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Simvastatin exerts neuroprotective effects post-stroke by ameliorating endoplasmic reticulum stress and regulating autophagy/apoptosis balance through pAMPK/LC3B/ LAMP2 axis.
Ghosh B, Datta A, Gupta V, Sodnar B, Sarkar A, Singh U, Raut S, Suthar P, Thongire V, Sarmah D, Kaur H, Borah A, Saraf S, Bhattacharya P. Ghosh B, et al. Among authors: thongire v. Exp Neurol. 2024 Nov;381:114940. doi: 10.1016/j.expneurol.2024.114940. Epub 2024 Aug 28. Exp Neurol. 2024. PMID: 39214348
Cardiolipin-Mediated Alleviation of Mitochondrial Dysfunction Is a Neuroprotective Effect of Statin in Animal Model of Ischemic Stroke.
Sarmah D, Sarkar A, Datta A, Ghosh B, Rana N, Sahu S, Gupta V, Thongire V, Chaudhary A, Vadak N, Kaur H, Raut S, Singh U, Borah A, Bhattacharya P. Sarmah D, et al. Among authors: thongire v. ACS Chem Neurosci. 2023 Feb 15;14(4):709-724. doi: 10.1021/acschemneuro.2c00645. Epub 2023 Jan 27. ACS Chem Neurosci. 2023. PMID: 36706354