutesa L, Nemeroff CB, Nugent NR, Orcutt HK, Qin XJ, Rauch SAM, Ressler KJ, Risbrough VB, Rutembesa E, Rutten BPF, Seedat S, Stein DJ, Stein MB, Toikumo S, Ursano RJ, Uwineza A, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Young RM, Zhao Y, van den Heuvel LL; PGC-PTSD Epigenetics Workgroup, PsychENCODE PTSD Brainomics Project, Traumatic Stress Brain Research Group; Uddin M, Nievergelt CM, Smith AK, Logue MW. Katrinli S, et al. Among authors: kleinman je. medRxiv [Preprint]. 2024 Jul 15:2024.07.15.24310422. doi: 10.1101/2024.07.15.24310422. medRxiv. 2024. PMID: 39072012 Free PMC article. Preprint.
Transcriptomic diversity of amygdalar subdivisions across humans and nonhuman primates.
Totty MS, Juanes RC, Bach SV, Ameur LB, Valentine MR, Simons E, Romac M, Trinh H, Henderson K, Del Rosario I, Tippani M, Miller RA, Kleinman JE, Page SC, Saunders A, Hyde TM, Martinowich K, Hicks SC, Costa VD. Totty MS, et al. Among authors: kleinman je. bioRxiv [Preprint]. 2024 Oct 18:2024.10.18.618721. doi: 10.1101/2024.10.18.618721. bioRxiv. 2024. PMID: 39463931 Free PMC article. Preprint.
Gene expression differences associated with alcohol use disorder in human brain.
Willis C, White JD, Minto MS, Quach BC, Han S, Tao R, Shin JH, Deep-Soboslay A, Hyde TM, Mayfield RD, Webb BT, Johnson EO, Kleinman JE, Bierut LJ, Hancock DB. Willis C, et al. Among authors: kleinman je. Mol Psychiatry. 2024 Oct 12. doi: 10.1038/s41380-024-02777-1. Online ahead of print. Mol Psychiatry. 2024. PMID: 39394458
Smoking-informed methylation and expression QTLs in human brain and colocalization with smoking-associated genetic loci.
Carnes MU, Quach BC, Zhou L, Han S, Tao R, Mandal M, Deep-Soboslay A, Marks JA, Page GP, Maher BS, Jaffe AE, Won H, Bierut LJ, Hyde TM, Kleinman JE, Johnson EO, Hancock DB. Carnes MU, et al. Among authors: kleinman je. Neuropsychopharmacology. 2024 Oct;49(11):1749-1757. doi: 10.1038/s41386-024-01885-4. Epub 2024 Jun 4. Neuropsychopharmacology. 2024. PMID: 38830989 Free PMC article.
395 results