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Page 1
GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model.
Ortiz DA, Peregrín N, Valencia M, Vinueza-Gavilanes R, Marín-Ordovas E, Ferrero R, Nicolás MJ, González-Aseguinolaza G, Arrasate M, Aragón T. Ortiz DA, et al. Among authors: gonzalez aseguinolaza g. Transl Neurodegener. 2024 Sep 20;13(1):49. doi: 10.1186/s40035-024-00441-w. Transl Neurodegener. 2024. PMID: 39304897 Free PMC article. No abstract available.
Enhanced AAV transduction across preclinical CNS models: A comparative study in human brain organoids with cross-species evaluations.
Drouyer M, Merjane J, Nedelkoska T, Westhaus A, Scott S, Lee S, Burke PGR, McMullan S, Lanciego JL, Vicente AF, Bugallo R, Unzu C, González-Aseguinolaza G, Gonzalez-Cordero A, Lisowski L. Drouyer M, et al. Among authors: gonzalez aseguinolaza g. Mol Ther Nucleic Acids. 2024 Jun 28;35(3):102264. doi: 10.1016/j.omtn.2024.102264. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39108635 Free PMC article.
Profile of plasma microRNAs as a potential biomarker of Wilson's disease.
Sánchez-Monteagudo A, Ripollés E, Murillo O, Domènech S, Álvarez-Sauco M, Girona E, Sastre-Bataller I, Bono A, García-Villarreal L, Tugores A, García-García F, González-Aseguinolaza G, Berenguer M, Espinós C. Sánchez-Monteagudo A, et al. Among authors: gonzalez aseguinolaza g. J Gastroenterol. 2024 Oct;59(10):921-931. doi: 10.1007/s00535-024-02135-6. Epub 2024 Jul 26. J Gastroenterol. 2024. PMID: 39060521 Free PMC article.
In Vivo Selection of S/MAR Sequences to Favour AAV Episomal Maintenance in Dividing Cells.
Llanos-Ardaiz A, Lantero A, Neri L, Mauleón I, Ruiz de Galarreta M, Trigueros-Motos L, Weber ND, Ferrer V, Aldabe R, Gonzalez-Aseguinolaza G. Llanos-Ardaiz A, et al. Among authors: gonzalez aseguinolaza g. Int J Mol Sci. 2024 Nov 27;25(23):12734. doi: 10.3390/ijms252312734. Int J Mol Sci. 2024. PMID: 39684442 Free PMC article.
Gene editing in liver diseases.
Torella L, Santana-Gonzalez N, Zabaleta N, Gonzalez Aseguinolaza G. Torella L, et al. Among authors: gonzalez aseguinolaza g. FEBS Lett. 2024 Oct;598(19):2348-2371. doi: 10.1002/1873-3468.14989. Epub 2024 Jul 30. FEBS Lett. 2024. PMID: 39079936 Review.
Protective role of RIPK1 scaffolding against HDV-induced hepatocyte cell death and the significance of cytokines in mice.
Camps G, Maestro S, Torella L, Herrero D, Usai C, Bilbao-Arribas M, Aldaz A, Olagüe C, Vales A, Suárez-Amarán L, Aldabe R, Gonzalez-Aseguinolaza G. Camps G, et al. Among authors: gonzalez aseguinolaza g. PLoS Pathog. 2024 May 13;20(5):e1011749. doi: 10.1371/journal.ppat.1011749. eCollection 2024 May. PLoS Pathog. 2024. PMID: 38739648 Free PMC article.
Harnessing whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation.
Cabanes-Creus M, Liao SHY, Gale Navarro R, Knight M, Nazareth D, Lau NS, Ly M, Zhu E, Roca-Pinilla R, Bugallo Delgado R, Vicente AF, Baltazar G, Westhaus A, Merjane J, Crawford M, McCaughan GW, Unzu C, González-Aseguinolaza G, Alexander IE, Pulitano C, Lisowski L. Cabanes-Creus M, et al. Among authors: gonzalez aseguinolaza g. Nat Commun. 2024 Mar 14;15(1):1876. doi: 10.1038/s41467-024-46194-y. Nat Commun. 2024. PMID: 38485924 Free PMC article.
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1.
Torella L, Klermund J, Bilbao-Arribas M, Tamayo I, Andrieux G, Chmielewski KO, Vales A, Olagüe C, Moreno-Luqui D, Raimondi I, Abad A, Torrens-Baile J, Salido E, Huarte M, Hernaez M, Boerries M, Cathomen T, Zabaleta N, Gonzalez-Aseguinolaza G. Torella L, et al. Among authors: gonzalez aseguinolaza g. EMBO Mol Med. 2024 Jan;16(1):112-131. doi: 10.1038/s44321-023-00008-8. Epub 2024 Jan 5. EMBO Mol Med. 2024. PMID: 38182795 Free PMC article.
155 results