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Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction.
Wood GK, Sargent BF, Ahmad ZU, Tharmaratnam K, Dunai C, Egbe FN, Martin NH, Facer B, Pendered SL, Rogers HC, Hübel C, van Wamelen DJ, Bethlehem RAI, Giunchiglia V, Hellyer PJ, Trender W, Kalsi G, Needham E, Easton A, Jackson TA, Cunningham C, Upthegrove R, Pollak TA, Hotopf M, Solomon T, Pett SL, Shaw PJ, Wood N, Harrison NA, Miller KL, Jezzard P, Williams G, Duff EP, Williams S, Zelaya F, Smith SM, Keller S, Broome M, Kingston N, Husain M, Vincent A, Bradley J, Chinnery P, Menon DK, Aggleton JP, Nicholson TR, Taylor JP, David AS, Carson A, Bullmore E, Breen G, Hampshire A; COVID-CNS Consortium; Michael BD, Paddick SM, Leek EC. Wood GK, et al. Among authors: needham e. Nat Med. 2024 Sep 23. doi: 10.1038/s41591-024-03309-8. Online ahead of print. Nat Med. 2024. PMID: 39312956
The immunological response to traumatic brain injury.
Needham EJ, Helmy A, Zanier ER, Jones JL, Coles AJ, Menon DK. Needham EJ, et al. J Neuroimmunol. 2019 Jul 15;332:112-125. doi: 10.1016/j.jneuroim.2019.04.005. Epub 2019 Apr 11. J Neuroimmunol. 2019. PMID: 31005712 Review.
Neurological Implications of COVID-19 Infections.
Needham EJ, Chou SH, Coles AJ, Menon DK. Needham EJ, et al. Neurocrit Care. 2020 Jun;32(3):667-671. doi: 10.1007/s12028-020-00978-4. Neurocrit Care. 2020. PMID: 32346843 Free PMC article.
Neuroanatomical substrates of generalized brain dysfunction in COVID-19.
Newcombe VFJ, Spindler LRB, Das T, Winzeck S, Allinson K, Stamatakis EA, Menon DK; Cambridge NeuroCovid Imaging Collaborators. Newcombe VFJ, et al. Intensive Care Med. 2021 Jan;47(1):116-118. doi: 10.1007/s00134-020-06241-w. Epub 2020 Oct 9. Intensive Care Med. 2021. PMID: 33034688 Free PMC article. No abstract available.
Post-acute blood biomarkers and disease progression in traumatic brain injury.
Newcombe VFJ, Ashton NJ, Posti JP, Glocker B, Manktelow A, Chatfield DA, Winzeck S, Needham E, Correia MM, Williams GB, Simrén J, Takala RSK, Katila AJ, Maanpää HR, Tallus J, Frantzén J, Blennow K, Tenovuo O, Zetterberg H, Menon DK. Newcombe VFJ, et al. Among authors: needham e. Brain. 2022 Jun 30;145(6):2064-2076. doi: 10.1093/brain/awac126. Brain. 2022. PMID: 35377407 Free PMC article.
Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.
Needham EJ, Ren AL, Digby RJ, Norton EJ, Ebrahimi S, Outtrim JG, Chatfield DA, Manktelow AE, Leibowitz MM, Newcombe VFJ, Doffinger R, Barcenas-Morales G, Fonseca C, Taussig MJ, Burnstein RM, Samanta RJ, Dunai C, Sithole N, Ashton NJ, Zetterberg H, Gisslén M, Edén A, Marklund E, Openshaw PJM, Dunning J, Griffiths MJ, Cavanagh J, Breen G, Irani SR, Elmer A, Kingston N, Summers C, Bradley JR, Taams LS, Michael BD, Bullmore ET, Smith KGC, Lyons PA, Coles AJ, Menon DK; Cambridge NeuroCOVID Group; CITIID-NIHR COVID-19 BioResource Collaboration; Cambridge NIHR Clinical Research Facility. Needham EJ, et al. Brain. 2022 Nov 21;145(11):4097-4107. doi: 10.1093/brain/awac321. Brain. 2022. PMID: 36065116 Free PMC article.
86 results