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Page 1
Adipose stem cells are sexually dimorphic cells with dual roles as preadipocytes and resident fibroblasts.
Uhrbom M, Muhl L, Genové G, Liu J, Palmgren H, Alexandersson I, Karlsson F, Zhou AX, Lunnerdal S, Gustafsson S, Buyandelger B, Petkevicius K, Ahlstedt I, Karlsson D, Aasehaug L, He L, Jeansson M, Betsholtz C, Peng XR. Uhrbom M, et al. Among authors: ahlstedt i. Nat Commun. 2024 Sep 2;15(1):7643. doi: 10.1038/s41467-024-51867-9. Nat Commun. 2024. PMID: 39223126 Free PMC article.
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis.
Liu C, Schönke M, Spoorenberg B, Lambooij JM, van der Zande HJP, Zhou E, Tushuizen ME, Andreasson AC, Park A, Oldham S, Uhrbom M, Ahlstedt I, Ikeda Y, Wallenius K, Peng XR, Guigas B, Boon MR, Wang Y, Rensen PCN. Liu C, et al. Among authors: ahlstedt i. Elife. 2023 Jan 17;12:e83075. doi: 10.7554/eLife.83075. Elife. 2023. PMID: 36648330 Free PMC article.
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis.
Petkevicius K, Palmgren H, Glover MS, Ahnmark A, Andréasson AC, Madeyski-Bengtson K, Kawana H, Allman EL, Kaper D, Uhrbom M, Andersson L, Aasehaug L, Forsström J, Wallin S, Ahlstedt I, Leke R, Karlsson D, González-King H, Löfgren L, Nilsson R, Pellegrini G, Kono N, Aoki J, Hess S, Sienski G, Pilon M, Bohlooly-Y M, Maresca M, Peng XR. Petkevicius K, et al. Among authors: ahlstedt i. Nat Commun. 2022 Oct 14;13(1):6020. doi: 10.1038/s41467-022-33735-6. Nat Commun. 2022. PMID: 36241646 Free PMC article.
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.
Lindén D, Ahnmark A, Pingitore P, Ciociola E, Ahlstedt I, Andréasson AC, Sasidharan K, Madeyski-Bengtson K, Zurek M, Mancina RM, Lindblom A, Bjursell M, Böttcher G, Ståhlman M, Bohlooly-Y M, Haynes WG, Carlsson B, Graham M, Lee R, Murray S, Valenti L, Bhanot S, Åkerblad P, Romeo S. Lindén D, et al. Among authors: ahlstedt i. Mol Metab. 2019 Apr;22:49-61. doi: 10.1016/j.molmet.2019.01.013. Epub 2019 Feb 5. Mol Metab. 2019. PMID: 30772256 Free PMC article.
Targeted delivery of antisense oligonucleotides to pancreatic β-cells.
Ämmälä C, Drury WJ 3rd, Knerr L, Ahlstedt I, Stillemark-Billton P, Wennberg-Huldt C, Andersson EM, Valeur E, Jansson-Löfmark R, Janzén D, Sundström L, Meuller J, Claesson J, Andersson P, Johansson C, Lee RG, Prakash TP, Seth PP, Monia BP, Andersson S. Ämmälä C, et al. Among authors: ahlstedt i. Sci Adv. 2018 Oct 17;4(10):eaat3386. doi: 10.1126/sciadv.aat3386. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30345352 Free PMC article.
Modeling human pancreatic beta cell dedifferentiation.
Diedisheim M, Oshima M, Albagli O, Huldt CW, Ahlstedt I, Clausen M, Menon S, Aivazidis A, Andreasson AC, Haynes WG, Marchetti P, Marselli L, Armanet M, Chimienti F, Scharfmann R. Diedisheim M, et al. Among authors: ahlstedt i. Mol Metab. 2018 Apr;10:74-86. doi: 10.1016/j.molmet.2018.02.002. Epub 2018 Feb 8. Mol Metab. 2018. PMID: 29472102 Free PMC article.
Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms.
Lelliott CJ, Ahnmark A, Admyre T, Ahlstedt I, Irving L, Keyes F, Patterson L, Mumphrey MB, Bjursell M, Gorman T, Bohlooly-Y M, Buchanan A, Harrison P, Vaughan T, Berthoud HR, Lindén D. Lelliott CJ, et al. Among authors: ahlstedt i. PLoS One. 2014 Nov 26;9(11):e112109. doi: 10.1371/journal.pone.0112109. eCollection 2014. PLoS One. 2014. PMID: 25427253 Free PMC article.
19 results