Schmitt-Ulms G - Search Results

1

Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigms.

Eid S, Zhao W, Williams D, Nasser Z, Griffin J, Nagorny P, Schmitt-Ulms G. Eid S, et al. Among authors: schmitt ulms g. PLoS One. 2024 Sep 24;19(9):e0308821. doi: 10.1371/journal.pone.0308821. eCollection 2024. PLoS One. 2024. PMID: 39316592 Free PMC article.

2

The cellular prion protein interacts with and promotes the activity of Na,K-ATPases.

Williams D, Mehrabian M, Arshad H, Eid S, Sackmann C, Zhao W, Wang X, Ghodrati F, Verkuyl CE, Watts JC, Schmitt-Ulms G. Williams D, et al. Among authors: schmitt ulms g. PLoS One. 2021 Nov 30;16(11):e0258682. doi: 10.1371/journal.pone.0258682. eCollection 2021. PLoS One. 2021. PMID: 34847154 Free PMC article.

3

Cardiac glycoside-mediated turnover of Na, K-ATPases as a rational approach to reducing cell surface levels of the cellular prion protein.

Mehrabian M, Wang X, Eid S, Yan BQ, Grinberg M, Siegner M, Sackmann C, Sulman M, Zhao W, Williams D, Schmitt-Ulms G. Mehrabian M, et al. Among authors: schmitt ulms g. PLoS One. 2022 Jul 1;17(7):e0270915. doi: 10.1371/journal.pone.0270915. eCollection 2022. PLoS One. 2022. PMID: 35776750 Free PMC article.

4

Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein.

Eid S, Zerbes T, Williams D, Wang X, Sackmann C, Meier S, Dulin NO, Nagorny P, Schmitt-Ulms G. Eid S, et al. Among authors: schmitt ulms g. Int J Mol Sci. 2022 Nov 26;23(23):14823. doi: 10.3390/ijms232314823. Int J Mol Sci. 2022. PMID: 36499150 Free PMC article.

5

Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue.

Mehrabian M, Brethour D, Williams D, Wang H, Arnould H, Schneider B, Schmitt-Ulms G. Mehrabian M, et al. PLoS One. 2016 Jun 21;11(6):e0156779. doi: 10.1371/journal.pone.0156779. eCollection 2016. PLoS One. 2016. PMID: 27327609 Free PMC article.

6

Time-course global proteome analyses reveal an inverse correlation between Aβ burden and immunoglobulin M levels in the APPNL-F mouse model of Alzheimer disease.

Wang H, Williams D, Griffin J, Saito T, Saido TC, Fraser PE, Rogaeva E, Schmitt-Ulms G. Wang H, et al. PLoS One. 2017 Aug 23;12(8):e0182844. doi: 10.1371/journal.pone.0182844. eCollection 2017. PLoS One. 2017. PMID: 28832675 Free PMC article.

7

The human brain somatostatin interactome: SST binds selectively to P-type family ATPases.

Solarski M, Williams D, Mehrabian M, Wang H, Wille H, Schmitt-Ulms G. Solarski M, et al. PLoS One. 2019 May 28;14(5):e0217392. doi: 10.1371/journal.pone.0217392. eCollection 2019. PLoS One. 2019. PMID: 31136617 Free PMC article.

8

The IDIP framework for assessing protein function and its application to the prion protein.

Schmitt-Ulms G, Mehrabian M, Williams D, Ehsani S. Schmitt-Ulms G, et al. Biol Rev Camb Philos Soc. 2021 Oct;96(5):1907-1932. doi: 10.1111/brv.12731. Epub 2021 May 6. Biol Rev Camb Philos Soc. 2021. PMID: 33960099 Review.

9

The molecular determinants of a universal prion acceptor.

Arshad H, Patel Z, Al-Azzawi ZAM, Amano G, Li L, Mehra S, Eid S, Schmitt-Ulms G, Watts JC. Arshad H, et al. Among authors: schmitt ulms g. PLoS Pathog. 2024 Sep 10;20(9):e1012538. doi: 10.1371/journal.ppat.1012538. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39255320 Free PMC article.

10

The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling.

Ghodrati F, Mehrabian M, Williams D, Halgas O, Bourkas MEC, Watts JC, Pai EF, Schmitt-Ulms G. Ghodrati F, et al. Sci Rep. 2018 Jun 5;8(1):8654. doi: 10.1038/s41598-018-26685-x. Sci Rep. 2018. PMID: 29872131 Free PMC article.

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