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Page 1
Effect of Opaganib on Supplemental Oxygen and Mortality in Patients with Severe SARS-CoV-2 Based upon FIO2 Requirements.
Neuenschwander FC, Barnett-Griness O, Piconi S, Maor Y, Sprinz E, Assy N, Khmelnitskiy O, Lomakin NV, Goloshchekin BM, Nahorecka E, Joaquim Westheimer Calvacante A, Ivanova A, Vladimirovich Zhuravel S, Yurevna Trufanova G, Bonora S, Saffoury A, Mayo A, Shvarts YG, Rizzardini G, Sobroza de Mello R, Pilau J, Klinov A, Valente-Acosta B, Olegovich Burlaka O, Bakhtina N, Bar-Meir M, Nikolaevich Shishimorov I, Oñate-Gutierrez J, García Rincón CI, Ivanovna Martynenko T, Hajjar LA, Carolina Nazare de Mendonca Procopio A, Simon K, Gabriel Chaves Santiago W, Fronczak A, Roberto Hoffmann Filho C, Hussein O, Aleksandrovich Martynov V, Chichino G, Blewaska P, Wroblewski J, Saul Irizar Santana S, Felipe Ocampo Agudelo A, Barczyk A, Lask Gerlach R, Campbell E, Bibliowicz A, Fathi R, Anderson P, Raday G, Klein M, Fehrmann C, Eagle G, Ben-Yair VK, Levitt ML. Neuenschwander FC, et al. Among authors: ben yair vk. Microorganisms. 2024 Aug 26;12(9):1767. doi: 10.3390/microorganisms12091767. Microorganisms. 2024. PMID: 39338442 Free PMC article.
Combined Antitumor Effect of the Serine Protease Urokinase Inhibitor Upamostat and the Sphingosine Kinase 2 Inhibitor Opaganib on Cholangiocarcinoma Patient-Derived Xenografts.
Asumda FZ, Campbell NA, Hassan MA, Fathi R, Vasquez Rico DF, Kiem M, Vang EV, Kim YH, Luo X, O'Brien DR, Buhrow SA, Reid JM, Moore MJ, Ben-Yair VK, Levitt ML, Leiting JL, Abdelrahman AM, Zhu X, Lucien F, Truty MJ, Roberts LR. Asumda FZ, et al. Among authors: ben yair vk. Cancers (Basel). 2024 Mar 5;16(5):1050. doi: 10.3390/cancers16051050. Cancers (Basel). 2024. PMID: 38473407 Free PMC article.
Phase I study of opaganib, an oral sphingosine kinase 2-specific inhibitor, in relapsed and/or refractory multiple myeloma.
Kang Y, Sundaramoorthy P, Gasparetto C, Feinberg D, Fan S, Long G, Sellars E, Garrett A, Tuchman SA, Reeves BN, Li Z, Liu B, Ogretmen B, Maines L, Ben-Yair VK, Smith C, Plasse T. Kang Y, et al. Among authors: ben yair vk. Ann Hematol. 2023 Feb;102(2):369-383. doi: 10.1007/s00277-022-05056-7. Epub 2022 Dec 3. Ann Hematol. 2023. PMID: 36460794 Clinical Trial.
Opaganib in Coronavirus Disease 2019 Pneumonia: Results of a Randomized, Placebo-Controlled Phase 2a Trial.
Winthrop KL, Skolnick AW, Rafiq AM, Beegle SH, Suszanski J, Koehne G, Barnett-Griness O, Bibliowicz A, Fathi R, Anderson P, Raday G, Eagle G, Ben-Yair VK, Minkowitz HS, Levitt ML, Gordon MS. Winthrop KL, et al. Among authors: ben yair vk. Open Forum Infect Dis. 2022 May 11;9(7):ofac232. doi: 10.1093/ofid/ofac232. eCollection 2022 Jul. Open Forum Infect Dis. 2022. PMID: 35832268 Free PMC article.