Zhu J - Search Results

1

Inhibition of heme-thiolate monooxygenase CYP1B1 prevents hepatic stellate cell activation and liver fibrosis by accumulating trehalose.

Tung HC, Kim JW, Zhu J, Li S, Yan J, Liu Q, Koo I, Koshkin SA, Hao F, Zhong G, Xu M, Wang Z, Wang J, Huang Y, Xi Y, Cai X, Xu P, Ren S, Higashiyama T, Gonzalez FJ, Li S, Isoherranen N, Yang D, Ma X, Patterson AD, Xie W. Tung HC, et al. Among authors: zhu j. Sci Transl Med. 2024 Sep 25;16(766):eadk8446. doi: 10.1126/scitranslmed.adk8446. Epub 2024 Sep 25. Sci Transl Med. 2024. PMID: 39321267

2

Metabolism of KO143, an ABCG2 inhibitor.

Liu K, Zhu J, Huang Y, Li C, Lu J, Sachar M, Li S, Ma X. Liu K, et al. Among authors: zhu j. Drug Metab Pharmacokinet. 2017 Aug;32(4):193-200. doi: 10.1016/j.dmpk.2017.02.003. Epub 2017 Mar 6. Drug Metab Pharmacokinet. 2017. PMID: 28619281

3

Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis.

Bi Y, Shi X, Zhu J, Guan X, Garbacz WG, Huang Y, Gao L, Yan J, Xu M, Ren S, Ren S, Liu Y, Ma X, Li S, Xie W. Bi Y, et al. Among authors: zhu j. Mol Cell Biol. 2018 Mar 15;38(7):e00654-17. doi: 10.1128/MCB.00654-17. Print 2018 Apr 1. Mol Cell Biol. 2018. PMID: 29378829 Free PMC article.

4

Identification of Novel Pathways in Idelalisib Metabolism and Bioactivation.

Zhu J, Wang P, Shehu AI, Lu J, Bi H, Ma X. Zhu J, et al. Chem Res Toxicol. 2018 Jul 16;31(7):548-555. doi: 10.1021/acs.chemrestox.8b00023. Epub 2018 Jun 26. Chem Res Toxicol. 2018. PMID: 29896955 Free PMC article.

5

CYP1A1 and 1B1-mediated metabolic pathways of dolutegravir, an HIV integrase inhibitor.

Zhu J, Wang P, Li F, Lu J, Shehu AI, Xie W, McMahon D, Ma X. Zhu J, et al. Biochem Pharmacol. 2018 Dec;158:174-184. doi: 10.1016/j.bcp.2018.10.012. Epub 2018 Oct 17. Biochem Pharmacol. 2018. PMID: 30342022 Free PMC article.

6

Time-dependent inhibition of carbamazepine metabolism by piperine in anti-epileptic treatment.

Ren T, Yang M, Xiao M, Zhu J, Xie W, Zuo Z. Ren T, et al. Among authors: zhu j. Life Sci. 2019 Feb 1;218:314-323. doi: 10.1016/j.lfs.2018.12.060. Epub 2019 Jan 3. Life Sci. 2019. PMID: 30611786

7

Dual functional immunostimulatory polymeric prodrug carrier with pendent indoximod for enhanced cancer immunochemotherapy.

Wan Z, Sun J, Xu J, Moharil P, Chen J, Xu J, Zhu J, Li J, Huang Y, Xu P, Ma X, Xie W, Lu B, Li S. Wan Z, et al. Among authors: zhu j. Acta Biomater. 2019 May;90:300-313. doi: 10.1016/j.actbio.2019.03.048. Epub 2019 Mar 28. Acta Biomater. 2019. PMID: 30930305 Free PMC article.

8

Pregnane X receptor activation potentiates ritonavir hepatotoxicity.

Shehu AI, Lu J, Wang P, Zhu J, Wang Y, Yang D, McMahon D, Xie W, Gonzalez FJ, Ma X. Shehu AI, et al. Among authors: zhu j. J Clin Invest. 2019 Apr 30;129(7):2898-2903. doi: 10.1172/JCI128274. J Clin Invest. 2019. PMID: 31039134 Free PMC article.

9

Enzymes and Pathways of Kavain Bioactivation and Biotransformation.

Wang P, Zhu J, Shehu AI, Lu J, Chen J, Zhong XB, Ma X. Wang P, et al. Among authors: zhu j. Chem Res Toxicol. 2019 Jul 15;32(7):1335-1342. doi: 10.1021/acs.chemrestox.9b00098. Epub 2019 Jul 2. Chem Res Toxicol. 2019. PMID: 31265262

10

The essential role of the transporter ABCG2 in the pathophysiology of erythropoietic protoporphyria.

Wang P, Sachar M, Lu J, Shehu AI, Zhu J, Chen J, Liu K, Anderson KE, Xie W, Gonzalez FJ, Klaassen CD, Ma X. Wang P, et al. Among authors: zhu j. Sci Adv. 2019 Sep 18;5(9):eaaw6127. doi: 10.1126/sciadv.aaw6127. eCollection 2019 Sep. Sci Adv. 2019. PMID: 31555729 Free PMC article.

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