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Conformational ensembles in Klebsiella pneumoniae FimH impact uropathogenesis.
Lopatto EDB, Pinkner JS, Sanick DA, Potter RF, Liu LX, Bazán Villicaña J, Tamadonfar KO, Ye Y, Zimmerman MI, Gualberto NC, Dodson KW, Janetka JW, Hunstad DA, Hultgren SJ. Lopatto EDB, et al. Among authors: sanick da. Proc Natl Acad Sci U S A. 2024 Sep 24;121(39):e2409655121. doi: 10.1073/pnas.2409655121. Epub 2024 Sep 17. Proc Natl Acad Sci U S A. 2024. PMID: 39288182 Free PMC article.
Monoclonal antibodies targeting the FimH adhesin protect against uropathogenic E. coli UTI.
Lopatto EDB, Santiago-Borges JM, Sanick DA, Malladi SK, Azimzadeh PN, Timm MW, Fox IF, Schmitz AJ, Turner JS, Ahmed SS, Ortinau L, Gualberto NC, Pinkner JS, Dodson KW, Ellebedy AH, Kau AL, Hultgren SJ. Lopatto EDB, et al. Among authors: sanick da. bioRxiv [Preprint]. 2024 Dec 11:2024.12.10.627638. doi: 10.1101/2024.12.10.627638. bioRxiv. 2024. PMID: 39713358 Free PMC article. Preprint.