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Normothermic ex vivo kidney perfusion preserves mitochondrial and graft function after warm ischemia and is further enhanced by AP39.
Kawamura M, Parmentier C, Ray S, Clotet-Freixas S, Leung S, John R, Mazilescu L, Nogueira E, Noguchi Y, Goto T, Arulratnam B, Ganesh S, Tamang T, Lees K, Reichman TW, Andreazza AC, Kim PK, Konvalinka A, Selzner M, Robinson LA. Kawamura M, et al. Among authors: robinson la. Nat Commun. 2024 Sep 15;15(1):8086. doi: 10.1038/s41467-024-52140-9. Nat Commun. 2024. PMID: 39278958 Free PMC article.
Normothermic Ex Vivo Kidney Perfusion Reduces Warm Ischemic Injury of Porcine Kidney Grafts Retrieved After Circulatory Death.
Hamar M, Urbanellis P, Kaths MJ, Kollmann D, Linares I, Ganesh S, Wiebe A, Cen JY, Yip P, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli D, Grant D, Robinson LA, Selzner M. Hamar M, et al. Among authors: robinson la. Transplantation. 2018 Aug;102(8):1262-1270. doi: 10.1097/TP.0000000000002245. Transplantation. 2018. PMID: 29683999
Normothermic Ex Vivo Kidney Perfusion Improves Early DCD Graft Function Compared With Hypothermic Machine Perfusion and Static Cold Storage.
Urbanellis P, Hamar M, Kaths JM, Kollmann D, Linares I, Mazilescu L, Ganesh S, Wiebe A, Yip PM, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli DJ, Robinson LA, Selzner M. Urbanellis P, et al. Among authors: robinson la. Transplantation. 2020 May;104(5):947-955. doi: 10.1097/TP.0000000000003066. Transplantation. 2020. PMID: 31815900
Normothermic Ex-vivo Kidney Perfusion in a Porcine Auto-Transplantation Model Preserves the Expression of Key Mitochondrial Proteins: An Unbiased Proteomics Analysis.
McEvoy CM, Clotet-Freixas S, Tokar T, Pastrello C, Reid S, Batruch I, RaoPeters AAE, Kaths JM, Urbanellis P, Farkona S, Van JAD, Urquhart BL, John R, Jurisica I, Robinson LA, Selzner M, Konvalinka A. McEvoy CM, et al. Among authors: robinson la. Mol Cell Proteomics. 2021;20:100101. doi: 10.1016/j.mcpro.2021.100101. Epub 2021 May 23. Mol Cell Proteomics. 2021. PMID: 34033948 Free PMC article.
Prolonged warm ischemia time leads to severe renal dysfunction of donation-after-cardiac death kidney grafts.
Urbanellis P, Mazilescu L, Kollmann D, Linares-Cervantes I, Kaths JM, Ganesh S, Oquendo F, Sharma M, Goto T, Noguchi Y, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli D, Robinson LA, Selzner M. Urbanellis P, et al. Among authors: robinson la. Sci Rep. 2021 Sep 9;11(1):17930. doi: 10.1038/s41598-021-97078-w. Sci Rep. 2021. PMID: 34504136 Free PMC article.
Combining Oxygenated Cold Perfusion With Normothermic Ex Vivo Perfusion Improves the Outcome of Donation After Circulatory Death Porcine Kidney Transplantation.
Mazilescu LI, Goto T, John R, Rosales R, Ganesh S, Yu F, Noguchi Y, Kawamura M, Dezard V, Gao F, Urbanellis P, Parmentier C, Konvalinka A, Bagli DJ, Reichman TW, Robinson LA, Selzner M. Mazilescu LI, et al. Among authors: robinson la. Transplantation. 2024 Jan 1;108(1):184-191. doi: 10.1097/TP.0000000000004734. Epub 2023 Dec 13. Transplantation. 2024. PMID: 37505906
Significant Dysfunction of Kidney Grafts Exposed to Prolonged Warm Ischemia Is Minimized Through Normothermic Ex Vivo Kidney Perfusion.
Urbanellis P, Kollmann D, Linares I, Ganesh S, Oquendo F, Mazilescu L, Goto T, Noguchi Y, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli D, Selzner M, Robinson LA. Urbanellis P, et al. Among authors: robinson la. Transplant Direct. 2020 Jul 22;6(8):e587. doi: 10.1097/TXD.0000000000001030. eCollection 2020 Aug. Transplant Direct. 2020. PMID: 32766435 Free PMC article.
Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation.
Kaths JM, Hamar M, Echeverri J, Linares I, Urbanellis P, Cen JY, Ganesh S, Dingwell LS, Yip P, John R, Bagli D, Mucsi I, Ghanekar A, Grant D, Robinson LA, Selzner M. Kaths JM, et al. Among authors: robinson la. Am J Transplant. 2018 Mar;18(3):580-589. doi: 10.1111/ajt.14491. Epub 2017 Oct 16. Am J Transplant. 2018. PMID: 28889600 Free article.
348 results