Micalizio GC - Search Results

1

Merging Natural Product Structures with Pharmaceutical Leads: Unnatural Enantiomers of Estranes as Glucocorticoid Receptor Modulators That Suppress TNF-α and IL-6 Release.

Nicholson JM, Yang D, Koelblen T, Hu EL, Coss CC, Burris TP, Hu X, Micalizio GC. Nicholson JM, et al. Among authors: micalizio gc. J Med Chem. 2024 Sep 26;67(18):16185-16194. doi: 10.1021/acs.jmedchem.4c01007. Epub 2024 Sep 6. J Med Chem. 2024. PMID: 39240657

2

Asymmetric Total Syntheses of Euphol and Tirucallol.

Nicholson JM, Micalizio GC. Nicholson JM, et al. Among authors: micalizio gc. Org Lett. 2023 Aug 4;25(30):5687-5691. doi: 10.1021/acs.orglett.3c02187. Epub 2023 Jul 21. Org Lett. 2023. PMID: 37477981 Free PMC article.

3

From Functional Fatty Acids to Potent and Selective Natural-Product-Inspired Mimetics via Conformational Profiling.

Markham LE, Koelblen T, Chobanian HR, Follis AV, Burris TP, Micalizio GC. Markham LE, et al. Among authors: micalizio gc. ACS Cent Sci. 2024 Feb 12;10(2):477-486. doi: 10.1021/acscentsci.3c01155. eCollection 2024 Feb 28. ACS Cent Sci. 2024. PMID: 38435518 Free PMC article.

4

Function-Oriented Synthesis of Pentacyclic Triterpenoids and Discovery of an ent-Estrane as a Natural Product-Inspired Androgen Receptor Antagonist.

Stempel ZD, Radomska HS, Coss CC, Micalizio GC. Stempel ZD, et al. Among authors: micalizio gc. Org Lett. 2024 Apr 19;26(15):3054-3059. doi: 10.1021/acs.orglett.4c00697. Epub 2024 Apr 1. Org Lett. 2024. PMID: 38557107

5

Synthesis of alkaloid (-)-205B via stereoselective reductive cross-coupling and intramolecular [3+2] cycloaddition.

Yang D, Micalizio GC. Yang D, et al. Among authors: micalizio gc. J Am Chem Soc. 2012 Sep 19;134(37):15237-40. doi: 10.1021/ja306362m. Epub 2012 Sep 7. J Am Chem Soc. 2012. PMID: 22957796 Free PMC article.

6

General Enantioselective and Stereochemically Divergent Four-Stage Approach to Fused Tetracyclic Terpenoid Systems.

Nicholson JM, Millham AB, Bucknam AR, Markham LE, Sailors XI, Micalizio GC. Nicholson JM, et al. Among authors: micalizio gc. J Org Chem. 2022 Mar 4;87(5):3352-3362. doi: 10.1021/acs.joc.1c02979. Epub 2022 Feb 17. J Org Chem. 2022. PMID: 35175755 Free PMC article.

7

Progress toward the De Novo Asymmetric Synthesis of Euphanes.

Wai H, Koelblen T, Hayes ME, Burris TP, Micalizio GC. Wai H, et al. Among authors: micalizio gc. Org Lett. 2022 May 27;24(20):3686-3690. doi: 10.1021/acs.orglett.2c01299. Epub 2022 May 18. Org Lett. 2022. PMID: 35584298 Free PMC article.

8

A convergent stereoselective synthesis of quinolizidines and indolizidines: chemoselective coupling of 2-hydroxymethyl-substituted allylic silanes with imines.

Yang D, Micalizio GC. Yang D, et al. Among authors: micalizio gc. J Am Chem Soc. 2009 Dec 9;131(48):17548-9. doi: 10.1021/ja908504z. J Am Chem Soc. 2009. PMID: 19950989 Free PMC article.

9

Convergent and stereodivergent synthesis of complex 1-aza-7-oxabicyclo[2.2.1]heptanes.

Yang D, Micalizio GC. Yang D, et al. Among authors: micalizio gc. J Am Chem Soc. 2011 Jun 22;133(24):9216-9. doi: 10.1021/ja202900h. Epub 2011 May 23. J Am Chem Soc. 2011. PMID: 21604673 Free PMC article.

10

A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ.

Kim WS, Shalit ZA, Nguyen SM, Schoepke E, Eastman A, Burris TP, Gaur AB, Micalizio GC. Kim WS, et al. Among authors: micalizio gc. Nat Commun. 2019 Jun 4;10(1):2448. doi: 10.1038/s41467-019-10415-6. Nat Commun. 2019. PMID: 31164645 Free PMC article.

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