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Page 1
Biological Insights from Schizophrenia-associated Loci in Ancestral Populations.
Bigdeli TB, Chatzinakos C, Bendl J, Barr PB, Venkatesh S, Gorman BR, Clarence T, Genovese G, Iyegbe CO, Peterson RE, Kolokotronis SO, Burstein D, Meyers JL, Li Y, Rajeevan N, Sayward F, Cheung KH; Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS); Consortium on the Genomics of Schizophrenia (COGS); Genomic Psychiatry Cohort (GPC) Investigators; DeLisi LE, Kosten TR, Zhao H, Achtyes E, Buckley P, Malaspina D, Lehrer D, Rapaport MH, Braff DL, Pato MT, Fanous AH, Pato CN; PsychAD Consortium; Cooperative Studies Program (CSP) #572; Million Veteran Program (MVP); Huang GD, Muralidhar S, Michael Gaziano J, Pyarajan S, Girdhar K, Lee D, Hoffman GE, Aslan M, Fullard JF, Voloudakis G, Harvey PD, Roussos P. Bigdeli TB, et al. Among authors: iyegbe co. medRxiv [Preprint]. 2024 Aug 28:2024.08.27.24312631. doi: 10.1101/2024.08.27.24312631. medRxiv. 2024. PMID: 39252912 Free PMC article. Preprint.
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, … See abstract for full author list ➔ Trubetskoy V, et al. Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. Epub 2022 Apr 8. Nature. 2022. PMID: 35396580 Free PMC article.
Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells.
Bhat A, Irizar H, Couch ACM, Raval P, Duarte RRR, Dutan Polit L, Hanger B, Powell T, Deans PJM, Shum C, Nagy R, McAlonan G, Iyegbe CO, Price J, Bramon E, Bhattacharyya S, Vernon AC, Srivastava DP. Bhat A, et al. Among authors: iyegbe co. Brain Behav Immun. 2022 Oct;105:82-97. doi: 10.1016/j.bbi.2022.06.010. Epub 2022 Jun 16. Brain Behav Immun. 2022. PMID: 35716830 Free PMC article.
Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
Bigdeli TB, Genovese G, Georgakopoulos P, Meyers JL, Peterson RE, Iyegbe CO, Medeiros H, Valderrama J, Achtyes ED, Kotov R, Stahl EA, Abbott C, Azevedo MH, Belliveau RA, Bevilacqua E, Bromet EJ, Byerley W, Carvalho CB, Chapman SB, DeLisi LE, Dumont AL, O'Dushlaine C, Evgrafov OV, Fochtmann LJ, Gage D, Kennedy JL, Kinkead B, Macedo A, Moran JL, Morley CP, Dewan MJ, Nemesh J, Perkins DO, Purcell SM, Rakofsky JJ, Scolnick EM, Sklar BM, Sklar P, Smoller JW, Sullivan PF, Macciardi F, Marder SR, Gur RC, Gur RE, Braff DL; Consortium on the Genetics of Schizophrenia (COGS) Investigators; Nicolini H, Escamilla MA, Vawter MP, Sobell JL, Malaspina D, Lehrer DS, Buckley PF, Rapaport MH, Knowles JA; Genomic Psychiatry Cohort (GPC) Consortium; Fanous AH, Pato MT, McCarroll SA, Pato CN. Bigdeli TB, et al. Among authors: iyegbe co. Mol Psychiatry. 2020 Oct;25(10):2455-2467. doi: 10.1038/s41380-019-0517-y. Epub 2019 Oct 7. Mol Psychiatry. 2020. PMID: 31591465 Free PMC article.
Differential gene expression analysis in blood of first episode psychosis patients.
Leirer DJ, Iyegbe CO, Di Forti M, Patel H, Carra E, Fraietta S, Colizzi M, Mondelli V, Quattrone D, Lally J, Ajnakina O, Lee SH, Curtis CJ, Breen G, Pariante C, Aitchison K, Dazzan P, Murray RM, Dobson RJB, Newhouse SJ. Leirer DJ, et al. Among authors: iyegbe co. Schizophr Res. 2019 Jul;209:88-97. doi: 10.1016/j.schres.2019.05.011. Epub 2019 May 19. Schizophr Res. 2019. PMID: 31113746 Free PMC article.