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Page 1
Benchmarking Alzheimer's disease prediction: personalised risk assessment using polygenic risk scores across various methodologies and genome-wide studies.
Bellou E, Kim W, Leonenko G, Tao F, Simmonds E, Wu Y, Mattsson-Carlgren N, Hansson O, Nagle MW, Escott-Price V; Alzheimer’s Disease Neuroimaging Initiative. Bellou E, et al. Among authors: leonenko g. Alzheimers Res Ther. 2025 Jan 6;17(1):6. doi: 10.1186/s13195-024-01664-9. Alzheimers Res Ther. 2025. PMID: 39762974 Free PMC article.
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia.
Manzoni C, Kia DA, Ferrari R, Leonenko G, Costa B, Saba V, Jabbari E, Tan MM, Albani D, Alvarez V, Alvarez I, Andreassen OA, Angiolillo A, Arighi A, Baker M, Benussi L, Bessi V, Binetti G, Blackburn DJ, Boada M, Boeve BF, Borrego-Ecija S, Borroni B, Bråthen G, Brooks WS, Bruni AC, Caroppo P, Bandres-Ciga S, Clarimon J, Colao R, Cruchaga C, Danek A, de Boer SC, de Rojas I, di Costanzo A, Dickson DW, Diehl-Schmid J, Dobson-Stone C, Dols-Icardo O, Donizetti A, Dopper E, Durante E, Ferrari C, Forloni G, Frangipane F, Fratiglioni L, Kramberger MG, Galimberti D, Gallucci M, García-González P, Ghidoni R, Giaccone G, Graff C, Graff-Radford NR, Grafman J, Halliday GM, Hernandez DG, Hjermind LE, Hodges JR, Holloway G, Huey ED, Illán-Gala I, Josephs KA, Knopman DS, Kristiansen M, Kwok JB, Leber I, Leonard HL, Libri I, Lleo A, Mackenzie IR, Madhan GK, Maletta R, Marquié M, Maver A, Menendez-Gonzalez M, Milan G, Miller BL, Morris CM, Morris HR, Nacmias B, Newton J, Nielsen JE, Nilsson C, Novelli V, Padovani A, Pal S, Pasquier F, Pastor P, Perneczky R, Peterlin B, Petersen RC, Piguet O, Pijnenburg YA, Puca AA, Rademakers R, Rainero I, Reus LM, Richardson AM, Riemenschneider M, Rogaeva E,… See abstract for full author list ➔ Manzoni C, et al. Among authors: leonenko g. Am J Hum Genet. 2024 Jul 11;111(7):1316-1329. doi: 10.1016/j.ajhg.2024.05.017. Epub 2024 Jun 17. Am J Hum Genet. 2024. PMID: 38889728 Free PMC article.
Dementias Platform UK: Bringing genetics into life.
Leonenko G, Bauermeister S, Ghanti D, Stevenson-Hoare J, Simmonds E, Brookes K, Morgan K, Chaturvedi N, Elliott P, Thomas A, Wareham N, Gallacher J, Escott-Price V. Leonenko G, et al. Alzheimers Dement. 2024 May;20(5):3281-3289. doi: 10.1002/alz.13782. Epub 2024 Mar 20. Alzheimers Dement. 2024. PMID: 38506636 Free PMC article.
What does heritability of Alzheimer's disease represent?
Baker E, Leonenko G, Schmidt KM, Hill M, Myers AJ, Shoai M, de Rojas I, Tesi N, Holstege H, van der Flier WM, Pijnenburg YAL, Ruiz A, Hardy J, van der Lee S, Escott-Price V. Baker E, et al. Among authors: leonenko g. PLoS One. 2023 Apr 28;18(4):e0281440. doi: 10.1371/journal.pone.0281440. eCollection 2023. PLoS One. 2023. PMID: 37115753 Free PMC article.
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, Sims R, Bellenguez C, Quintela I, González-Perez A, Calero M, Franco-Macías E, Macías J, Blesa R, Cervera-Carles L, Menéndez-González M, Frank-García A, Royo JL, Moreno F, Huerto Vilas R, Baquero M, Diez-Fairen M, Lage C, García-Madrona S, García-González P, Alarcón-Martín E, Valero S, Sotolongo-Grau O, Ullgren A, Naj AC, Lemstra AW, Benaque A, Pérez-Cordón A, Benussi A, Rábano A, Padovani A, Squassina A, de Mendonça A, Arias Pastor A, Kok AAL, Meggy A, Pastor AB, Espinosa A, Corma-Gómez A, Martín Montes A, Sanabria Á, DeStefano AL, Schneider A, Haapasalo A, Kinhult Ståhlbom A, Tybjærg-Hansen A, Hartmann AM, Spottke A, Corbatón-Anchuelo A, Rongve A, Borroni B, Arosio B, Nacmias B, Nordestgaard BG, Kunkle BW, Charbonnier C, Abdelnour C, Masullo C, Martínez Rodríguez C, Muñoz-Fernandez C, Dufouil C, Graff C, Ferreira CB, Chillotti C, Reynolds CA, Fenoglio C, Van Broeckhoven C, Clark C, Pisanu C, Satizabal CL, Holmes C, Buiza-Rueda D, Aarsland D, Rujescu D, Alcolea D, Galimberti D, Wallon D, Seripa D, Grün… See abstract for full author list ➔ de Rojas I, et al. Nat Commun. 2023 Feb 9;14(1):716. doi: 10.1038/s41467-023-36192-x. Nat Commun. 2023. PMID: 36759603 Free PMC article. No abstract available.
Golgi apparatus, endoplasmic reticulum and mitochondrial function implicated in Alzheimer's disease through polygenic risk and RNA sequencing.
Crawford K, Leonenko G, Baker E, Grozeva D, Lan-Leung B, Holmans P, Williams J, O'Donovan MC, Escott-Price V, Ivanov DK. Crawford K, et al. Among authors: leonenko g. Mol Psychiatry. 2023 Mar;28(3):1327-1336. doi: 10.1038/s41380-022-01926-8. Epub 2022 Dec 28. Mol Psychiatry. 2023. PMID: 36577842 Free PMC article.
Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study.
Wagen AZ, Coath W, Keshavan A, James SN, Parker TD, Lane CA, Buchanan SM, Keuss SE, Storey M, Lu K, Macdougall A, Murray-Smith H, Freiberger T, Cash DM, Malone IB, Barnes J, Sudre CH, Wong A, Pavisic IM, Street R, Crutch SJ, Escott-Price V, Leonenko G, Zetterberg H, Wellington H, Heslegrave A, Barkhof F, Richards M, Fox NC, Cole JH, Schott JM. Wagen AZ, et al. Among authors: leonenko g. Lancet Healthy Longev. 2022 Sep;3(9):e607-e616. doi: 10.1016/S2666-7568(22)00167-2. Epub 2022 Aug 22. Lancet Healthy Longev. 2022. PMID: 36102775 Free PMC article.
34 results