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Genetic Silencing of AKT Induces Melanoma Cell Death via mTOR Suppression.
Parkman GL, Turapov T, Kircher DA, Burnett WJ, Stehn CM, O'Toole K, Culver KM, Chadwick AT, Elmer RC, Flaherty R, Stanley KA, Foth M, Lum DH, Judson-Torres RL, Friend JE, VanBrocklin MW, McMahon M, Holmen SL. Parkman GL, et al. Mol Cancer Ther. 2024 Mar 4;23(3):301-315. doi: 10.1158/1535-7163.MCT-23-0474. Mol Cancer Ther. 2024. PMID: 37931033 Free PMC article.
Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer.
Ghazi PC, O'Toole KT, Srinivas Boggaram S, Scherzer MT, Silvis MR, Zhang Y, Bogdan M, Smith BD, Lozano G, Flynn DL, Snyder EL, Kinsey CG, McMahon M. Ghazi PC, et al. Among authors: o toole kt. bioRxiv [Preprint]. 2024 Jun 17:2024.02.06.579200. doi: 10.1101/2024.02.06.579200. bioRxiv. 2024. Update in: Elife. 2024 Aug 30;13:RP96992. doi: 10.7554/eLife.96992 PMID: 38370808 Free PMC article. Updated. Preprint.