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Single-cell transcriptomics reveals subset-specific metabolic profiles underpinning the bronchial epithelial response to flagellin.
Ramirez-Moral I, Schuurman AR, van Linge CCA, Butler JM, Yu X, de Haan K, van Leeuwen S, de Vos AF, de Jong MD, Vieira Braga FA, van der Poll T. Ramirez-Moral I, et al. Among authors: van linge cca, van leeuwen s, van der poll t. iScience. 2024 Aug 3;27(9):110662. doi: 10.1016/j.isci.2024.110662. eCollection 2024 Sep 20. iScience. 2024. PMID: 39252969 Free PMC article.
Inflammatory and glycolytic programs underpin a primed blood neutrophil state in patients with pneumonia.
Schuurman AR, Butler JM, Michels EHA, Otto NA, Brands X, Haak BW, Uhel F, Klarenbeek AM, Faber DR, Schomakers BV, van Weeghel M, de Vos AF, Scicluna BP, Houtkooper RH, Wiersinga WJ, van der Poll T. Schuurman AR, et al. Among authors: van weeghel m, van der poll t. iScience. 2023 Jun 19;26(7):107181. doi: 10.1016/j.isci.2023.107181. eCollection 2023 Jul 21. iScience. 2023. PMID: 37496676 Free PMC article.
Embracing complexity in sepsis.
Schuurman AR, Sloot PMA, Wiersinga WJ, van der Poll T. Schuurman AR, et al. Among authors: van der poll t. Crit Care. 2023 Mar 11;27(1):102. doi: 10.1186/s13054-023-04374-0. Crit Care. 2023. PMID: 36906606 Free PMC article. Review.
Thrombocytopenia is associated with a dysregulated host response in severe COVID-19.
Appelman B, Michels EHA, de Brabander J, Peters-Sengers H, van Amstel RBE, Noordzij SM, Klarenbeek AM, van Linge CCA, Chouchane O, Schuurman AR, Reijnders TDY, Douma RA, Bos LDJ; Amsterdam UMC COVID-19 Biobank study group; CovidPredict study group; Wiersinga WJ, van der Poll T. Appelman B, et al. Among authors: van linge cca, van der poll t, van amstel rbe. Thromb Res. 2023 Sep;229:187-197. doi: 10.1016/j.thromres.2023.07.008. Epub 2023 Jul 19. Thromb Res. 2023. PMID: 37541167 Free article.
The shifting lipidomic landscape of blood monocytes and neutrophils during pneumonia.
Schuurman AR, Chouchane O, Butler JM, Peters-Sengers H, Joosten S, Brands X, Haak BW, Otto NA, Uhel F, Klarenbeek A, van Linge CC, van Kampen A, Pras-Raves M, van Weeghel M, van Eijk M, Ferraz MJ, Faber DR, de Vos A, Scicluna BP, Vaz FM, Wiersinga WJ, van der Poll T. Schuurman AR, et al. Among authors: van weeghel m, van der poll t, van kampen a, van linge cc, van eijk m. JCI Insight. 2024 Feb 22;9(4):e164400. doi: 10.1172/jci.insight.164400. JCI Insight. 2024. PMID: 38385743 Free PMC article.
Age-related changes in plasma biomarkers and their association with mortality in COVID-19.
Michels EHA, Appelman B, de Brabander J, van Amstel RBE, Chouchane O, van Linge CCA, Schuurman AR, Reijnders TDY, Sulzer TAL, Klarenbeek AM, Douma RA; Amsterdam UMC COVID-19 Biobank Study Group; Bos LDJ, Wiersinga WJ, Peters-Sengers H, van der Poll T; Amsterdam UMC COVID-19 Biobank Study Group; van Agtmael M, Algera AG, Appelman B, van Baarle F, Beudel M, Bogaard HJ, Bomers M, Bonta P, Bos L, Botta M, de Brabander J, de Bree G, de Bruin S, Bugiani M, Bulle E, Buis DTP, Chouchane O, Cloherty A, Dijkstra M, Dongelmans DA, Dujardin RWG, Elbers P, Fleuren L, Geerlings S, Geijtenbeek T, Girbes A, Goorhuis B, Grobusch MP, Hagens L, Hamann J, Harris V, Hemke R, Hermans SM, Heunks L, Hollmann M, Horn J, Hovius JW, de Jong HK, de Jong MD, Koning R, Lemkes B, Lim EHT, van Mourik N, Nellen J, Nossent EJ, Olie S, Paulus F, Peters E, Pina-Fuentes DAI, van der Poll T, Preckel B, Prins JM, Raasveld J, Reijnders T, de Rotte MCFJ, Schinkel M, Schultz MJ, Schrauwen FAP, Schuurman A, Schuurmans J, Sigaloff K, Slim MA, Smeele P, Smit M, Stijnis CS, Stilma W, Teunissen C, Thoral P, Tsonas AM, Tuinman PR, van der Valk M, Veelo DP, Volleman C, de V… See abstract for full author list ➔ Michels EHA, et al. Among authors: van agtmael m, van linge cca, van mourik n, van de beek d, van vugt m, van der poll t, van baarle f, van der valk m, van amstel rbe. Eur Respir J. 2023 Jul 7;62(1):2300011. doi: 10.1183/13993003.00011-2023. Print 2023 Jul. Eur Respir J. 2023. PMID: 37080568 Free PMC article.
Host Response Changes and Their Association with Mortality in COVID-19 Patients with Lymphopenia.
Michels EHA, Appelman B, de Brabander J, van Amstel RBE, van Linge CCA, Chouchane O, Reijnders TDY, Schuurman AR, Sulzer TAL, Klarenbeek AM, Douma RA, Bos LDJ, Wiersinga WJ, Peters-Sengers H, van der Poll T; Amsterdam UMC COVID-19 Biobank Study Group. Michels EHA, et al. Among authors: van linge cca, van der poll t, van amstel rbe. Am J Respir Crit Care Med. 2024 Feb 15;209(4):402-416. doi: 10.1164/rccm.202305-0890OC. Am J Respir Crit Care Med. 2024. PMID: 37948687 Free PMC article.
Platelets of COVID-19 patients display mitochondrial dysfunction, oxidative stress, and energy metabolism failure compatible with cell death.
Léopold V, Chouchane O, Butler JM, Schuurman AR, Michels EHA, de Brabander J, Schomakers BV, van Weeghel M, Picavet-Havik DI, Grootemaat AE, Douma RA, Reijnders TDY, Klarenbeek AM, Appelman B; Amsterdam University Medical Center COVID-19 Biobank Study [email protected]; Wiersinga WJ, van der Wel NN, den Dunnen J, Houtkooper RH, Van't Veer C, van der Poll T; Amsterdam University Medical Center COVID-19 Biobank Study Group. Léopold V, et al. Among authors: van weeghel m, van der wel nn, van t veer c, van der poll t. Res Pract Thromb Haemost. 2023 Sep 28;7(7):102213. doi: 10.1016/j.rpth.2023.102213. eCollection 2023 Oct. Res Pract Thromb Haemost. 2023. PMID: 38077825 Free PMC article.
1,072 results