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Page 1
DNA methylation as a new tool for the differential diagnosis between T-LBL and lymphocyte-rich thymoma.
Latiri M, Belhocine M, Smith C, Garnier N, Balducci E, Pinton A, Andrieu GP, Bruneau J, Spicuglia S, Jamain S, Latapie V, de Montpreville VT, Chalabreysse L, Marx A, Girard N, Besse B, Plass C, Gibault L, Badoual C, Macintyre E, Asnafi V, Molina TJ, Touzart A. Latiri M, et al. Among authors: belhocine m. J Pathol. 2024 Nov;264(3):284-292. doi: 10.1002/path.6346. Epub 2024 Sep 27. J Pathol. 2024. PMID: 39329449
Low level CpG island promoter methylation predicts a poor outcome in adult T-cell acute lymphoblastic leukemia.
Touzart A, Boissel N, Belhocine M, Smith C, Graux C, Latiri M, Lhermitte L, Mathieu EL, Huguet F, Lamant L, Ferrier P, Ifrah N, Macintyre E, Dombret H, Asnafi V, Spicuglia S. Touzart A, et al. Among authors: belhocine m. Haematologica. 2020 Jun;105(6):1575-1581. doi: 10.3324/haematol.2019.223677. Epub 2019 Sep 19. Haematologica. 2020. PMID: 31537687 Free PMC article.
Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL.
Touzart A, Lengliné E, Latiri M, Belhocine M, Smith C, Thomas X, Spicuglia S, Puthier D, Pflumio F, Leguay T, Graux C, Chalandon Y, Huguet F, Leprêtre S, Ifrah N, Dombret H, Macintyre E, Hunault M, Boissel N, Asnafi V. Touzart A, et al. Among authors: belhocine m. Clin Cancer Res. 2019 Apr 15;25(8):2483-2493. doi: 10.1158/1078-0432.CCR-18-1844. Epub 2019 Jan 18. Clin Cancer Res. 2019. PMID: 30659025
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation.
Cieslak A, Charbonnier G, Tesio M, Mathieu EL, Belhocine M, Touzart A, Smith C, Hypolite G, Andrieu GP, Martens JHA, Janssen-Megens E, Gut M, Gut I, Boissel N, Petit A, Puthier D, Macintyre E, Stunnenberg HG, Spicuglia S, Asnafi V. Cieslak A, et al. Among authors: belhocine m. J Exp Med. 2020 Sep 7;217(9):e20192360. doi: 10.1084/jem.20192360. J Exp Med. 2020. PMID: 32667968 Free PMC article.
Dynamics of broad H3K4me3 domains uncover an epigenetic switch between cell identity and cancer-related genes.
Belhocine M, Simonin M, Abad Flores JD, Cieslak A, Manosalva I, Pradel L, Smith C, Mathieu EL, Charbonnier G, Martens JHA, Stunnenberg HG, Maqbool MA, Mikulasova A, Russell LJ, Rico D, Puthier D, Ferrier P, Asnafi V, Spicuglia S. Belhocine M, et al. Genome Res. 2022 Jul;32(7):1328-1342. doi: 10.1101/gr.266924.120. Epub 2021 Jun 23. Genome Res. 2022. PMID: 34162697 Free PMC article.
Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.
Trinquand A, Dos Santos NR, Tran Quang C, Rocchetti F, Zaniboni B, Belhocine M, Da Costa de Jesus C, Lhermitte L, Tesio M, Dussiot M, Cosset FL, Verhoeyen E, Pflumio F, Ifrah N, Dombret H, Spicuglia S, Chatenoud L, Gross DA, Hermine O, Macintyre E, Ghysdael J, Asnafi V. Trinquand A, et al. Among authors: belhocine m. Cancer Discov. 2016 Sep;6(9):972-85. doi: 10.1158/2159-8290.CD-15-0675. Epub 2016 Jun 28. Cancer Discov. 2016. PMID: 27354269
TCRα rearrangements identify a subgroup of NKL-deregulated adult T-ALLs associated with favorable outcome.
Villarese P, Lours C, Trinquand A, Le Noir S, Belhocine M, Lhermitte L, Cieslak A, Tesio M, Petit A, LeLorch M, Spicuglia S, Ifrah N, Dombret H, Langerak AW, Boissel N, Macintyre E, Asnafi V. Villarese P, et al. Among authors: belhocine m. Leukemia. 2018 Jan;32(1):61-71. doi: 10.1038/leu.2017.176. Epub 2017 Jun 8. Leukemia. 2018. PMID: 28592888 Clinical Trial.
A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis.
Bond J, Krzywon A, Lhermitte L, Roumier C, Roggy A, Belhocine M, Kheirallah AA, Villarese P, Hypolite G, Garnache-Ottou F, Castaigne S, Boissel N, Asnafi V, Preudhomme C, Dombret H, Laurenti E, Macintyre E. Bond J, et al. Among authors: belhocine m. Leukemia. 2021 Mar;35(3):724-736. doi: 10.1038/s41375-020-0965-z. Epub 2020 Jul 13. Leukemia. 2021. PMID: 32655144 Free PMC article.
35 results