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Page 1
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.
Sun C, Seranova E, Cohen MA, Chipara M, Roberts J, Astuti D, Palhegyi AM, Acharjee A, Sedlackova L, Kataura T, Otten EG, Panda PK, Lara-Reyna S, Korsgen ME, Kauffman KJ, Huerta-Uribe A, Zatyka M, Silva LFSE, Torresi J, Zhang S, Hughes GW, Ward C, Kuechler ER, Cartwright D, Trushin S, Trushina E, Sahay G, Buganim Y, Lavery GG, Gsponer J, Anderson DG, Frickel EM, Rosenstock TR, Barrett T, Maddocks ODK, Tennant DA, Wang H, Jaenisch R, Korolchuk VI, Sarkar S. Sun C, et al. Among authors: jaenisch r. Cell Rep. 2023 May 30;42(5):112372. doi: 10.1016/j.celrep.2023.112372. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37086404 Free PMC article.
Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2.
Flamier A, Bisht P, Richards A, Tomasello DL, Jaenisch R. Flamier A, et al. Among authors: jaenisch r. iScience. 2023 Aug 19;26(9):107690. doi: 10.1016/j.isci.2023.107690. eCollection 2023 Sep 15. iScience. 2023. PMID: 37680484 Free PMC article.
Abortive infection of bat fibroblasts with SARS-CoV-2.
Bisht P, Gallagher MD, Barrasa MI, Boucau J, Harding A, Déjosez M, Godoy-Parejo C, Bisher ME, de Nola G, Lytton-Jean AKR, Gehrke L, Zwaka TP, Jaenisch R. Bisht P, et al. Among authors: jaenisch r. Proc Natl Acad Sci U S A. 2024 Oct 22;121(43):e2406773121. doi: 10.1073/pnas.2406773121. Epub 2024 Oct 14. Proc Natl Acad Sci U S A. 2024. PMID: 39401365 Free PMC article.
Tunable Conductive Hydrogel Scaffolds for Neural Cell Differentiation.
Tringides CM, Boulingre M, Khalil A, Lungjangwa T, Jaenisch R, Mooney DJ. Tringides CM, et al. Among authors: jaenisch r. Adv Healthc Mater. 2023 Mar;12(7):e2202221. doi: 10.1002/adhm.202202221. Epub 2022 Dec 23. Adv Healthc Mater. 2023. PMID: 36495560 Free PMC article.
Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions.
Lam I, Ndayisaba A, Lewis AJ, Fu Y, Sagredo GT, Kuzkina A, Zaccagnini L, Celikag M, Sandoe J, Sanz RL, Vahdatshoar A, Martin TD, Morshed N, Ichihashi T, Tripathi A, Ramalingam N, Oettgen-Suazo C, Bartels T, Boussouf M, Schäbinger M, Hallacli E, Jiang X, Verma A, Tea C, Wang Z, Hakozaki H, Yu X, Hyles K, Park C, Wang X, Theunissen TW, Wang H, Jaenisch R, Lindquist S, Stevens B, Stefanova N, Wenning G, van de Berg WDJ, Luk KC, Sanchez-Pernaute R, Gómez-Esteban JC, Felsky D, Kiyota Y, Sahni N, Yi SS, Chung CY, Stahlberg H, Ferrer I, Schöneberg J, Elledge SJ, Dettmer U, Halliday GM, Bartels T, Khurana V. Lam I, et al. Among authors: jaenisch r. Neuron. 2024 Sep 4;112(17):2886-2909.e16. doi: 10.1016/j.neuron.2024.06.002. Epub 2024 Jul 29. Neuron. 2024. PMID: 39079530 Free PMC article.
Autophagy promotes cell survival by maintaining NAD levels.
Kataura T, Sedlackova L, Otten EG, Kumari R, Shapira D, Scialo F, Stefanatos R, Ishikawa KI, Kelly G, Seranova E, Sun C, Maetzel D, Kenneth N, Trushin S, Zhang T, Trushina E, Bascom CC, Tasseff R, Isfort RJ, Oblong JE, Miwa S, Lazarou M, Jaenisch R, Imoto M, Saiki S, Papamichos-Chronakis M, Manjithaya R, Maddocks ODK, Sanz A, Sarkar S, Korolchuk VI. Kataura T, et al. Among authors: jaenisch r. Dev Cell. 2022 Nov 21;57(22):2584-2598.e11. doi: 10.1016/j.devcel.2022.10.008. Dev Cell. 2022. PMID: 36413951 Free PMC article.
651 results