Bhagwat B - Search Results

1

Discovery and Evaluation of TLR-Targeted Immune Agonists.

Chernyak N, Bhagwat B, Naravula S, Chen Y, Solban N, Zhang F, Kofman E, Raoufi F, Dang X, Bao J, Tomazela D, Baily M, Geierstanger B, Flygare JA, Han JH, Willingham A, Seganish WM. Chernyak N, et al. Among authors: bhagwat b. J Med Chem. 2024 Sep 26;67(18):16222-16234. doi: 10.1021/acs.jmedchem.4c00804. Epub 2024 Sep 5. J Med Chem. 2024. PMID: 39235949

2

Design and Optimization of Selectivity-Tunable Toll-like Receptor 7/8 Agonists as Novel Antibody-Drug Conjugate Payloads.

Patel AM, Willingham A, Cheng AC, Tomazela D, Bowman E, Kofman E, Zhang F, Bao J, Sanzone JR, Choy JW, Flygare JA, Han JH, Pradhan K, Kieffer M, Chernyak N, Akbari P, Liu P, Mehmood R, Naravula S, Hollingsworth SA, Bhagwat B, Lang SB, Seganish WM. Patel AM, et al. Among authors: bhagwat b. J Med Chem. 2024 Sep 12;67(17):15756-15779. doi: 10.1021/acs.jmedchem.4c01384. Epub 2024 Aug 22. J Med Chem. 2024. PMID: 39172064

3

Development and application of an in vitro assay to assess target-independent B-cell activation by targeted TLR7 immune agonists.

Chen Y, Zhou S, Pradhan K, Chernyak N, Kofman E, Zhang F, Kim SY, Seghezzi W, Willingham A, Seganish WM, Bhagwat B, Han JH. Chen Y, et al. Among authors: bhagwat b. J Immunol Methods. 2023 Nov;522:113553. doi: 10.1016/j.jim.2023.113553. Epub 2023 Sep 1. J Immunol Methods. 2023. PMID: 37661047 Free article.

4

Investigating combination benefit of PD1 and LAG3 co-blockade using an engineered cellular bioassay.

Bhagwat B, de Waal Malefyt R, Willingham A. Bhagwat B, et al. Int Immunopharmacol. 2023 Jun;119:109566. doi: 10.1016/j.intimp.2022.109566. Epub 2023 Apr 10. Int Immunopharmacol. 2023. PMID: 37044037 Free article.

5

Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells.

Sukumar S, Wilson DC, Yu Y, Wong J, Naravula S, Ermakov G, Riener R, Bhagwat B, Necheva AS, Grein J, Churakova T, Mangadu R, Georgiev P, Manfra D, Pinheiro EM, Sriram V, Bailey WJ, Herzyk D, McClanahan TK, Willingham A, Beebe AM, Sadekova S. Sukumar S, et al. Among authors: bhagwat b. Cancer Res. 2017 Aug 15;77(16):4378-4388. doi: 10.1158/0008-5472.CAN-16-1439. Epub 2017 Jun 13. Cancer Res. 2017. PMID: 28611044

6

Evaluation of a TGN1412 analogue using in vitro assays and two immune humanized mouse models.

Yan H, Bhagwat B, Sanden D, Willingham A, Tan A, Knapton AD, Weaver JL, Howard KE. Yan H, et al. Among authors: bhagwat b. Toxicol Appl Pharmacol. 2019 Jun 1;372:57-69. doi: 10.1016/j.taap.2019.03.020. Epub 2019 Mar 23. Toxicol Appl Pharmacol. 2019. PMID: 30914376

7

Establishment of engineered cell-based assays mediating LAG3 and PD1 immune suppression enables potency measurement of blocking antibodies and assessment of signal transduction.

Bhagwat B, Cherwinski H, Sathe M, Seghezzi W, McClanahan TK, de Waal Malefyt R, Willingham A. Bhagwat B, et al. J Immunol Methods. 2018 May;456:7-14. doi: 10.1016/j.jim.2018.02.003. Epub 2018 Feb 8. J Immunol Methods. 2018. PMID: 29427592 Free article.

8

Genetic diversity of strawberry mild yellow edge virus from eastern Canada.

Xiang Y, Nie X, Bernardy M, Liu JJ, Su L, Bhagwat B, Dickison V, Holmes J, Grose JM, Creelman AC. Xiang Y, et al. Among authors: bhagwat b. Arch Virol. 2020 Apr;165(4):923-935. doi: 10.1007/s00705-020-04561-2. Epub 2020 Mar 3. Arch Virol. 2020. PMID: 32128611

9

Association of Practices Regarding Infant and Young Child Feeding with Anthropometry Measurements Among an Urban Population in Karnataka, India.

Bhagwat B, Chandrashekar Nooyi S, Krishnareddy DH, Murthy SN. Bhagwat B, et al. Cureus. 2019 Mar 29;11(3):e4346. doi: 10.7759/cureus.4346. Cureus. 2019. PMID: 31187011 Free PMC article.

10

Application of Next Generation Sequencing for Diagnostic Testing of Tree Fruit Viruses and Viroids.

Rott M, Xiang Y, Boyes I, Belton M, Saeed H, Kesanakurti P, Hayes S, Lawrence T, Birch C, Bhagwat B, Rast H. Rott M, et al. Among authors: bhagwat b. Plant Dis. 2017 Aug;101(8):1489-1499. doi: 10.1094/PDIS-03-17-0306-RE. Epub 2017 Jun 26. Plant Dis. 2017. PMID: 30678581

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