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Synthetic lethality of combined ULK1 defection and p53 restoration induce pyroptosis by directly upregulating GSDME transcription and cleavage activation through ROS/NLRP3 signaling.
Chen W, Yang KB, Zhang YZ, Lin ZS, Chen JW, Qi SF, Wu CF, Feng GK, Yang DJ, Chen M, Zhu XF, Li X. Chen W, et al. Among authors: li x. J Exp Clin Cancer Res. 2024 Aug 30;43(1):248. doi: 10.1186/s13046-024-03168-8. J Exp Clin Cancer Res. 2024. PMID: 39215364 Free PMC article.
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