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903 results

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Page 1
Oncogenic p53 triggers amyloid aggregation of p63 and p73 liquid droplets.
Petronilho EC, de Andrade GC, de Sousa GDS, Almeida FP, Mota MF, Gomes AVDS, Pinheiro CHS, da Silva MC, Arruda HRS, Marques MA, Vieira TCRG, de Oliveira GAP, Silva JL. Petronilho EC, et al. Among authors: silva jl. Commun Chem. 2024 Sep 16;7(1):207. doi: 10.1038/s42004-024-01289-x. Commun Chem. 2024. PMID: 39284933 Free PMC article.
The Status of p53 Oligomeric and Aggregation States in Cancer.
de Oliveira GAP, Petronilho EC, Pedrote MM, Marques MA, Vieira TCRG, Cino EA, Silva JL. de Oliveira GAP, et al. Among authors: silva jl. Biomolecules. 2020 Apr 4;10(4):548. doi: 10.3390/biom10040548. Biomolecules. 2020. PMID: 32260447 Free PMC article. Review.
Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands.
Petronilho EC, Pedrote MM, Marques MA, Passos YM, Mota MF, Jakobus B, de Sousa GDS, Pereira da Costa F, Felix AL, Ferretti GDS, Almeida FP, Cordeiro Y, Vieira TCRG, de Oliveira GAP, Silva JL. Petronilho EC, et al. Among authors: silva jl. Chem Sci. 2021 Apr 26;12(21):7334-7349. doi: 10.1039/d1sc01739j. Chem Sci. 2021. PMID: 34163823 Free PMC article.
Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer.
Pedrote MM, de Oliveira GAP, Felix AL, Mota MF, Marques MA, Soares IN, Iqbal A, Norberto DR, Gomes AMO, Gratton E, Cino EA, Silva JL. Pedrote MM, et al. Among authors: silva jl. J Biol Chem. 2018 Jul 20;293(29):11374-11387. doi: 10.1074/jbc.RA118.003285. Epub 2018 May 31. J Biol Chem. 2018. PMID: 29853637 Free PMC article.
Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells.
Melo Dos Santos N, de Oliveira GAP, Ramos Rocha M, Pedrote MM, Diniz da Silva Ferretti G, Pereira Rangel L, Morgado-Diaz JA, Silva JL, Rodrigues Pereira Gimba E. Melo Dos Santos N, et al. Among authors: silva jl. J Biol Chem. 2019 Jun 14;294(24):9430-9439. doi: 10.1074/jbc.RA119.007566. Epub 2019 Apr 26. J Biol Chem. 2019. PMID: 31028175 Free PMC article.
Cryo-EM to visualize the structural organization of viruses.
de Oliveira GA, Silva JL. de Oliveira GA, et al. Among authors: silva jl. Curr Opin Virol. 2021 Aug;49:86-91. doi: 10.1016/j.coviro.2021.04.011. Epub 2021 May 28. Curr Opin Virol. 2021. PMID: 34058526 Review.
903 results