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ThymoSpheres culture: A model to study human polyclonal unconventional T cells.
Billiet L, Jansen H, Pille M, Boehme L, Sanchez Sanchez G, De Cock L, Goetgeluk G, Pascal E, De Munter S, Deseins L, Ingels J, Michiels T, De Vos R, Zolfaghari A, Vandamme N, Roels J, Kerre T, Dmitriev RI, Taghon T, Vermijlen D, Vandekerckhove B. Billiet L, et al. Eur J Immunol. 2024 Dec;54(12):e2451265. doi: 10.1002/eji.202451265. Epub 2024 Sep 9. Eur J Immunol. 2024. PMID: 39246170 Free PMC article.
Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage.
Billiet L, De Cock L, Sanchez Sanchez G, Mayer RL, Goetgeluk G, De Munter S, Pille M, Ingels J, Jansen H, Weening K, Pascal E, Raes K, Bonte S, Kerre T, Vandamme N, Seurinck R, Roels J, Lavaert M, Van Nieuwerburgh F, Leclercq G, Taghon T, Impens F, Menten B, Vermijlen D, Vandekerckhove B. Billiet L, et al. J Exp Med. 2023 Jun 5;220(6):e20220942. doi: 10.1084/jem.20220942. Epub 2023 Mar 20. J Exp Med. 2023. PMID: 36939517 Free PMC article.
Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a- CD95+ CD28- CCR7- Developmental Stage.
Billiet L, Goetgeluk G, Bonte S, De Munter S, De Cock L, Pille M, Ingels J, Jansen H, Weening K, Van Nieuwerburgh F, Kerre T, Taghon T, Leclercq G, Vandekerckhove B. Billiet L, et al. Int J Mol Sci. 2020 Nov 20;21(22):8785. doi: 10.3390/ijms21228785. Int J Mol Sci. 2020. PMID: 33233766 Free PMC article.
In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality.
Bonte S, de Munter S, Billiet L, Goetgeluk G, Ingels J, Jansen H, Pille M, de Cock L, Weening K, Taghon T, Leclercq G, Vandekerckhove B, Kerre T. Bonte S, et al. Among authors: billiet l. Oncoimmunology. 2021 Jul 25;10(1):1954800. doi: 10.1080/2162402X.2021.1954800. eCollection 2021. Oncoimmunology. 2021. PMID: 34367734 Free PMC article.
The Wiskott-Aldrich syndrome protein is required for positive selection during T-cell lineage differentiation.
Pille M, Avila J, Sanchez GS, Goetgeluk G, De Munter S, Jansen H, Billiet L, Weening K, Xue H, Bonte S, Ingels J, De Cock L, Pascal E, Deseins L, Kerre T, Taghon T, Leclercq G, Vermijlen D, Davis B, Vandekerckhove B. Pille M, et al. Among authors: billiet l. Front Immunol. 2023 Jun 7;14:1188099. doi: 10.3389/fimmu.2023.1188099. eCollection 2023. Front Immunol. 2023. PMID: 37350958 Free PMC article.
Knocking Out CD70 Rescues CD70-Specific NanoCAR T Cells from Antigen-Induced Exhaustion.
De Munter S, Buhl JL, De Cock L, Van Parys A, Daneels W, Pascal E, Deseins L, Ingels J, Goetgeluk G, Jansen H, Billiet L, Pille M, Van Duyse J, Bonte S, Vandamme N, Van Dorpe J, Offner F, Leclercq G, Taghon T, Depla E, Tavernier J, Kerre T, Drost J, Vandekerckhove B. De Munter S, et al. Among authors: billiet l. Cancer Immunol Res. 2024 Sep 3;12(9):1236-1251. doi: 10.1158/2326-6066.CIR-23-0677. Cancer Immunol Res. 2024. PMID: 38874582
Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly.
De Munter S, Van Parys A, Bral L, Ingels J, Goetgeluk G, Bonte S, Pille M, Billiet L, Weening K, Verhee A, Van der Heyden J, Taghon T, Leclercq G, Kerre T, Tavernier J, Vandekerckhove B. De Munter S, et al. Among authors: billiet l. Int J Mol Sci. 2020 Jan 30;21(3):883. doi: 10.3390/ijms21030883. Int J Mol Sci. 2020. PMID: 32019116 Free PMC article.
Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum.
Ingels J, De Cock L, Stevens D, Mayer RL, Théry F, Sanchez GS, Vermijlen D, Weening K, De Smet S, Lootens N, Brusseel M, Verstraete T, Buyle J, Van Houtte E, Devreker P, Heyns K, De Munter S, Van Lint S, Goetgeluk G, Bonte S, Billiet L, Pille M, Jansen H, Pascal E, Deseins L, Vantomme L, Verdonckt M, Roelandt R, Eekhout T, Vandamme N, Leclercq G, Taghon T, Kerre T, Vanommeslaeghe F, Dhondt A, Ferdinande L, Van Dorpe J, Desender L, De Ryck F, Vermassen F, Surmont V, Impens F, Menten B, Vermaelen K, Vandekerckhove B. Ingels J, et al. Among authors: billiet l. Cell Rep Med. 2024 May 21;5(5):101516. doi: 10.1016/j.xcrm.2024.101516. Epub 2024 Apr 15. Cell Rep Med. 2024. PMID: 38626769 Free PMC article. Clinical Trial.
Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials.
Ingels J, De Cock L, Mayer RL, Devreker P, Weening K, Heyns K, Lootens N, De Smet S, Brusseel M, De Munter S, Pille M, Billiet L, Goetgeluk G, Bonte S, Jansen H, Lint SV, Leclercq G, Taghon T, Menten B, Vermaelen K, Impens F, Vandekerckhove B. Ingels J, et al. Among authors: billiet l. Cytotherapy. 2022 Feb;24(2):213-222. doi: 10.1016/j.jcyt.2021.08.005. Epub 2021 Oct 22. Cytotherapy. 2022. PMID: 34696961 Free article.
78 results