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Surgical window of opportunity trial reveals mechanisms of response and resistance to navtemadlin (KRT-232) in patients with recurrent glioblastoma.
Rendo V, Lee EQ, Bossi C, Khuu N, Rudek MA, Pal S, Reynolds ARN, Fassinou ACR, Ayoub G, Lapinskas E, Pisano W, Jeang J, Stopka SA, Regan MS, Spetz J, Desai A, Lieberman F, Fisher JD, Pelton K, Huang RY, Nabors LB, Holdhoff M, Danda N, Strowd R, Desideri S, Walbert T, Ye X, Agar NYR, Grossman SA, Alexander BM, Wen PY, Ligon KL, Beroukhim R. Rendo V, et al. Among authors: holdhoff m. medRxiv [Preprint]. 2024 Aug 14:2024.08.12.24311893. doi: 10.1101/2024.08.12.24311893. medRxiv. 2024. PMID: 39211865 Free PMC article. Preprint.
Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma.
Mellinghoff IK, van den Bent MJ, Blumenthal DT, Touat M, Peters KB, Clarke J, Mendez J, Yust-Katz S, Welsh L, Mason WP, Ducray F, Umemura Y, Nabors B, Holdhoff M, Hottinger AF, Arakawa Y, Sepulveda JM, Wick W, Soffietti R, Perry JR, Giglio P, de la Fuente M, Maher EA, Schoenfeld S, Zhao D, Pandya SS, Steelman L, Hassan I, Wen PY, Cloughesy TF; INDIGO Trial Investigators. Mellinghoff IK, et al. Among authors: holdhoff m. N Engl J Med. 2023 Aug 17;389(7):589-601. doi: 10.1056/NEJMoa2304194. Epub 2023 Jun 4. N Engl J Med. 2023. PMID: 37272516 Free PMC article. Clinical Trial.
Molecular Testing for the World Health Organization Classification of Central Nervous System Tumors: A Review.
Horbinski C, Solomon DA, Lukas RV, Packer RJ, Brastianos P, Wen PY, Snuderl M, Berger MS, Chang S, Fouladi M, Phillips JJ, Nabors B, Brat DJ, Huse JT, Aldape K, Sarkaria JN, Holdhoff M, Burns TC, Peters KB, Mellinghoff IK, Arons D, Galanis E. Horbinski C, et al. Among authors: holdhoff m. JAMA Oncol. 2024 Dec 26. doi: 10.1001/jamaoncol.2024.5506. Online ahead of print. JAMA Oncol. 2024. PMID: 39724142
Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM.
Pearlman AH, Wang Y, Kalluri A, Parker M, Cohen JD, Dudley J, Rincon-Torroella J, Xia Y, Gensler R, Horwitz MA, Theodore J, Dobbyn L, Popoli M, Ptak J, Silliman N, Judge K, Groves M, Jackson CM, Jackson EM, Jallo GI, Lim M, Luciano M, Mukherjee D, Naidoo J, Rozati S, Sterling CH, Weingart J, Koschmann C, Mansoori A, Glantz M, Kamson D, Schreck KC, Pardo CA, Holdhoff M, Paul S, Kinzler KW, Papadopoulos N, Vogelstein B, Douville C, Bettegowda C. Pearlman AH, et al. Among authors: holdhoff m. medRxiv [Preprint]. 2024 Dec 4:2024.12.02.24318303. doi: 10.1101/2024.12.02.24318303. medRxiv. 2024. PMID: 39677487 Free PMC article. Preprint.
NF1 expression profiling in IDH-wildtype glioblastoma: genomic associations and survival outcomes.
Chang M, Sherief M, Ioannou M, Chinnasamy V, Chen L, Frost M, Mattson-Hoss M, Sarnoff H, Kamson DO, Holdhoff M, Mukherjee D, Bettegowda C, Rincon-Torroella J, Croog V, Huang P, Rodriguez FJ, Lucas CG, Schreck KC. Chang M, et al. Among authors: holdhoff m. Acta Neuropathol Commun. 2024 Oct 29;12(1):172. doi: 10.1186/s40478-024-01875-z. Acta Neuropathol Commun. 2024. PMID: 39472976 Free PMC article.
Impact of upfront adjuvant chemoradiation on survival in patients with molecularly defined oligodendroglioma: the benefits of PCV over TMZ.
Rincon-Torroella J, Rakovec M, Kalluri AL, Jiang K, Weber-Levine C, Parker M, Raj D, Materi J, Sepehri S, Ferres A, Schreck KC, Aldecoa I, Lucas CG, Sair HI, Redmond KJ, Holdhoff M, Weingart J, Brem H, Sánchez JJG, Ye X, Bettegowda C. Rincon-Torroella J, et al. Among authors: holdhoff m. J Neurooncol. 2025 Jan;171(1):35-45. doi: 10.1007/s11060-024-04829-6. Epub 2024 Oct 9. J Neurooncol. 2025. PMID: 39382617
Lisavanbulin (BAL101553), a novel microtubule inhibitor, plus radiation in patients with newly diagnosed, MGMT promoter unmethylated glioblastoma.
Holdhoff M, Ye X, Strowd RE, Nabors B, Walbert T, Lieberman FS, Bagley SJ, Fiveash JB, Fisher JD, Desideri S, Surakus T, Engelhardt M, Kaindl T, Lane HA, Litherland K, Grossman SA, Kleinberg LR. Holdhoff M, et al. Neurooncol Adv. 2024 Aug 28;6(1):vdae150. doi: 10.1093/noajnl/vdae150. eCollection 2024 Jan-Dec. Neurooncol Adv. 2024. PMID: 39371261 Free PMC article.
Radiation immunodynamics in patients with glioblastoma receiving chemoradiation.
Sloan L, Sen R, Liu C, Doucet M, Blosser L, Katulis L, Kamson DO, Grossman S, Holdhoff M, Redmond KJ, Quon H, Lim M, Eberhart C, Pardoll DM, Hu C, Ganguly S, Kleinberg LR. Sloan L, et al. Among authors: holdhoff m. Front Immunol. 2024 Sep 13;15:1438044. doi: 10.3389/fimmu.2024.1438044. eCollection 2024. Front Immunol. 2024. PMID: 39346903 Free PMC article.
The immune response to Covid-19 mRNA vaccination among Lymphoma patients receiving anti-CD20 treatment.
Komlodi-Pasztor E, Escarra-Senmarti M, Bazer DA, Bhatnagar A, Perez Heydrich CA, Messmer M, Ambinder RF, Gladstone DE, Clayton L, Goodrich A, Schoch L, Wagner-Johnston N, VandenBussche CJ, Huang P, Holdhoff M, Rosario M. Komlodi-Pasztor E, et al. Among authors: holdhoff m. Front Immunol. 2024 Sep 4;15:1433442. doi: 10.3389/fimmu.2024.1433442. eCollection 2024. Front Immunol. 2024. PMID: 39295862 Free PMC article.
115 results