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Page 1
Advanced piperazine-containing inhibitors target microbial β-glucuronidases linked to gut toxicity.
Graboski AL, Simpson JB, Pellock SJ, Mehta N, Creekmore BC, Ariyarathna Y, Bhatt AP, Jariwala PB, Sekela JJ, Kowalewski ME, Barker NK, Mordant AL, Borlandelli VB, Overkleeft H, Herring LE, Jin J, I James L, Redinbo MR. Graboski AL, et al. Among authors: ariyarathna y. RSC Chem Biol. 2024 Jul 16;5(9):853-865. doi: 10.1039/d4cb00058g. eCollection 2024 Aug 28. RSC Chem Biol. 2024. PMID: 39211470 Free PMC article.
Gut Microbial β-Glucuronidase Inhibition via Catalytic Cycle Interception.
Pellock SJ, Creekmore BC, Walton WG, Mehta N, Biernat KA, Cesmat AP, Ariyarathna Y, Dunn ZD, Li B, Jin J, James LI, Redinbo MR. Pellock SJ, et al. Among authors: ariyarathna y. ACS Cent Sci. 2018 Jul 25;4(7):868-879. doi: 10.1021/acscentsci.8b00239. Epub 2018 Jul 12. ACS Cent Sci. 2018. PMID: 30062115 Free PMC article.
Multicomponent decarboxylative allylations.
Ariyarathna Y, Tunge JA. Ariyarathna Y, et al. Chem Commun (Camb). 2014 Nov 21;50(90):14049-52. doi: 10.1039/c4cc07253g. Chem Commun (Camb). 2014. PMID: 25269477
Decarboxylative benzylations of alkynes and ketones.
Torregrosa RR, Ariyarathna Y, Chattopadhyay K, Tunge JA. Torregrosa RR, et al. Among authors: ariyarathna y. J Am Chem Soc. 2010 Jul 14;132(27):9280-2. doi: 10.1021/ja1035557. J Am Chem Soc. 2010. PMID: 20565096 Free PMC article.