Ostenfeld T - Search Results

1

MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non-clinical species and Alzheimer's disease patients.

Lloyd C, Freskgård PO, Newton P, Lowne D, Nickson A, Bogstedt A, Eketjäll S, Höglund K, Gustavsson S, Welsh F, Chessell T, McFarlane M, Bhat RV, Turner R, Perkinton MS, Santisteban Valencia Z, Lindqvist E, Pomfret M, Dudley AD, Vaughan TJ, Groves MT, Natanegara F, Feng Y, Sims JR, Proctor NK, Dage JL, Shering C, Tan K, Ostenfeld T, Billinton A, Chessell IP. Lloyd C, et al. Among authors: ostenfeld t. Alzheimers Dement. 2024 Nov;20(11):7762-7776. doi: 10.1002/alz.14238. Epub 2024 Sep 25. Alzheimers Dement. 2024. PMID: 39319998 Free PMC article.

2

A randomized, placebo-controlled trial of the analgesic efficacy and safety of the p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain from lumbosacral radiculopathy.

Ostenfeld T, Krishen A, Lai RY, Bullman J, Green J, Anand P, Scholz J, Kelly M. Ostenfeld T, et al. Clin J Pain. 2015 Apr;31(4):283-93. doi: 10.1097/AJP.0000000000000122. Clin J Pain. 2015. PMID: 25751578 Clinical Trial.

3

Analgesic efficacy and safety of the novel p38 MAP kinase inhibitor, losmapimod, in patients with neuropathic pain following peripheral nerve injury: a double-blind, placebo-controlled study.

Ostenfeld T, Krishen A, Lai RY, Bullman J, Baines AJ, Green J, Anand P, Kelly M. Ostenfeld T, et al. Eur J Pain. 2013 Jul;17(6):844-57. doi: 10.1002/j.1532-2149.2012.00256.x. Epub 2012 Dec 14. Eur J Pain. 2013. PMID: 23239139 Clinical Trial.

4

Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects.

Ali Z, Laurijssens B, Ostenfeld T, McHugh S, Stylianou A, Scott-Stevens P, Hosking L, Dewit O, Richardson JC, Chen C. Ali Z, et al. Among authors: ostenfeld t. Br J Clin Pharmacol. 2013 Jan;75(1):197-207. doi: 10.1111/j.1365-2125.2012.04320.x. Br J Clin Pharmacol. 2013. PMID: 22568863 Free PMC article. Clinical Trial.

5

Human microdose evaluation of the novel EP1 receptor antagonist GSK269984A.

Ostenfeld T, Beaumont C, Bullman J, Beaumont M, Jeffrey P. Ostenfeld T, et al. Br J Clin Pharmacol. 2012 Dec;74(6):1033-44. doi: 10.1111/j.1365-2125.2012.04296.x. Br J Clin Pharmacol. 2012. PMID: 22497298 Free PMC article.

6

Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury.

Anand P, Shenoy R, Palmer JE, Baines AJ, Lai RY, Robertson J, Bird N, Ostenfeld T, Chizh BA. Anand P, et al. Among authors: ostenfeld t. Eur J Pain. 2011 Nov;15(10):1040-8. doi: 10.1016/j.ejpain.2011.04.005. Epub 2011 May 14. Eur J Pain. 2011. PMID: 21576029 Clinical Trial.

7

A randomized, controlled study to investigate the analgesic efficacy of single doses of the cannabinoid receptor-2 agonist GW842166, ibuprofen or placebo in patients with acute pain following third molar tooth extraction.

Ostenfeld T, Price J, Albanese M, Bullman J, Guillard F, Meyer I, Leeson R, Costantin C, Ziviani L, Nocini PF, Milleri S. Ostenfeld T, et al. Clin J Pain. 2011 Oct;27(8):668-76. doi: 10.1097/AJP.0b013e318219799a. Clin J Pain. 2011. PMID: 21540741 Clinical Trial.

8

Requirement for neurogenesis to proceed through the division of neuronal progenitors following differentiation of epidermal growth factor and fibroblast growth factor-2-responsive human neural stem cells.

Ostenfeld T, Svendsen CN. Ostenfeld T, et al. Stem Cells. 2004;22(5):798-811. doi: 10.1634/stemcells.22-5-798. Stem Cells. 2004. PMID: 15342944

9

Recent advances in stem cell neurobiology.

Ostenfeld T, Svendsen CN. Ostenfeld T, et al. Adv Tech Stand Neurosurg. 2003;28:3-89. doi: 10.1007/978-3-7091-0641-9_1. Adv Tech Stand Neurosurg. 2003. PMID: 12627808 Review.

10

Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons.

Ostenfeld T, Tai YT, Martin P, Déglon N, Aebischer P, Svendsen CN. Ostenfeld T, et al. J Neurosci Res. 2002 Sep 15;69(6):955-65. doi: 10.1002/jnr.10396. J Neurosci Res. 2002. PMID: 12205689

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