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438 results

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Multiarm, non-randomised, single-centre feasibility study-investigation of the differential biology between benign and malignant renal masses using advanced magnetic resonance imaging techniques (IBM-Renal): protocol.
Horvat-Menih I, McLean MA, Zamora-Morales MJ, Wylot M, Kaggie J, Khan AS, Gill AB, Duarte J, Locke MJ, Mendichovszky I, Li H, Priest AN, Warren AY, Welsh SJ, Jones JO, Armitage JN, Mitchell TJ, Stewart GD, Gallagher FA. Horvat-Menih I, et al. Among authors: mitchell tj. BMJ Open. 2024 Oct 26;14(10):e083980. doi: 10.1136/bmjopen-2024-083980. BMJ Open. 2024. PMID: 39461869 Free PMC article.
VHL synthetic lethality screens uncover CBF-β as a negative regulator of STING.
Bertlin JAC, Pauzaite T, Liang Q, Wit N, Williamson JC, Sia JJ, Matheson NJ, Ortmann BM, Mitchell TJ, Speak AO, Zhang Q, Nathan JA. Bertlin JAC, et al. Among authors: mitchell tj. bioRxiv [Preprint]. 2024 Sep 6:2024.09.03.610968. doi: 10.1101/2024.09.03.610968. bioRxiv. 2024. PMID: 39282259 Free PMC article. Preprint.
Multifocal, multiphenotypic tumours arising from an MTOR mutation acquired in early embryogenesis.
Pacyna CN, Anandapadamanaban M, Loudon KW, Hay IM, Perisic O, Li R, Byrne M, Allen L, Roberts K, Hooks Y, Warren AY, Stewart GD, Clatworthy MR, Teichmann SA, Behjati S, Campbell PJ, Williams RL, Mitchell TJ. Pacyna CN, et al. Among authors: mitchell tj. Oncogene. 2024 Oct;43(44):3268-3276. doi: 10.1038/s41388-024-03137-7. Epub 2024 Sep 13. Oncogene. 2024. PMID: 39271965 Free PMC article.
'Case of the Month' from Addenbrooke's Hospital, Cambridge, UK: surgery after near complete response to combined immunotherapy and tyrosine kinase inhibitor therapy for metastatic renal cell carcinoma with inferior vena cava tumour thrombus.
Blackmur JP, Armitage JN, Jones JO, Riddick ACP, Mitchell TJ, Ince WHJ, Appukutty S, Warren AY, Fife K, O'Carrigan B, Stewart GD. Blackmur JP, et al. Among authors: mitchell tj. BJU Int. 2024 Jul 16. doi: 10.1111/bju.16472. Online ahead of print. BJU Int. 2024. PMID: 39014977 No abstract available.
High-resolution and highly accelerated MRI T2 mapping as a tool to characterise renal tumour subtypes and grades.
Horvat-Menih I, Li H, Priest AN, Li S, Gill AB, Mendichovszky IA, Francis ST, Warren AY, O'Carrigan B, Welsh SJ, Jones JO, Riddick ACP, Armitage JN, Mitchell TJ, Stewart GD, Gallagher FA. Horvat-Menih I, et al. Among authors: mitchell tj. Eur Radiol Exp. 2024 Jul 10;8(1):76. doi: 10.1186/s41747-024-00476-8. Eur Radiol Exp. 2024. PMID: 38981998 Free PMC article.
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction.
Salcedo A, Tarabichi M, Buchanan A, Espiritu SMG, Zhang H, Zhu K, Ou Yang TH, Leshchiner I, Anastassiou D, Guan Y, Jang GH, Mootor MFE, Haase K, Deshwar AG, Zou W, Umar I, Dentro S, Wintersinger JA, Chiotti K, Demeulemeester J, Jolly C, Sycza L, Ko M; PCAWG Evolution and Heterogeneity Working Group; SMC-Het Participants; Wedge DC, Morris QD, Ellrott K, Van Loo P, Boutros PC. Salcedo A, et al. Nat Biotechnol. 2024 Jun 11. doi: 10.1038/s41587-024-02250-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 38862616
438 results