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Proceedings of the Comprehensive Oncology Network Evaluating Rare CNS Tumors (NCI-CONNECT) Adult Medulloblastoma Workshop.
Penas-Prado M, Theeler BJ, Cordeiro B, Dunkel IJ, Hau P, Mahajan A, Robinson GW, Willmarth N, Aboud O, Aldape K, Butman JA, Gajjar A, Kelly W, Rao G, Raygada M, Siegel C, Romo CG, Armstrong TS, Gilbert MR; NCI-CONNECT Adult Medulloblastoma Workshop. Penas-Prado M, et al. Among authors: aldape k. Neurooncol Adv. 2020 Aug 17;2(1):vdaa097. doi: 10.1093/noajnl/vdaa097. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33005896 Free PMC article. Review.
Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.
Sievers P, Sill M, Blume C, Tauziede-Espariat A, Schrimpf D, Stichel D, Reuss DE, Dogan H, Hartmann C, Mawrin C, Hasselblatt M, Stummer W, Schick U, Hench J, Frank S, Ketter R, Schweizer L, Schittenhelm J, Puget S, Brandner S, Jaunmuktane Z, Küsters B, Abdullaev Z, Pekmezci M, Snuderl M, Ratliff M, Herold-Mende C, Unterberg A, Aldape K, Ellison DW, Wesseling P, Reifenberger G, Wick W, Perry A, Varlet P, Pfister SM, Jones DTW, von Deimling A, Sahm F; German Consortium “Aggressive Meningiomas”. Sievers P, et al. Among authors: aldape k. Acta Neuropathol. 2021 Feb;141(2):281-290. doi: 10.1007/s00401-020-02247-2. Epub 2020 Dec 14. Acta Neuropathol. 2021. PMID: 33319313 Free PMC article.
A novel ATXN1-DUX4 fusion expands the spectrum of 'CIC-rearranged sarcoma' of the CNS to include non-CIC alterations.
Pratt D, Kumar-Sinha C, Cieślik M, Mehra R, Xiao H, Shao L, Franson A, Cantor E, Chinnaiyan AM, Mody R, Abdullaev Z, Aldape K, Quezado M, Camelo-Piragua S. Pratt D, et al. Among authors: aldape k. Acta Neuropathol. 2021 Apr;141(4):619-622. doi: 10.1007/s00401-021-02278-3. Epub 2021 Feb 7. Acta Neuropathol. 2021. PMID: 33550509 No abstract available.
Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.
Suwala AK, Stichel D, Schrimpf D, Maas SLN, Sill M, Dohmen H, Banan R, Reinhardt A, Sievers P, Hinz F, Blattner-Johnson M, Hartmann C, Schweizer L, Boldt HB, Kristensen BW, Schittenhelm J, Wood MD, Chotard G, Bjergvig R, Das A, Tabori U, Hasselblatt M, Korshunov A, Abdullaev Z, Quezado M, Aldape K, Harter PN, Snuderl M, Hench J, Frank S, Acker T, Brandner S, Winkler F, Wesseling P, Pfister SM, Reuss DE, Wick W, von Deimling A, Jones DTW, Sahm F. Suwala AK, et al. Among authors: aldape k. Acta Neuropathol. 2021 Jul;142(1):179-189. doi: 10.1007/s00401-021-02302-6. Epub 2021 Apr 19. Acta Neuropathol. 2021. PMID: 33876327 Free PMC article.
Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.
Sievers P, Henneken SC, Blume C, Sill M, Schrimpf D, Stichel D, Okonechnikov K, Reuss DE, Benzel J, Maaß KK, Kool M, Sturm D, Zheng T, Ghasemi DR, Kohlhof-Meinecke P, Cruz O, Suñol M, Lavarino C, Ruf V, Boldt HB, Pagès M, Pouget C, Schweizer L, Kranendonk MEG, Akhtar N, Bunkowski S, Stadelmann C, Schüller U, Mueller WC, Dohmen H, Acker T, Harter PN, Mawrin C, Beschorner R, Brandner S, Snuderl M, Abdullaev Z, Aldape K, Gilbert MR, Armstrong TS, Ellison DW, Capper D, Ichimura K, Reifenberger G, Grundy RG, Jabado N, Krskova L, Zapotocky M, Vicha A, Varlet P, Wesseling P, Rutkowski S, Korshunov A, Wick W, Pfister SM, Jones DTW, von Deimling A, Pajtler KW, Sahm F. Sievers P, et al. Among authors: aldape k. Acta Neuropathol. 2021 Nov;142(5):827-839. doi: 10.1007/s00401-021-02356-6. Epub 2021 Aug 5. Acta Neuropathol. 2021. PMID: 34355256 Free PMC article.
Report of Canonical BCR-ABL1 Fusion in Glioblastoma.
Pang Y, Yu G, Butler M, Sindiri S, Song YK, Wei JS, Wen X, Chou HC, Quezado M, Pack S, Xi L, Abdullaev Z, Kim O, Ranjan A, Merchant M, Antony R, Boris L, Aboud O, Kamson D, Kaplan R, Mackey M, Camphausen K, Zaghloul K, Armstrong TS, Gilbert MR, Aldape K, Holdhoff M, Khan J, Wu J. Pang Y, et al. Among authors: aldape k. JCO Precis Oncol. 2021 Aug 25;5:PO.20.00519. doi: 10.1200/PO.20.00519. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34485806 Free PMC article. No abstract available.
Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics.
Wu Z, Abdullaev Z, Pratt D, Chung HJ, Skarshaug S, Zgonc V, Perry C, Pack S, Saidkhodjaeva L, Nagaraj S, Tyagi M, Gangalapudi V, Valdez K, Turakulov R, Xi L, Raffeld M, Papanicolau-Sengos A, O'Donnell K, Newford M, Gilbert MR, Sahm F, Suwala AK, von Deimling A, Mamatjan Y, Karimi S, Nassiri F, Zadeh G, Ruppin E, Quezado M, Aldape K. Wu Z, et al. Among authors: aldape k. Neuro Oncol. 2022 Apr 1;24(4):571-581. doi: 10.1093/neuonc/noab227. Neuro Oncol. 2022. PMID: 34555175 Free PMC article.
High-grade glioma with pleomorphic and pseudopapillary features (HPAP): a proposed type of circumscribed glioma in adults harboring frequent TP53 mutations and recurrent monosomy 13.
Pratt D, Abdullaev Z, Papanicolau-Sengos A, Ketchum C, Panneer Selvam P, Chung HJ, Lee I, Raffeld M, Gilbert MR, Armstrong TS, Pytel P, Borys E, Klonoski JM, McCord M, Horbinski C, Brat D, Perry A, Solomon D, Eberhart C, Giannini C, Quezado M, Aldape K. Pratt D, et al. Among authors: aldape k. Acta Neuropathol. 2022 Mar;143(3):403-414. doi: 10.1007/s00401-022-02404-9. Epub 2022 Feb 1. Acta Neuropathol. 2022. PMID: 35103816 Free PMC article.
639 results