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Pyrimidine-triazole-tethered tert-butyl-piperazine-carboxylate suppresses breast cancer by targeting estrogen receptor signaling and β-catenin activation.
Yuan J, Yang L, Li Z, Zhang H, Wang Q, Wang B, Chinnathambi A, Govindasamy C, Basappa S, Nagaraja O, Madegowda M, Beeraka NM, Nikolenko VN, Wang M, Wang G, Rangappa KS, Basappa B. Yuan J, et al. Among authors: madegowda m. IUBMB Life. 2024 Dec;76(12):1309-1324. doi: 10.1002/iub.2913. Epub 2024 Sep 14. IUBMB Life. 2024. PMID: 39275910
Discovery of oxazine-linked pyrimidine as an inhibitor of breast cancer growth and metastasis by abrogating NF-κB activation.
Yuan J, Narasimhachar BC, Ravish A, Yang L, Zhang H, Wang Q, Li Z, Huang J, Wang B, Wang G, Kumar Harish K, Chinnathambi A, Govindasamy C, Madegowda M, Basappa B. Yuan J, et al. Among authors: madegowda m. Front Oncol. 2024 Jul 29;14:1390992. doi: 10.3389/fonc.2024.1390992. eCollection 2024. Front Oncol. 2024. PMID: 39135991 Free PMC article.
De Novo Design of Imidazopyridine-Tethered Pyrazolines That Target Phosphorylation of STAT3 in Human Breast Cancer Cells.
Ravish A, Shivakumar R, Xi Z, Yang MH, Yang JR, Swamynayaka A, Nagaraja O, Madegowda M, Chinnathambi A, Alharbi SA, Pandey V, Sethi G, Ahn KS, Lobie PE, Basappa B. Ravish A, et al. Among authors: madegowda m. Bioengineering (Basel). 2023 Jan 24;10(2):159. doi: 10.3390/bioengineering10020159. Bioengineering (Basel). 2023. PMID: 36829653 Free PMC article.
Oxazine drug-seed induces paraptosis and apoptosis through reactive oxygen species/JNK pathway in human breast cancer cells.
Kim NY, Dukanya D, Sethi G, Girimanchanaika SS, Yang J, Nagaraja O, Swamynayaka A, Vishwanath D, Venkantesha K, Basappa S, Chinnathambi A, Alharbi SA, Madegowda M, Sukhorukov A, Pandey V, Lobie PE, Basappa B, Ahn KS. Kim NY, et al. Among authors: madegowda m. Transl Oncol. 2024 Nov;49:102101. doi: 10.1016/j.tranon.2024.102101. Epub 2024 Aug 18. Transl Oncol. 2024. PMID: 39159553 Free PMC article.
Nano-Zirconium Dioxide Catalyzed Multicomponent Synthesis of Bioactive Pyranopyrazoles That Target Cyclin Dependent Kinase 1 in Human Breast Cancer Cells.
Basappa B, Poonacha LK, Xi Z, Vishwanath D, Yang JR, Nagaraja O, Swamynayaka A, Madegowda M, Chinnathambi A, Alharbi SA, Gurudatt DM, Pandey V, Shivananju N, Ahn KS, Sethi G, Lobie PE, Shubha PB. Basappa B, et al. Among authors: madegowda m. Biomedicines. 2023 Jan 10;11(1):172. doi: 10.3390/biomedicines11010172. Biomedicines. 2023. PMID: 36672680 Free PMC article.
A novel drug prejudice scaffold-imidazopyridine-conjugate can promote cell death in a colorectal cancer model by binding to β-catenin and suppressing the Wnt signaling pathway.
Yang MH, Basappa B, Deveshegowda SN, Ravish A, Mohan A, Nagaraja O, Madegowda M, Rangappa KS, Deivasigamani A, Pandey V, Lobie PE, Hui KM, Sethi G, Ahn KS. Yang MH, et al. Among authors: madegowda m. J Adv Res. 2024 Jul 25:S2090-1232(24)00305-9. doi: 10.1016/j.jare.2024.07.022. Online ahead of print. J Adv Res. 2024. PMID: 39067696 Free article.
Development of 1-(4-(Substituted)piperazin-1-yl)-2-((2-((4-methoxybenzyl)thio)pyrimidin-4-yl)oxy)ethanones That Target Poly (ADP-Ribose) Polymerase in Human Breast Cancer Cells.
Deveshegowda SN, Metri PK, Shivakumar R, Yang JR, Rangappa S, Swamynayaka A, Shanmugam MK, Nagaraja O, Madegowda M, Babu Shubha P, Chinnathambi A, Alharbi SA, Pandey V, Ahn KS, Lobie PE, Basappa B. Deveshegowda SN, et al. Among authors: madegowda m. Molecules. 2022 Apr 29;27(9):2848. doi: 10.3390/molecules27092848. Molecules. 2022. PMID: 35566199 Free PMC article.
25 results