Yu H - Search Results

1

Integrated Thermal Proteome Profiling and Affinity Ultrafiltration Mass Spectrometry (iTPAUMS): A Novel Paradigm for Elucidating the Mechanism of Action of Natural Products.

Yu H, Chen Y, Wang Y, Fu W, Xu R, Liu J, Chen Y, Liu X, Wu Y, Xu T. Yu H, et al. Anal Chem. 2024 Oct 8;96(40):15980-15990. doi: 10.1021/acs.analchem.4c03398. Epub 2024 Sep 10. Anal Chem. 2024. PMID: 39252608

2

Uncovering the antitumor effects and mechanisms of Shikonin against colon cancer on comprehensive analysis.

Chen Y, Si L, Zhang J, Yu H, Liu X, Chen Y, Wu Y. Chen Y, et al. Among authors: yu h. Phytomedicine. 2021 Feb;82:153460. doi: 10.1016/j.phymed.2021.153460. Epub 2021 Jan 8. Phytomedicine. 2021. PMID: 33476976

3

Exploration of the anti-inflammatory mechanism of Lanqin oral solution based on the network pharmacology analysis optimized by Q-markers selection.

Ma H, Fu W, Yu H, Xu Y, Xiao L, Zhang Y, Wu Y, Liu X, Chen Y, Xu T. Ma H, et al. Among authors: yu h. Comput Biol Med. 2023 Mar;154:106607. doi: 10.1016/j.compbiomed.2023.106607. Epub 2023 Jan 23. Comput Biol Med. 2023. PMID: 36731363

4

Discovery of a potent and selective PARP1 degrader promoting cell cycle arrest via intercepting CDC25C-CDK1 axis for treating triple-negative breast cancer.

Wu Y, Wu M, Zheng X, Yu H, Mao X, Jin Y, Wang Y, Pang A, Zhang J, Zeng S, Xu T, Chen Y, Zhang B, Lin N, Dai H, Wang Y, Yao X, Dong X, Huang W, Che J. Wu Y, et al. Among authors: yu h. Bioorg Chem. 2024 Jan;142:106952. doi: 10.1016/j.bioorg.2023.106952. Epub 2023 Nov 8. Bioorg Chem. 2024. PMID: 37952486

5

Network pharmacology combined with affinity ultrafiltration to elucidate the potential compounds of Shaoyao Gancao Fuzi Decoction for the treatment of rheumatoid arthritis.

Fu W, Shentu C, Chen D, Qiu J, Zong C, Yu H, Zhang Y, Chen Y, Liu X, Xu T. Fu W, et al. Among authors: yu h. J Ethnopharmacol. 2024 Aug 10;330:118268. doi: 10.1016/j.jep.2024.118268. Epub 2024 Apr 26. J Ethnopharmacol. 2024. PMID: 38677569

6

Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological Tumors.

Duan H, Zhang J, Gui R, Lu Y, Pang A, Chen B, Shen L, Yu H, Li J, Xu T, Wang Y, Yao X, Zhang B, Lin N, Dong X, Zhou Y, Che J. Duan H, et al. Among authors: yu h. J Med Chem. 2024 Jul 11;67(13):11326-11353. doi: 10.1021/acs.jmedchem.4c00883. Epub 2024 Jun 24. J Med Chem. 2024. PMID: 38913763

7

Integrated metabolomics and proteomics analyses to reveal anticancer mechanism of hemp oil extract in colorectal cancer.

Yu H, Chen Y, Deng J, Cai G, Fu W, Shentu C, Xu Y, Liu J, Zhou Y, Luo Y, Chen Y, Liu X, Wu Y, Xu T. Yu H, et al. J Pharm Biomed Anal. 2024 Oct 15;249:116379. doi: 10.1016/j.jpba.2024.116379. Epub 2024 Jul 22. J Pharm Biomed Anal. 2024. PMID: 39059180

8

Discovery of an Exceptionally Orally Bioavailable and Potent HPK1 PROTAC with Enhancement of Antitumor Efficacy of Anti-PD-L1 Therapy.

Wu M, Wu Y, Jin Y, Mao X, Zeng S, Yu H, Zhang J, Jin Y, Wu Y, Xu T, Chen Y, Wang Y, Yao X, Che J, Huang W, Dong X. Wu M, et al. Among authors: yu h. J Med Chem. 2024 Aug 22;67(16):13852-13878. doi: 10.1021/acs.jmedchem.4c00644. Epub 2024 Jul 31. J Med Chem. 2024. PMID: 39084610

9

Discovery of a potent PARP1 PROTAC as a chemosensitizer for the treatment of colorectal cancer.

Wu M, Jiang Y, Zhang D, Wu Y, Jin Y, Liu T, Mao X, Yu H, Xu T, Chen Y, Huang W, Che J, Zhang B, Liu T, Lin N, Dong X. Wu M, et al. Among authors: yu h. Eur J Med Chem. 2025 Jan 15;282:117062. doi: 10.1016/j.ejmech.2024.117062. Epub 2024 Nov 17. Eur J Med Chem. 2025. PMID: 39602992

10

DNA Methylation of Somatic Tissues in Oysters is Influenced by Sex and Heredity.

Teng W, Xu C, Liu S, Yu H, Kong L, Li Q. Teng W, et al. Among authors: yu h. Mar Biotechnol (NY). 2025 Jan 14;27(1):31. doi: 10.1007/s10126-024-10409-6. Mar Biotechnol (NY). 2025. PMID: 39808191

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