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Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib.
Zhang X, Rameika N, Zhong L, Rendo V, Veanes M, Kundu S, Nuciforo S, Dupuis J, Al Azhar M, Tsiara I, Seeburger P, Al Nassralla S, Ljungström V, Svensson R, Stoimenov I, Artursson P, Heim MH, Globisch D, Sjöblom T. Zhang X, et al. Among authors: rendo v. EBioMedicine. 2024 Nov;109:105368. doi: 10.1016/j.ebiom.2024.105368. Epub 2024 Oct 4. EBioMedicine. 2024. PMID: 39368455 Free PMC article.
Surgical window of opportunity trial reveals mechanisms of response and resistance to navtemadlin (KRT-232) in patients with recurrent glioblastoma.
Rendo V, Lee EQ, Bossi C, Khuu N, Rudek MA, Pal S, Reynolds ARN, Fassinou ACR, Ayoub G, Lapinskas E, Pisano W, Jeang J, Stopka SA, Regan MS, Spetz J, Desai A, Lieberman F, Fisher JD, Pelton K, Huang RY, Nabors LB, Holdhoff M, Danda N, Strowd R, Desideri S, Walbert T, Ye X, Agar NYR, Grossman SA, Alexander BM, Wen PY, Ligon KL, Beroukhim R. Rendo V, et al. medRxiv [Preprint]. 2024 Aug 14:2024.08.12.24311893. doi: 10.1101/2024.08.12.24311893. medRxiv. 2024. PMID: 39211865 Free PMC article. Preprint.
Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening.
Gezelius H, Enblad AP, Lundmark A, Åberg M, Blom K, Rudfeldt J, Raine A, Harila A, Rendo V, Heinäniemi M, Andersson C, Nordlund J. Gezelius H, et al. Among authors: rendo v. NAR Genom Bioinform. 2024 Jan 29;6(1):lqae001. doi: 10.1093/nargab/lqae001. eCollection 2024 Mar. NAR Genom Bioinform. 2024. PMID: 38288374 Free PMC article.
Cancer aneuploidies are shaped primarily by effects on tumour fitness.
Shih J, Sarmashghi S, Zhakula-Kostadinova N, Zhang S, Georgis Y, Hoyt SH, Cuoco MS, Gao GF, Spurr LF, Berger AC, Ha G, Rendo V, Shen H, Meyerson M, Cherniack AD, Taylor AM, Beroukhim R. Shih J, et al. Among authors: rendo v. Nature. 2023 Jul;619(7971):793-800. doi: 10.1038/s41586-023-06266-3. Epub 2023 Jun 28. Nature. 2023. PMID: 37380777 Free PMC article.
PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation.
Khadka P, Reitman ZJ, Lu S, Buchan G, Gionet G, Dubois F, Carvalho DM, Shih J, Zhang S, Greenwald NF, Zack T, Shapira O, Pelton K, Hartley R, Bear H, Georgis Y, Jarmale S, Melanson R, Bonanno K, Schoolcraft K, Miller PG, Condurat AL, Gonzalez EM, Qian K, Morin E, Langhnoja J, Lupien LE, Rendo V, Digiacomo J, Wang D, Zhou K, Kumbhani R, Guerra Garcia ME, Sinai CE, Becker S, Schneider R, Vogelzang J, Krug K, Goodale A, Abid T, Kalani Z, Piccioni F, Beroukhim R, Persky NS, Root DE, Carcaboso AM, Ebert BL, Fuller C, Babur O, Kieran MW, Jones C, Keshishian H, Ligon KL, Carr SA, Phoenix TN, Bandopadhayay P. Khadka P, et al. Among authors: rendo v. Nat Commun. 2022 Feb 1;13(1):604. doi: 10.1038/s41467-022-28198-8. Nat Commun. 2022. PMID: 35105861 Free PMC article.
TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.
Parnandi N, Rendo V, Cui G, Botuyan MV, Remisova M, Nguyen H, Drané P, Beroukhim R, Altmeyer M, Mer G, Chowdhury D. Parnandi N, et al. Among authors: rendo v. Mol Cell. 2021 Jun 17;81(12):2583-2595.e6. doi: 10.1016/j.molcel.2021.03.039. Epub 2021 May 6. Mol Cell. 2021. PMID: 33961797 Free PMC article.
Women in cancer research and oncology.
Joyce J, Wakelee H, Davis MB, Teo SH, Bell S, Rendo V. Joyce J, et al. Among authors: rendo v. Cancer Cell. 2021 Mar 8;39(3):285-287. doi: 10.1016/j.ccell.2021.02.008. Cancer Cell. 2021. PMID: 33689700 Free article.
19 results