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Phosphoproteomics predict response to midostaurin plus chemotherapy in independent cohorts of FLT3-mutated acute myeloid leukaemia.
Borek WE, Nobre L, Pedicona SF, Campbell AE, Christopher JA, Nawaz N, Perkins DN, Moreno-Cardoso P, Kelsall J, Ferguson HR, Patel B, Gallipoli P, Arruda A, Ambinder AJ, Thompson A, Williamson A, Ghiaur G, Minden MD, Gribben JG, Britton DJ, Cutillas PR, Dokal AD. Borek WE, et al. Among authors: campbell ae. EBioMedicine. 2024 Oct;108:105316. doi: 10.1016/j.ebiom.2024.105316. Epub 2024 Sep 17. EBioMedicine. 2024. PMID: 39293215 Free PMC article.
Systematic analysis of nonsense variants uncovers peptide release rate as a novel modifier of nonsense-mediated mRNA decay.
Kolakada D, Fu R, Biziaev N, Shuvalov A, Lore M, Campbell AE, Cortázar MA, Sajek MP, Hesselberth JR, Mukherjee N, Alkalaeva E, Coban Akdemir ZH, Jagannathan S. Kolakada D, et al. Among authors: campbell ae. bioRxiv [Preprint]. 2024 Nov 10:2024.01.10.575080. doi: 10.1101/2024.01.10.575080. bioRxiv. 2024. PMID: 38260612 Free PMC article. Preprint.
A system of reporters for comparative investigation of EJC-independent and EJC-enhanced nonsense-mediated mRNA decay.
Kolakada D, Campbell AE, Baquero Galvis L, Li Z, Lore M, Jagannathan S. Kolakada D, et al. Among authors: campbell ae. bioRxiv [Preprint]. 2023 Nov 15:2023.11.14.567061. doi: 10.1101/2023.11.14.567061. bioRxiv. 2023. Update in: Nucleic Acids Res. 2024 Apr 12;52(6):e34. doi: 10.1093/nar/gkae121 PMID: 38014198 Free PMC article. Updated. Preprint.
The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs.
Hamm DC, Paatela EM, Bennett SR, Wong CJ, Campbell AE, Wladyka CL, Smith AA, Jagannathan S, Hsieh AC, Tapscott SJ. Hamm DC, et al. Among authors: campbell ae. PLoS Biol. 2023 Sep 25;21(9):e3002317. doi: 10.1371/journal.pbio.3002317. eCollection 2023 Sep. PLoS Biol. 2023. PMID: 37747887 Free PMC article.
110 results