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433 results

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Page 1
Single-cell analysis of breast cancer metastasis reveals epithelial-mesenchymal plasticity signatures associated with poor outcomes.
Winkler J, Tan W, Diadhiou CM, McGinnis CS, Abbasi A, Hasnain S, Durney S, Atamaniuc E, Superville D, Awni L, Lee JV, Hinrichs JH, Wagner PS, Singh N, Hein MY, Borja M, Detweiler AM, Liu SY, Nanjaraj A, Sitarama V, Rugo HS, Neff N, Gartner ZJ, Oliveira Pisco A, Goga A, Darmanis S, Werb Z. Winkler J, et al. Among authors: neff n. J Clin Invest. 2024 Sep 3;134(17):e164227. doi: 10.1172/JCI164227. J Clin Invest. 2024. PMID: 39225101 Free PMC article.
A 2-Gene Host Signature for Improved Accuracy of COVID-19 Diagnosis Agnostic to Viral Variants.
Albright J, Mick E, Sanchez-Guerrero E, Kamm J, Mitchell A, Detweiler AM, Neff N, Tsitsiklis A, Hayakawa Serpa P, Ratnasiri K, Havlir D, Kistler A, DeRisi JL, Pisco AO, Langelier CR. Albright J, et al. Among authors: neff n. mSystems. 2023 Feb 23;8(1):e0067122. doi: 10.1128/msystems.00671-22. Epub 2022 Dec 12. mSystems. 2023. PMID: 36507688 Free PMC article.
Integrated host/microbe metagenomics enables accurate lower respiratory tract infection diagnosis in critically ill children.
Mick E, Tsitsiklis A, Kamm J, Kalantar KL, Caldera S, Lyden A, Tan M, Detweiler AM, Neff N, Osborne CM, Williamson KM, Soesanto V, Leroue M, Maddux AB, Simões EA, Carpenter TC, Wagner BD, DeRisi JL, Ambroggio L, Mourani PM, Langelier CR. Mick E, et al. Among authors: neff n. J Clin Invest. 2023 Apr 3;133(7):e165904. doi: 10.1172/JCI165904. J Clin Invest. 2023. PMID: 37009900 Free PMC article.
In host evolution of beta lactam resistance during active treatment for Pseudomonas aeruginosa bacteremia.
Spottiswoode N, Hao S, Sanchez-Guerrero E, Detweiler AM, Mekonen H, Neff N, Macmillan H, Schwartz BS, Engel J, DeRisi JL, Miller SA, Langelier CR. Spottiswoode N, et al. Among authors: neff n. Front Cell Infect Microbiol. 2023 Aug 30;13:1241608. doi: 10.3389/fcimb.2023.1241608. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37712060 Free PMC article.
A multimodal zebrafish developmental atlas reveals the state-transition dynamics of late-vertebrate pluripotent axial progenitors.
Lange M, Granados A, VijayKumar S, Bragantini J, Ancheta S, Kim YJ, Santhosh S, Borja M, Kobayashi H, McGeever E, Solak AC, Yang B, Zhao X, Liu Y, Detweiler AM, Paul S, Theodoro I, Mekonen H, Charlton C, Lao T, Banks R, Xiao S, Jacobo A, Balla K, Awayan K, D'Souza S, Haase R, Dizeux A, Pourquie O, Gómez-Sjöberg R, Huber G, Serra M, Neff N, Pisco AO, Royer LA. Lange M, et al. Among authors: neff n. Cell. 2024 Nov 14;187(23):6742-6759.e17. doi: 10.1016/j.cell.2024.09.047. Epub 2024 Oct 24. Cell. 2024. PMID: 39454574 Free article.
Impaired immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19.
Tsitsiklis A, Zha BS, Byrne A, Devoe C, Levan S, Rackaityte E, Sunshine S, Mick E, Ghale R, Jauregui A, Sarma A, Neff N, Serpa PH, Deiss TJ, Kistler A, Carrillo S, Ansel KM, Leligdowicz A, Christenson S, Jones N, Wu B, Darmanis S, Matthay MA, Lynch SV, DeRisi JL; COMET Consortium; Hendrickson CM, Kangelaris KN, Krummel MF, Woodruff PG, Erle DJ, Rosenberg O, Calfee CS, Langelier CR. Tsitsiklis A, et al. Among authors: neff n. Res Sq [Preprint]. 2021 Apr 23:rs.3.rs-380803. doi: 10.21203/rs.3.rs-380803/v1. Res Sq. 2021. PMID: 34013247 Free PMC article. Preprint.
A myeloid program associated with COVID-19 severity is decreased by therapeutic blockade of IL-6 signaling.
Hackney JA, Shivram H, Vander Heiden J, Overall C, Orozco L, Gao X, Kim E, West N, Qamra A, Chang D, Chakrabarti A, Choy DF, Combes AJ, Courau T, Fragiadakis GK, Rao AA, Ray A, Tsui J, Hu K, Kuhn NF, Krummel MF, Erle DJ, Kangelaris K, Sarma A, Lyon Z, Calfee CS, Woodruff PG, Ghale R, Mick E, Byrne A, Zha BS, Langelier C, Hendrickson CM, van der Wijst MGP, Hartoularos GC, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Ye CJ; UCSF COMET Consortium; Ramalingam T, McBride JM, Cai F, Teterina A, Bao M, Tsai L, Rosas IO, Regev A, Kapadia SB, Bauer RN, Rosenberger CM. Hackney JA, et al. iScience. 2023 Sep 1;26(10):107813. doi: 10.1016/j.isci.2023.107813. eCollection 2023 Oct 20. iScience. 2023. PMID: 37810211 Free PMC article.
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiency.
Pavel-Dinu M, Gardner CL, Nakauchi Y, Kawai T, Delmonte OM, Palterer B, Bosticardo M, Pala F, Viel S, Malech HL, Ghanim HY, Bode NM, Kurgan GL, Detweiler AM, Vakulskas CA, Neff NF, Sheikali A, Menezes ST, Chrobok J, Hernández González EM, Majeti R, Notarangelo LD, Porteus MH. Pavel-Dinu M, et al. Blood Adv. 2024 Apr 9;8(7):1820-1833. doi: 10.1182/bloodadvances.2023011766. Blood Adv. 2024. PMID: 38096800 Free PMC article.
433 results