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Page 1
Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides.
Kocek H, Chalupská D, Dejmek M, Dvořáková A, Zgarbová M, Šála M, Chalupský K, Krafčíková P, Otava T, Drexler M, Procházková E, Klepetářová B, Štefek M, Kozic J, Mertlíková-Kaiserová H, Boura E, Weber J, Nencka R. Kocek H, et al. Among authors: prochazkova e. RSC Med Chem. 2024 Aug 1;15(10):3469-76. doi: 10.1039/d4md00422a. Online ahead of print. RSC Med Chem. 2024. PMID: 39220762 Free PMC article.
Synthesis of novel purine-based coxsackievirus inhibitors bearing polycylic substituents at the N-9 position.
Dejmek M, Sála M, Plačková P, Hřebabecký H, Mascarell Borredà L, Neyts J, Dračínský M, Procházková E, Jansa P, Leyssen P, Mertlíková-Kaiserová H, Nencka R. Dejmek M, et al. Among authors: prochazkova e. Arch Pharm (Weinheim). 2014 Jul;347(7):478-85. doi: 10.1002/ardp.201300431. Epub 2014 Mar 20. Arch Pharm (Weinheim). 2014. PMID: 24652670
Norbornane-based nucleoside and nucleotide analogues locked in North conformation.
Dejmek M, Šála M, Hřebabecký H, Dračínský M, Procházková E, Chalupská D, Klíma M, Plačková P, Hájek M, Andrei G, Naesens L, Leyssen P, Neyts J, Balzarini J, Boura E, Nencka R. Dejmek M, et al. Among authors: prochazkova e. Bioorg Med Chem. 2015 Jan 1;23(1):184-91. doi: 10.1016/j.bmc.2014.11.011. Epub 2014 Nov 15. Bioorg Med Chem. 2015. PMID: 25435471
Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action.
Mejdrová I, Chalupská D, Kögler M, Šála M, Plačková P, Baumlová A, Hřebabecký H, Procházková E, Dejmek M, Guillon R, Strunin D, Weber J, Lee G, Birkus G, Mertlíková-Kaiserová H, Boura E, Nencka R. Mejdrová I, et al. Among authors: prochazkova e. J Med Chem. 2015 May 14;58(9):3767-93. doi: 10.1021/acs.jmedchem.5b00499. Epub 2015 May 4. J Med Chem. 2015. PMID: 25897704
84 results