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Page 1
Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii.
Baker S, Krishna A, Higham S, Naydenova P, O'Leary S, Scott JB, Harcourt K, Forrest S, Goulding D, Thi Nguyen TN, Toan ND, Alekseeva E, Zhou Q, Andreozzi I, Sobotic B, Craig H, Wong V, Forrest-Owen N, Sanchez DM, Pearce C, Roberts L, Watson S, Clare S, Torok ME, Dougan G, Kellam P, Tregoning JS, Reece ST. Baker S, et al. Among authors: harcourt k. Nat Commun. 2024 Sep 12;15(1):7979. doi: 10.1038/s41467-024-52357-8. Nat Commun. 2024. PMID: 39266557 Free PMC article.
An invariant Trypanosoma vivax vaccine antigen induces protective immunity.
Autheman D, Crosnier C, Clare S, Goulding DA, Brandt C, Harcourt K, Tolley C, Galaway F, Khushu M, Ong H, Romero-Ramirez A, Duffy CW, Jackson AP, Wright GJ. Autheman D, et al. Among authors: harcourt k. Nature. 2021 Jul;595(7865):96-100. doi: 10.1038/s41586-021-03597-x. Epub 2021 May 26. Nature. 2021. PMID: 34040257
An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation.
Van Puyvelde S, Pickard D, Vandelannoote K, Heinz E, Barbé B, de Block T, Clare S, Coomber EL, Harcourt K, Sridhar S, Lees EA, Wheeler NE, Klemm EJ, Kuijpers L, Mbuyi Kalonji L, Phoba MF, Falay D, Ngbonda D, Lunguya O, Jacobs J, Dougan G, Deborggraeve S. Van Puyvelde S, et al. Among authors: harcourt k. Nat Commun. 2019 Sep 19;10(1):4280. doi: 10.1038/s41467-019-11844-z. Nat Commun. 2019. PMID: 31537784 Free PMC article.
Tissue-resident B cells orchestrate macrophage polarisation and function.
Suchanek O, Ferdinand JR, Tuong ZK, Wijeyesinghe S, Chandra A, Clauder AK, Almeida LN, Clare S, Harcourt K, Ward CJ, Bashford-Rogers R, Lawley T, Manz RA, Okkenhaug K, Masopust D, Clatworthy MR. Suchanek O, et al. Among authors: harcourt k. Nat Commun. 2023 Nov 4;14(1):7081. doi: 10.1038/s41467-023-42625-4. Nat Commun. 2023. PMID: 37925420 Free PMC article.
Identification of gut microbial species linked with disease variability in a widely used mouse model of colitis.
Forster SC, Clare S, Beresford-Jones BS, Harcourt K, Notley G, Stares MD, Kumar N, Soderholm AT, Adoum A, Wong H, Morón B, Brandt C, Dougan G, Adams DJ, Maloy KJ, Pedicord VA, Lawley TD. Forster SC, et al. Among authors: harcourt k. Nat Microbiol. 2022 Apr;7(4):590-599. doi: 10.1038/s41564-022-01094-z. Epub 2022 Apr 1. Nat Microbiol. 2022. PMID: 35365791 Free PMC article.
New Variant of Multidrug-Resistant Salmonella enterica Serovar Typhimurium Associated with Invasive Disease in Immunocompromised Patients in Vietnam.
Mather AE, Phuong TLT, Gao Y, Clare S, Mukhopadhyay S, Goulding DA, Hoang NTD, Tuyen HT, Lan NPH, Thompson CN, Trang NHT, Carrique-Mas J, Tue NT, Campbell JI, Rabaa MA, Thanh DP, Harcourt K, Hoa NT, Trung NV, Schultsz C, Perron GG, Coia JE, Brown DJ, Okoro C, Parkhill J, Thomson NR, Chau NVV, Thwaites GE, Maskell DJ, Dougan G, Kenney LJ, Baker S. Mather AE, et al. Among authors: harcourt k. mBio. 2018 Sep 4;9(5):e01056-18. doi: 10.1128/mBio.01056-18. mBio. 2018. PMID: 30181247 Free PMC article.
Adaptation of host transmission cycle during Clostridium difficile speciation.
Kumar N, Browne HP, Viciani E, Forster SC, Clare S, Harcourt K, Stares MD, Dougan G, Fairley DJ, Roberts P, Pirmohamed M, Clokie MRJ, Jensen MBF, Hargreaves KR, Ip M, Wieler LH, Seyboldt C, Norén T, Riley TV, Kuijper EJ, Wren BW, Lawley TD. Kumar N, et al. Among authors: harcourt k. Nat Genet. 2019 Sep;51(9):1315-1320. doi: 10.1038/s41588-019-0478-8. Epub 2019 Aug 12. Nat Genet. 2019. PMID: 31406348
The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi-like protein tail fibre.
Dunstan RA, Pickard D, Dougan S, Goulding D, Cormie C, Hardy J, Li F, Grinter R, Harcourt K, Yu L, Song J, Schreiber F, Choudhary J, Clare S, Coulibaly F, Strugnell RA, Dougan G, Lithgow T. Dunstan RA, et al. Among authors: harcourt k. Mol Microbiol. 2019 Dec;112(6):1831-1846. doi: 10.1111/mmi.14396. Epub 2019 Oct 9. Mol Microbiol. 2019. PMID: 31556164 Free article.
64 results