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Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract.
Çalışkan DM, Kumar S, Hinse S, Schughart K, Wiewrodt R, Fischer S, Krueger V, Wiebe K, Barth P, Mellmann A, Ludwig S, Brunotte L. Çalışkan DM, et al. Among authors: schughart k. Emerg Microbes Infect. 2024 Dec;13(1):2402868. doi: 10.1080/22221751.2024.2402868. Epub 2024 Sep 23. Emerg Microbes Infect. 2024. PMID: 39248230 Free PMC article.
Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier.
Faist A, Schloer S, Mecate-Zambrano A, Janowski J, Schreiber A, Boergeling Y, Conrad BCG, Kumar S, Toebben L, Schughart K, Baumgardt M, Kessler M, Hoenzke K, Hocke A, Trautmann M, Hartmann W, Kato H, Rescher U, Christersson A, Kuehn J, Mellmann A, Wolff T, Kuempers P, Rovas A, Wiewrodt R, Wiebe K, Barth P, Ludwig S, Brunotte L. Faist A, et al. Among authors: schughart k. Antiviral Res. 2023 Jan;209:105475. doi: 10.1016/j.antiviral.2022.105475. Epub 2022 Nov 21. Antiviral Res. 2023. PMID: 36423831 Free PMC article.
Host transcriptomics and machine learning for secondary bacterial infections in patients with COVID-19: a prospective, observational cohort study.
Carney M, Pelaia TM, Chew T, Teoh S, Phu A, Kim K, Wang Y, Iredell J, Zerbib Y, McLean A, Schughart K, Tang B, Shojaei M, Short KR; PREDICT-19 consortium. Carney M, et al. Among authors: schughart k. Lancet Microbe. 2024 Mar;5(3):e272-e281. doi: 10.1016/S2666-5247(23)00363-4. Epub 2024 Feb 1. Lancet Microbe. 2024. PMID: 38310908 Free article.
Blood transcriptome responses in patients correlate with severity of COVID-19 disease.
Wang Y, Schughart K, Pelaia TM, Chew T, Kim K, Karvunidis T, Knippenberg B, Teoh S, Phu AL, Short KR, Iredell J, Thevarajan I, Audsley J, Macdonald S, Burcham J, McLean A; PREDICT-19 consortium; Tang B, Shojaei M. Wang Y, et al. Among authors: schughart k. Front Immunol. 2023 Jan 20;13:1043219. doi: 10.3389/fimmu.2022.1043219. eCollection 2022. Front Immunol. 2023. PMID: 36741372 Free PMC article.
156 results