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Mitochondrial chaperon TNF-receptor- associated protein 1 as a novel apoptotic regulator conferring susceptibility to Pneumocystis jirovecii pneumonia.
Amali AA, Paramasivam K, Huang CH, Joshi A, Hirpara JL, Ravikumar S, Sam QH, Tan RYM, Tan Z, Kumar D, Neckers LM, Pervaiz S, Foo R, Chan CYY, Zhu J, Lee C, Chai LYA. Amali AA, et al. Among authors: neckers lm. Front Immunol. 2024 Aug 19;15:1423086. doi: 10.3389/fimmu.2024.1423086. eCollection 2024. Front Immunol. 2024. PMID: 39224595 Free PMC article.
An update on the status of HSP90 inhibitors in cancer clinical trials.
Rastogi S, Joshi A, Sato N, Lee S, Lee MJ, Trepel JB, Neckers L. Rastogi S, et al. Cell Stress Chaperones. 2024 Aug;29(4):519-539. doi: 10.1016/j.cstres.2024.05.005. Epub 2024 Jun 13. Cell Stress Chaperones. 2024. PMID: 38878853 Free PMC article. Review.
Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8-9, 2022.
van Oosten-Hawle P, Backe SJ, Ben-Zvi A, Bourboulia D, Brancaccio M, Brodsky J, Clark M, Colombo G, Cox MB, De Los Rios P, Echtenkamp F, Edkins A, Freeman B, Goloubinoff P, Houry W, Johnson J, LaPointe P, Li W, Mezger V, Neckers L, Nillegoda NB, Prahlad V, Reitzel A, Scherz-Shouval R, Sistonen L, Tsai FTF, Woodford MR, Mollapour M, Truman AW. van Oosten-Hawle P, et al. Cell Stress Chaperones. 2023 Jan;28(1):1-9. doi: 10.1007/s12192-022-01318-5. Epub 2023 Jan 5. Cell Stress Chaperones. 2023. PMID: 36602710 Free PMC article.
Dual inhibition of oxidative phosphorylation and glycolysis exerts a synergistic antitumor effect on colorectal and gastric cancer by creating energy depletion and preventing metabolic switch.
Aisu Y, Oshima N, Hyodo F, Elhelaly AE, Masuo A, Okada T, Hisamori S, Tsunoda S, Hida K, Morimoto T, Miyoshi H, Taketo MM, Matsuo M, Neckers LM, Sakai Y, Obama K. Aisu Y, et al. Among authors: neckers lm. PLoS One. 2024 Dec 12;19(12):e0309700. doi: 10.1371/journal.pone.0309700. eCollection 2024. PLoS One. 2024. PMID: 39666615 Free PMC article.
Genome-Wide Analysis Identifies Nuclear Factor 1C as a Novel Transcription Factor and Potential Therapeutic Target in SCLC.
Shukla V, Wang H, Varticovski L, Baek S, Wang R, Wu X, Echtenkamp F, Villa-Hernandez F, Prothro KP, Gara SK, Zhang MR, Shiffka S, Raziuddin R, Neckers LM, Linehan WM, Chen H, Hager GL, Schrump DS. Shukla V, et al. Among authors: neckers lm. J Thorac Oncol. 2024 Aug;19(8):1201-1217. doi: 10.1016/j.jtho.2024.03.023. Epub 2024 Apr 5. J Thorac Oncol. 2024. PMID: 38583771
Second international symposium on the chaperone code, 2023.
Buchner J, Alasady MJ, Backe SJ, Blagg BSJ, Carpenter RL, Colombo G, Gelis I, Gewirth DT, Gierasch LM, Houry WA, Johnson JL, Kang BH, Kao AW, LaPointe P, Mattoo S, McClellan AJ, Neckers LM, Prodromou C, Rasola A, Sager RA, Theodoraki MA, Truman AW, Truttman MC, Zachara NE, Bourboulia D, Mollapour M, Woodford MR. Buchner J, et al. Among authors: neckers lm. Cell Stress Chaperones. 2024 Feb;29(1):88-96. doi: 10.1016/j.cstres.2024.01.003. Epub 2024 Feb 3. Cell Stress Chaperones. 2024. PMID: 38316354 Free PMC article. No abstract available.
Inhibition of NAD+-Dependent Metabolic Processes Induces Cellular Necrosis and Tumor Regression in Rhabdomyosarcoma Models.
McKay-Corkum GB, Collins VJ, Yeung C, Ito T, Issaq SH, Holland D, Vulikh K, Zhang Y, Lee U, Lei H, Mendoza A, Shern JF, Yohe ME, Yamamoto K, Wilson K, Ji J, Karim BO, Thomas CJ, Krishna MC, Neckers LM, Heske CM. McKay-Corkum GB, et al. Among authors: neckers lm. Clin Cancer Res. 2023 Nov 1;29(21):4479-4491. doi: 10.1158/1078-0432.CCR-23-0200. Clin Cancer Res. 2023. PMID: 37616468 Free PMC article.
164 results