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Page 1
Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells.
Wang K, Coutifaris P, Brocks D, Wang G, Azar T, Solis S, Nandi A, Anderson S, Han N, Manne S, Kiner E, Sachar C, Lucas M, George S, Yan PK, Kier MW, Laughlin AI, Kothari S, Giles J, Mathew D, Ghinnagow R, Alanio C, Flowers A, Xu W, Tenney DJ, Xu X, Amaravadi RK, Karakousis GC, Schuchter LM, Buggert M, Oldridge D, Minn AJ, Blank C, Weber JS, Mitchell TC, Farwell MD, Herati RS, Huang AC. Wang K, et al. Among authors: minn aj. Cancer Cell. 2024 Sep 9;42(9):1582-1597.e10. doi: 10.1016/j.ccell.2024.08.007. Epub 2024 Aug 29. Cancer Cell. 2024. PMID: 39214097
Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer.
Memon D, Schoenfeld AJ, Ye D, Fromm G, Rizvi H, Zhang X, Keddar MR, Mathew D, Yoo KJ, Qiu J, Lihm J, Miriyala J, Sauter JL, Luo J, Chow A, Bhanot UK, McCarthy C, Vanderbilt CM, Liu C, Abu-Akeel M, Plodkowski AJ, McGranahan N, Łuksza M, Greenbaum BD, Merghoub T, Achour I, Barrett JC, Stewart R, Beltrao P, Schreiber TH, Minn AJ, Miller ML, Hellmann MD. Memon D, et al. Among authors: minn aj. Cancer Cell. 2024 Feb 12;42(2):209-224.e9. doi: 10.1016/j.ccell.2023.12.013. Epub 2024 Jan 11. Cancer Cell. 2024. PMID: 38215748 Free article.
Targeting peptide antigens using a multiallelic MHC I-binding system.
Du H, Mallik L, Hwang D, Sun Y, Kaku C, Hoces D, Sun SM, Ghinnagow R, Carro SD, Phan HAT, Gupta S, Blackson W, Lee H, Choe CA, Dersh D, Liu J, Bell B, Yang H, Papadaki GF, Young MC, Zhou E, El Nesr G, Goli KD, Eisenlohr LC, Minn AJ, Hernandez-Lopez RA, Jardine JG, Sgourakis NG, Huang PS. Du H, et al. Among authors: minn aj. Nat Biotechnol. 2024 Dec 13. doi: 10.1038/s41587-024-02505-8. Online ahead of print. Nat Biotechnol. 2024. PMID: 39672954
Isolation of Epithelial and Stromal Cells from Colon Tissues in Homeostasis and Under Inflammatory Conditions.
Morral C, Ghinnagow R, Karakasheva T, Zhou Y, Thadi A, Li N, Yoshor B, Soto GE, Chen CH, Aleynick D, Weinbrom S, Fulton M, Uzun Y, Bewtra M, Kelsen JR, Lengner CJ, Tan K, Minn AJ, Hamilton KE. Morral C, et al. Among authors: minn aj. Bio Protoc. 2023 Sep 20;13(18):e4825. doi: 10.21769/BioProtoc.4825. eCollection 2023 Sep 20. Bio Protoc. 2023. PMID: 37753470 Free PMC article.
TLR priming licenses NAIP inflammasome activation by immunoevasive ligands.
Grayczyk JP, Liu L, Egan MS, Aunins E, Wynosky-Dolfi MA, Canna SW, Minn AJ, Shin S, Brodsky IE. Grayczyk JP, et al. Among authors: minn aj. Proc Natl Acad Sci U S A. 2024 Nov 26;121(48):e2412700121. doi: 10.1073/pnas.2412700121. Epub 2024 Nov 18. Proc Natl Acad Sci U S A. 2024. PMID: 39556752
Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy.
Lim TL, Morral C, Verginadis II, Kim K, Luo L, Foley CJ, Kim MM, Li N, Yoshor B, Njah K, Putt M, Oliaei Motlagh SA, Velalopoulou A, Chowdhury P, Bicher S, Goia D, Lengner CJ, Wrana JL, Koumenis C, Minn AJ. Lim TL, et al. Among authors: minn aj. bioRxiv [Preprint]. 2024 Aug 19:2024.08.16.608284. doi: 10.1101/2024.08.16.608284. bioRxiv. 2024. PMID: 39229237 Free PMC article. Preprint.
Combined JAK inhibition and PD-1 immunotherapy for non-small cell lung cancer patients.
Mathew D, Marmarelis ME, Foley C, Bauml JM, Ye D, Ghinnagow R, Ngiow SF, Klapholz M, Jun S, Zhang Z, Zorc R, Davis CW, Diehn M, Giles JR, Huang AC, Hwang WT, Zhang NR, Schoenfeld AJ, Carpenter EL, Langer CJ, Wherry EJ, Minn AJ. Mathew D, et al. Among authors: minn aj. Science. 2024 Jun 21;384(6702):eadf1329. doi: 10.1126/science.adf1329. Epub 2024 Jun 21. Science. 2024. PMID: 38900877 Free PMC article. Clinical Trial.
p53 promotes revival stem cells in the regenerating intestine after severe radiation injury.
Morral C, Ayyaz A, Kuo HC, Fink M, Verginadis II, Daniel AR, Burner DN, Driver LM, Satow S, Hasapis S, Ghinnagow R, Luo L, Ma Y, Attardi LD, Koumenis C, Minn AJ, Wrana JL, Lee CL, Kirsch DG. Morral C, et al. Among authors: minn aj. Nat Commun. 2024 Apr 8;15(1):3018. doi: 10.1038/s41467-024-47124-8. Nat Commun. 2024. PMID: 38589357 Free PMC article.
79 results