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Lipid-polymer nanoparticles to probe the native-like environment of intramembrane rhomboid protease GlpG and its activity.
Nat Commun. 2024 Aug 30;15(1):7533. doi: 10.1038/s41467-024-51989-0.
Nat Commun. 2024.
PMID: 39215029
Free PMC article.
The opening dynamics of the lateral gate regulates the activity of rhomboid proteases.
Bohg C, Öster C, Türkaydin B, Lisurek M, Sanchez-Carranza P, Lange S, Utesch T, Sun H, Lange A.
Bohg C, et al.
Sci Adv. 2023 Jul 21;9(29):eadh3858. doi: 10.1126/sciadv.adh3858. Epub 2023 Jul 19.
Sci Adv. 2023.
PMID: 37467320
Free PMC article.
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A combination of solid-state NMR and MD simulations reveals the binding mode of a rhomboid protease inhibitor.
Bohg C, Öster C, Utesch T, Bischoff S, Lange S, Shi C, Sun H, Lange A.
Bohg C, et al.
Chem Sci. 2021 Sep 1;12(38):12754-12762. doi: 10.1039/d1sc02146j. eCollection 2021 Oct 6.
Chem Sci. 2021.
PMID: 34703562
Free PMC article.
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Structure and Dynamics of the Rhomboid Protease GlpG in Liposomes Studied by Solid-State NMR.
Shi C, Öster C, Bohg C, Li L, Lange S, Chevelkov V, Lange A.
Shi C, et al. Among authors: bohg c.
J Am Chem Soc. 2019 Oct 30;141(43):17314-17321. doi: 10.1021/jacs.9b08952. Epub 2019 Oct 16.
J Am Chem Soc. 2019.
PMID: 31603315
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